Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 13 de 13
Filtrar
1.
J Dent ; 146: 105000, 2024 07.
Artículo en Inglés | MEDLINE | ID: mdl-38734300

RESUMEN

OBJECTIVE: This systematic review evaluated the occlusal changes after loading with implant-supported single crowns. SOURCES: An electronic literature search was conducted in PubMed, Embase and Cochrane library for randomized (RCTs) or non-randomized controlled clinical trials (CCTs), with a minimum of 10 patients. STUDY SELECTION: Studies reporting the occlusal force changes on implant-supported single crowns - with natural teeth as antagonist - measured at baseline and after loading periods were included. 4 CCTs including 133 ISCs in posterior sites were included for meta-analysis. All analyzed ISCs had no contact at a light bite and a light contact at a heavy bite in MIP at loading (baseline). DATA: The relative occlusal forces (ROFs) of each implant-supported single crown (ISC) or control tooth (CT) were extracted. ROFs were defined as percentage of the total occlusal force of the entire dentition at maximum intercuspal position (MIP). A meta-analysis was conducted to compare the ROF changes at different follow-up periods and the weighted mean differences in ROF between ISCs and CTs were pooled and analyzed. The amount of change in ROF was significantly lower in 6 to 12 months after loading comparing the follow-up period between baseline and 6 month (p < 0.05). At baseline and 3-month follow-up, CTs presented significant higher ROF than ISCs (p < 0.05), while no significant difference was found after half year following. CONCLUSIONS: This study showed that the ROF changes significantly over time after loading of ISCs. It might prove that the occlusal concept defined at the time of prosthetic delivery changes or adapts naturally over time. CLINICAL SIGNIFICANCE: The function of specific implant occlusal concept (no contact at a light bite and a light contact at a heavy bite in MIP) is limited over time and careful monitoring and occlusal adjustments should be recommendable during the first-year follow-up.


Asunto(s)
Fuerza de la Mordida , Coronas , Prótesis Dental de Soporte Implantado , Humanos , Implantes Dentales de Diente Único , Estudios de Seguimiento , Oclusión Dental
2.
Int J Implant Dent ; 10(1): 6, 2024 Feb 07.
Artículo en Inglés | MEDLINE | ID: mdl-38324168

RESUMEN

PURPOSE: This study aimed to assess the accuracy of implant placement through three-dimensional planning and fully guided insertion, comparing outcomes between undergraduate and postgraduate surgeons. METHODS: Thirty-eight patients requiring 42 implants in posterior single-tooth gaps were enrolled from the University Clinic for Prosthodontics at the Martin Luther University Halle Wittenberg and the Department of Prosthodontics, Geriatric Dentistry, and Craniomandibular Disorders of Charité University Medicine, Berlin. Twenty-two implants were placed by undergraduate students (n = 18), while 20 implants were placed by trainee postgraduate dentists (n = 5). Pre-operative intraoral scans and cone beam computed tomography images were performed for implant planning and surgical template fabrication. Postoperative intraoral scans were superimposed onto the original scans to analyze implant accuracy in terms of apical, coronal, and angular deviations, as well as vertical discrepancies. RESULTS: In the student group, two implant insertions were performed by the assistant dentist because of intraoperative complications and, thus, were excluded from further analysis. For the remaining implants, no statistically significant differences were observed between the dentist and student groups in terms of apical (p = 0.245), coronal (p = 0.745), or angular (p = 0.185) implant deviations, as well as vertical discrepancies (p = 0.433). CONCLUSIONS: This study confirms the viability of fully guided implant placement by undergraduate students, with comparable accuracy to postgraduate dentists. Integration into dental education can prepare students for implant procedures, expanding access and potentially reducing costs in clinical practice. Collaboration is essential for safe implementation, and future research should explore long-term outcomes and patient perspectives, contributing to the advancement of dental education and practice. TRIAL REGISTRATION: DRKS, DRKS00023024, Registered 8 September 2020-Retrospectively registered, https://drks.de/search/de/trial/DRKS00023024 .


