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1.
Phys Rev Lett ; 93(2): 022302, 2004 Jul 09.
Artículo en Inglés | MEDLINE | ID: mdl-15323906

RESUMEN

Production of Lambda and Antilambda hyperons was measured in central Pb-Pb collisions at 40, 80, and 158A GeV beam energy on a fixed target. Transverse mass spectra and rapidity distributions are given for all three energies. The Lambda/pi ratio at midrapidity and in full phase space shows a pronounced maximum between the highest BNL Alternating Gradient Synchrotron and 40A GeV CERN Super Proton Synchrotron energies, whereas the Lambda/pi ratio exhibits a monotonic increase.

2.
Acta Anaesthesiol Belg ; 50(2): 71-6, 1999.
Artículo en Inglés | MEDLINE | ID: mdl-10418645

RESUMEN

We studied nociception-associated arousal following laryngoscopy and intubation in patients scheduled for elective open heart surgery, using EEG power spectra and hemodynamics. Either fentanyl (7 micrograms/kg; n = 30) or sufentanil (1 microgram/kg; n = 30) were given in a randomized fashion to induce anesthesia in heavily premedicated patients, followed by pancuronium bromide (100 micrograms/kg). EEG-power spectra (delta, theta, alpha, beta) as well as mean arterial blood pressure (MAP) and heart rate (HF) were measured at the following end-points: before the induction of anesthesia (control), 1 and 10 minutes after laryngoscopy and intubation (L & I). Linear regression analysis was computed to determine which of the EEG power spectra was most sensitive to detect insufficient blockade of nociceptive-related arousal when correlated with haemodynamics. In the fentanyl group the change in HF closely correlated with the decrease of power in the slow delta- and theta-domain (r2 = 0.98 and r2 = 0.89 respectively) of the EEG. The change in MAP also closely correlated with a decrease in the slow delta- and theta-domain (r2 = 0.97 and r2 = 0.99 respectively). There was little correlation in regard to spectral edge frequency (SEF) and HF and MAP changes (r2 = 0.36 and r2 = 0.12 respectively). In the sufentanil group the change in HF correlated closely with an increase of power in the fast alpha and a decrease in the slow theta-domain (r2 = 0.91 and r2 = 0.98 respectively) of the EEG. The changes in MAP closely correlated with an increase in the fast alpha-band a decrease in the slow theta-domain (r2 = 0.98 and r2 = 0.73 respectively). Also there was little correlation of SEF with HF and MAP changes (r2 = 0.09 and r2 = 0.02 respectively). Among the EEG-spectra, reduction of power in the slow delta- and theta-bands are the most sensitive parameters to determine insufficient antinociception of opioids commonly used for the induction in cardiac anesthesia. Increase of power in the alpha-band seems to be closely correlated with cortical reactivation and reduction of hypnosis, while a reduction of power especially in the deltabut more so in the theta-band of the EEG reflects nociception related arousal.


Asunto(s)
Anestésicos Intravenosos/administración & dosificación , Presión Sanguínea/efectos de los fármacos , Electroencefalografía/efectos de los fármacos , Fentanilo/administración & dosificación , Frecuencia Cardíaca/efectos de los fármacos , Intubación Intratraqueal , Laringoscopía , Sufentanilo/administración & dosificación , Ritmo alfa/efectos de los fármacos , Nivel de Alerta/efectos de los fármacos , Puente de Arteria Coronaria , Ritmo Delta/efectos de los fármacos , Femenino , Implantación de Prótesis de Válvulas Cardíacas , Humanos , Modelos Lineales , Masculino , Persona de Mediana Edad , Válvula Mitral/cirugía , Fármacos Neuromusculares no Despolarizantes/administración & dosificación , Nociceptores/efectos de los fármacos , Pancuronio/administración & dosificación , Medicación Preanestésica , Estudios Prospectivos , Ritmo Teta/efectos de los fármacos
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