Asunto(s)
Implantes Dentales , Humanos , Odontólogos , Complicaciones Intraoperatorias , Estudios Prospectivos , Estudiantes
3.
Clin Oral Investig ; 27(10): 5875-5886, 2023 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-37581766

RESUMEN

OBJECTIVES: To assess clinical, radiological and esthetic outcomes of restorations supported by root-analogue implants (RAIs) or roots of severely damaged teeth after forced orthodontic extrusion (FOE). MATERIALS AND METHODS: Clinical data regarding milled one-piece (titanium/zirconia roots and zirconia abutments) RAIs (REPLICATE™ System) and FOE were recorded and retrospectively evaluated for 40 patients by two investigators. Strict inclusion and exclusion criteria were applied. Functional and esthetic outcomes were assessed for n = 20 pre-molars and n = 20 anterior teeth via comparison of radiographic and digital images applying the novel Functional Implant Prosthodontic Score (FIPS). Krippendorff's alpha coefficient was calculated to assess inter-rater reliability. Mann-Whitney-U-Test was used to compare the assessed parameters. Level of significance was set to p < 0.05. RESULTS: After a mean observation period of 18.4 ± 5.7 months for restorations supported by RAIs and 43.9 ± 16.4 months for restorations after FOE, mean FIPS scores were 9.2/8.8 ± 1.1/1.2 (RAIs) and 7.4/7.7 ± 1.3/1.5 (FOE), respectively. Krippendorff's alpha coefficients did not reveal unacceptable inter-rater reliabilities regarding the investigators and applicability of FIPS. Significant differences were documented when comparing restorations after FOE or supported by RAIs regarding bone loss (p < 0.01), presence of papillae (p < 0.05) and quality and quantity of mucosa (p < 0.02) in favor of FOE. CONCLUSIONS: Within the main limitations of sample size and the retrospective study design, both concepts seem to provide clinically acceptable results. CLINICAL RELEVANCE: Bone- and tissue-preserving characteristics regarding the concept of FOE are promising. It could be applicable for socket preservation and subsequent conventional implant placements in an adapted workflow.

4.
J Dent ; 136: 104646, 2023 09.
Artículo en Inglés | MEDLINE | ID: mdl-37527727

RESUMEN

OBJECTIVES: Retaining and restoring severely compromised teeth with subcrestal defect extensions or removing and replacing them using implant-supported crowns (ISC) remains controversial, and economic analyses comparing both strategies remain scarce. We performed a cost-time analysis, comparing the expenditures for retaining "unrestorable" teeth using forced orthodontic extrusion and restoration (FOE) versus extraction and ISC, in a clinical prospective cohort study. METHODS: Forty-two patients (n = 21 per group) were enrolled from clinical routine at a university into this study. Direct medical and indirect costs (opportunity costs) were assessed for all relevant steps (initial care, active care, restorative care, supportive care) using the private payer's perspective in German healthcare based on a micro-costing approach and/or national fee items. Statistical comparison was performed with Mann-Whitney-U test. RESULTS: Patients were followed up for at least one year after initial treatment (n = 40). The drop-out rate was 5% (n = 2). Total direct medical costs were higher for ISC (median: 3439.05€) than FOE (median: 1601.46€) with p<0.001. We observed a higher number of appointments (p = 0.002) for ISC (median: 14.5) in comparison to FOE (median: 12), while cumulatively, FOE patients spent more time in treatment (median: 402.5 min) in comparison to ISC (median: 250 min) with p<0.001, resulting in comparable opportunity costs for both treatment groups (FOE: 304.50€; ISC: 328.98€). CONCLUSIONS: ISC generated higher costs than FOE. More in-depth and long-term exploration of cost-effectiveness is warranted. CLINICAL SIGNIFICANCE: ISCs were associated with higher initial medical costs and required more appointments than the restoration of severely compromised teeth after FOE. Treatment time was higher for patients with FOE, resulting in similar opportunity costs for both treatment approaches. Future research needs to investigate long-term cost-effectiveness.


Asunto(s)
Implantes Dentales de Diente Único , Gastos en Salud , Humanos , Estudios Prospectivos , Análisis Costo-Beneficio , Diente Molar , Coronas
5.
Clin Oral Investig ; 27(9): 5587-5594, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37498335

RESUMEN

OBJECTIVES: Clinical data on retaining extensively damaged teeth using forced orthodontic extrusion followed by restorative rehabilitation are scarce, and economic evaluations are basically absent. A health economic evaluation of this method was performed based on a clinical study. MATERIALS AND METHODS: In a convenience sample of individuals recruited from routine care, extensively damaged teeth were orthodontically extruded prior to restoration. Patients were followed up for up to 6 years. The health outcome was tooth retention time. Direct medical, non-medical, and indirect initial and follow-up costs were estimated using the private payer's perspective in German healthcare. Association of initial direct medical treatment costs and cofounding variables was analyzed using generalized linear models. Success and survival were secondary outcomes. RESULTS: A total of 35 teeth in 30 patients were followed over a mean ± SD of 49 ± 19 months. Five patients (14%) dropped out during that period. Median initial costs were 1941€ (range: 1284-4392€), median costs for follow-up appointments were 215€ (range: 0-5812€), and median total costs were 2284€ (range: 1453 to 7109€). Endodontic re-treatment and placement of a post had a significant impact on total costs. Three teeth had to be extracted and in three patients orthodontic relapse was observed. The survival and success rates were 91% and 83%, respectively. CONCLUSIONS: Within the limitations of this clinical study, total treatment costs for orthodontic extrusion and subsequent restoration of extensively damaged teeth were considerable. Costs were by large generated initially; endodontic and post-endodontic therapies were main drivers. Costs for retreatments due to complications were limited, as only few complications arose. CLINICAL RELEVANCE: The restoration of extensively damaged teeth after forced orthodontic extrusion comes with considerable initial treatment costs, but low follow-up costs. Overall and over the observational period and within German healthcare, costs are below those for tooth replacement using implant-supported crowns. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: DRK S00026697).


Asunto(s)
Coronas , Extrusión Ortodóncica , Humanos , Análisis Costo-Beneficio , Atención a la Salud , Extrusión Ortodóncica/métodos , Reimplante Dental
6.
Int J Comput Dent ; 26(2): 137-148, 2023 May 26.
Artículo en Inglés | MEDLINE | ID: mdl-36607263

RESUMEN

AIM: To compare the planned implant position (PIP) with the transferred implant position (TIP) after fully guided implant placements in single-tooth gaps. MATERIALS AND METHODS: Dental implant placements were planned using two different implant systems (Camlog Screw-Line [C-SL] and Straumann Bone Level Tapered [S-BLT]), and two different planning software programs (SMOP and coDiagnostiX). All implants were placed according to fully guided protocols, and intraoral scans were performed intraoperatively. For the comparison of PIP and TIP, scan data were imported to Geomagic Control X (GCX) software and accuracies were evaluated. Deviations were reported in a coordinate system (x- [mesiodistal], y- [vestibulo-oral], and z- [vertical] axis) at entry points and apices. Total deviations, including angular deviations, were calculated with GCX. For statistical analysis, the level of significance was set to P < 0.05. RESULTS: Twenty-six patients received 26 implants. Mean 3D deviation at the implant's entry point was 0.61 mm ± 0.28 for C-SL and 0.63 mm ± 0.24 for S-BLT. For the implant's apex, mean 3D deviation of 0.96 mm ± 0.41 was documented for C-SL and 1.04 mm ± 0.34 for S-BLT. Mean angular deviation was 2.58 degrees ± 1.40 for C-SL and 2.89 degrees ± 1.12 for S-BLT. Statistical analysis revealed no significant differences between implant systems, but showed significant deviations regarding the z-axis, both at entry point and apex (P < 0.05). CONCLUSIONS: Fully guided implant placements in single-tooth gaps provide accurate results. Due to significant vertical deviations, reevaluation of both drilling and insertion depths prior to implant installation should be considered. Maintenance of 1.5- to 2-mm safety distances to critical structures was confirmed.


Asunto(s)
Implantes Dentales , Cirugía Asistida por Computador , Humanos , Implantación Dental Endoósea/métodos , Tomografía Computarizada de Haz Cónico , Estudios Prospectivos , Diseño Asistido por Computadora , Imagenología Tridimensional
7.
J Prosthet Dent ; 129(1): 61-68, 2023 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-36535882

RESUMEN

STATEMENT OF PROBLEM: Clinical data on orthodontic extrusion to restore teeth deemed unrestorable because of their defect size are scarce. It remains unclear for which defects forced orthodontic extrusion and tooth retention is preferred to extraction. PURPOSE: The purpose of this pilot clinical study was to investigate the survival, frequency, and type of complications of extensively damaged teeth requiring single-crown restorations after forced orthodontic extrusion. MATERIAL AND METHODS: Participants were recruited from consecutive patients in need of restorative treatment of extensively damaged teeth at a university clinic. The teeth were orthodontically extruded to reestablish the biologic width and to ensure a 2-mm ferrule preparation before restoration. The primary endpoint was restoration success and survival. At recall, survival was defined as the tooth being in situ and success as a symptom-free tooth with an intact, caries-free restoration and with physiological pocket probing depths, no signs of intrusion, ankylosis, root resorption, or periapical radiolucency. Recalls were performed every 6 months; the outcome was assessed by radiographic and clinical evaluation after up to 5 years of clinical service. Quantitative parameters were described with mean values and standard deviations. RESULTS: Thirty-four participants were assessed for eligibility and enrolled (mean ±standard deviation age: 53.4 ±18.9 years). Four participants were premature dropouts. Data were analyzed for 35 teeth in 30 participants. The amount of extrusion varied between 2 and 6 mm (mean ±standard deviation 3.4 ±0.9 mm). The mean duration of extrusion was 18.9 ±12.6 days and the mean duration of retention was 126.94 ±88.1 days. The mean ±standard deviation crown-to-root ratio after treatment was 0.8 ±0.1 (range: 0.5 to 1.0). Three participants exhibited orthodontic relapse before restoration. Teeth were successfully restored after repeated extrusion. After a mean observation period of 3.3 years (range: 1 to 5.2 years), 29 of 31 teeth were still in situ. Two teeth were fractured, and 4 participants were not available for recall. Thus, the survival rate was 94%. No resorption or periapical translucencies were observed radiographically. Clinical examinations revealed physiological probing depths and absence of ankyloses. One tooth presented with marginal bone loss. The most frequent type of complication was orthodontic relapse at recall (n=3). A total of 84% of teeth were considered a success. CONCLUSIONS: Forced orthodontic extrusion allowed for the restoration of anterior and premolar teeth deemed as nonrestorable because of their defect size. Tooth retention of extensively damaged teeth and their use as abutments for single-crown restorations can be recommended.


Asunto(s)
Extrusión Ortodóncica , Corona del Diente , Humanos , Adulto , Persona de Mediana Edad , Anciano , Extrusión Ortodóncica/métodos , Diente Premolar , Coronas , Recurrencia
8.
J Clin Med ; 11(24)2022 Dec 17.
Artículo en Inglés | MEDLINE | ID: mdl-36556111

RESUMEN

In cases of severely compromised teeth, dental practitioners are confronted with the therapeutic decision of whether to restore a tooth or replace it with an implant. Comparative scientific evidence on patient perception of both treatment approaches is scarce. The subject of this prospective clinical study was to compare oral health-related quality of life (OHRQoL) between two treatment groups: restoration of severely destroyed teeth after orthodontic extrusion (FOE) versus tooth extraction and implant-supported single crown restoration (ISC). A self-selected trial was performed with 21 patients per group. OHRQoL was assessed with the aid of the Oral Health Impact Profile (OHIP-G49) at different time intervals: before treatment (T1), after treatment (T2), after restoration (T3) and at recall (T4). Overall, OHIP scores improved from baseline to follow-up for both concepts with no significant differences between groups. There were no significant differences in subscales between FOE and ISC at T1, T3 and T4. In terms of functional limitations (p = 0.003) and physical disability (p = 0.021), patients in the FOE group temporarily exhibited lower OHRQoL at T2 in comparison to the ISC group. However, at baseline, after final restoration and at recall, the study demonstrates the same level of OHRQoL for both treatment concepts.

9.
J Dent ; 125: 104265, 2022 10.
Artículo en Inglés | MEDLINE | ID: mdl-35995082

RESUMEN

OBJECTIVES: To compare the planned (PIP) and transferred implant position (TIP) after dental implant placement in single-tooth gaps utilizing dynamic computer-assisted implant surgery (dCAIS). METHODS: Five pairs of artificial jaws (n = 5) with four single tooth gaps in FDI (Fédération Dentaire Internationale) regions 16, 25, 36 and 44 were manufactured via injection molding technique. Cone beam computed tomographies (CBCTs) were made and digital implant planning of twenty implants (n = 20) was performed with a dynamic navigation system (DNS, Navident, ClaroNav, Toronto, Canada). After guided drilling and manual implant placement, post-operative CBCTs were made. Global deviations at entry point (two-dimensional, 2D), apex (three-dimensional, 3D), apex (vertical, V) and angulation (in degrees, °) were calculated by DNS software. For statistical analysis, level of significance was set to p < 0.05. RESULTS: Mean deviation at the implants entry point (2D) was 0.78 ± 0.45 mm (range: 0.10-1.63 mm). For the implants apex (3D) and the implants apex (V) deviations were 1.08 ± 0.50 mm (range: 0.33-2.10 mm) and 0.32 ± 0.22 mm (range: 0.02-0.90 mm), respectively. The median angular deviation (°) was 2.81 ± 2.29° (range: 0.56-9.58°). Statistically significant differences (p < 0.05) were found regarding apex (3D), apex (V), and angulation (°) comparing I.-IV. quadrants. CONCLUSIONS: Using the investigated dCAIS seems to provide satisfactory results regarding TIP in single-tooth gaps in vitro. Due to documented deviations, a safety distance of more than 2 mm should be respected while implant planning in DNS software. CLINICAL SIGNIFICANCE: The investigated DNS seems to be reliant in transferring PIP with acceptable deviations in vitro.


Asunto(s)
Implantes Dentales , Cirugía Asistida por Computador , Diseño Asistido por Computadora , Tomografía Computarizada de Haz Cónico , Implantación Dental Endoósea/métodos , Imagenología Tridimensional , Proyectos Piloto
10.
Quintessence Int ; 53(6): 522-531, 2022 May 11.
Artículo en Inglés | MEDLINE | ID: mdl-35119237

RESUMEN

Maintaining and restoring teeth exhibiting subgingival or even subcrestal defect extensions represent a common problem in daily practice. Such teeth are often deemed "unrestorable" due to a significant hard tissue loss and defect locations violating the biologic width. In order to achieve a sufficient 2-mm-ferrule design and reestablish the biologic width, both surgical crown lengthening and orthodontic extrusion have been suggested. However, surgical crown lengthening has a negative effect on the attachment level of adjacent teeth as well as esthetic disadvantages particularly in the esthetic zone. Therefore, orthodontic extrusion might be considered as a valid therapeutic alternative since gingival architecture is maintained. While most orthodontic appliances are too complex for daily application, forced orthodontic extrusion by means of the Tissue Master Concept might be a cost- and time-effective approach due to advances in adhesive and computer-assisted dentistry. This clinical case series illustrates the methodology of the rather straightforward Tissue Master Concept in specific clinical situations that may occur in clinical routine.


Asunto(s)
Productos Biológicos , Fracturas de los Dientes , Coronas , Humanos , Extrusión Ortodóncica , Corona del Diente
11.
Clin Oral Investig ; 26(1): 849-861, 2022 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-34241707

RESUMEN

OBJECTIVES: To evaluate long-term survival and success rates of conventionally cemented partial-coverage crowns (PCCs) manufactured from high noble metal alloys (hn). MATERIAL AND METHODS: Restoration-, periodontal- and tooth-related criteria on patients, restored with a single or multiple conventionally cemented hnPCCs in a private dental office were collected from existing patient records. With regard to semi-annual follow-ups, data of the most recent clinical evaluations were considered. Kaplan-Meier and log-rank tests were used for statistical analyses. Level of significance was set at p ≤ .05. RESULTS: Between 09/1983 and 09/2009, 1325 hnPCCs were conventionally cemented on 1325 teeth in 266 patients (mean age: 44.5 ± 10.7 years). Due to various reasons, 81 hnPCCs showed complications, documenting a success rate of 93.9% after a mean observation period of 18.8 ± 5.7 years. Of these, additional 14 restorations were counted as survival, resulting in a survival rate of 94.9%. Most frequent complications were periodontal issues (n = 29, 35.8%). Significantly higher success rates were documented for hnPCCs of patients aged between 37 and 51 years (p = .012). CONCLUSION: Partial-coverage crowns from high noble metal alloys showed excellent survival and success rates after a mean observation period of 18.8 ± 5.7 years. Higher patient age was one of the risk factors. CLINICAL RELEVANCE: According to the results of this study, hnPCCs still represent an excellent therapeutic option-even in modern dentistry.


Asunto(s)
Porcelana Dental , Aleaciones de Cerámica y Metal , Adulto , Aleaciones , Coronas , Fracaso de la Restauración Dental , Humanos , Persona de Mediana Edad , Estudios Retrospectivos
12.
Int J Comput Dent ; 24(4): 393-403, 2021 Dec 21.
Artículo en Inglés | MEDLINE | ID: mdl-34931775

RESUMEN

AIM: To investigate retentive forces (RFs) of CAD/CAM-milled and conventionally cast secondary crowns (SCs) after artificial aging in an in vitro study. MATERIALS AND METHODS: Forty artificial premolars were manufactured and provided with 40 primary crowns (PCs) milled from a high noble metal alloy. SCs were fabricated from the same alloy. Ten SCs were produced with the help of a tactile scanning method (group A), 10 with the help of a photo-optical scan (spray; group B), 10 with the help of a photo-optical scan (acrylic dye; group C), and 10 using a conventional casting technique (group D). Cycles of separation were performed and RFs were measured at baseline and after 5,000 and 10,000 cycles. Surfaces were examined under a scanning electron microscope (SEM). Statistical analysis was conducted at a significance level of P ≤ 0.05. RESULTS: Group D showed the highest median RFs with respective interquartile ranges (IQRs) - baseline: 7.0(2.5) N; 5,000 cycles: 5.5(2.0) N; 10,000 cycles: 5.4(1.5) N compared with groups A, B, and C - baseline: 5.2(8.4)/3.4(11.3)/1.3(1.5) N; 5,000 cycles: 1.8(0.8)/2.1(1.7)/1.0(1.3) N; 10,000 cycles: 1.9(1.6)/2.4(2.5)/1.0(1.4) N, respectively. In contrast to groups A, B, and C, group D did not gain RF when RF values were compared after 5,000 and 10,000 cycles. The loss of RF between baseline (7.0 N) and after 10,000 cycles (5.4 N) was significant only for group D (P = 0.007), but not for groups A, B, and C. CONCLUSION: Both CAD/CAM-milled and conventionally cast SCs from a high noble metal alloy can provide sufficient RF after 10,000 cycles of artificial aging. However, groups A, B, and C showed constantly lower RF values compared with group D.


Asunto(s)
Diseño Asistido por Computadora , Coronas , Aleaciones , Diseño de Prótesis Dental , Aleaciones de Oro , Humanos , Ensayo de Materiales
13.
J Clin Med ; 9(8)2020 Jul 23.
Artículo en Inglés | MEDLINE | ID: mdl-32717843

RESUMEN

The objective was to investigate clinical and radiological outcomes of rehabilitations with root-analogue implants (RAIs). Patients restored with RAIs, supporting single crowns or fixed dental prostheses, were recruited for follow-up examinations. Besides clinical and esthetical evaluations, X-rays were taken and compared with the records. Patients were asked to evaluate the treatment using Visual Analogue Scales (VAS). For statistical analyses, mixed linear models were used. A total of 107 RAIs were installed in one dental office. Of these, 31 were available for follow-up examinations. For those remaining, survival has been verified via phone. RAIs were loaded after a mean healing time of 6.6 ± 2.5 months. 12.1 ± 6.9 months after loading, a mean marginal bone loss (MBL) of 1.20 ± 0.73 mm was measured. Progression of MBL significantly decreased after loading (p = 0.013). The mean pink and white esthetic score (PES/WES) was 15.35 ± 2.33 at follow-up. A survival rate of 94.4% was calculated after a mean follow-up of 18.9 ± 2.4 months after surgery. Immediate installation of RAIs does not seem to reduce MBL, as known from the literature regarding screw-type implants, and might not be recommended for daily routine. Nevertheless, they deliver esthetically satisfying results.

SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA