RESUMEN
Reed's syndrome (RS) is a rare autosomal-dominant disorder characterised by multiple cutaneous and uterine leiomyomas, with a strong tendency for renal cell carcinoma (RCC) development. A woman in her 50s, who had previously undergone total abdominal hysterectomy due to multiple uterine leiomyomas, presented with painful nodules on her trunk and right arm for the past 6 years. These nodules were confirmed as leiomyomas through histopathology. Diagnosis of RS was established through clinicopathological correlation and positive family history, particularly her mother's. Early-onset uterine leiomyomas in patients with a similar family history should raise suspicion for RS, necessitating vigilant long-term follow-up. RCC detection requires mandatory renal imaging. Screening family members and providing genetic counselling are crucial.
Asunto(s)
Carcinoma de Células Renales , Neoplasias Renales , Leiomiomatosis , Síndromes Neoplásicos Hereditarios , Neoplasias Cutáneas , Neoplasias Uterinas , Femenino , Humanos , Carcinoma de Células Renales/genética , Neoplasias Uterinas/diagnóstico por imagen , Neoplasias Uterinas/cirugía , Leiomiomatosis/diagnóstico por imagen , Leiomiomatosis/cirugía , Neoplasias Cutáneas/diagnóstico , Neoplasias Cutáneas/cirugía , Neoplasias Cutáneas/genética , Síndromes Neoplásicos Hereditarios/diagnóstico , Síndromes Neoplásicos Hereditarios/cirugía , Síndromes Neoplásicos Hereditarios/patología , Neoplasias Renales/genética , Fumarato Hidratasa/genéticaAsunto(s)
COVID-19 , Herpes Zóster , Herpes Zóster/complicaciones , Herpes Zóster/diagnóstico , Herpesvirus Humano 3 , Humanos , Piel , Nervio TrigéminoRESUMEN
Pityriasis rosea (PR) is a common papulosquamous disorder that may be related to primary infection or endogenous reactivation of human herpesvirus 7 and 6. Based on morphology, distribution, and size of lesions, several atypical variants of PR have been described. PR following the lines of Blaschko represents an atypical variant that has seldom been described in the literature. Here, we describe a child with diabetes who developed PR in a symmetrical, blaschkolinear configuration.
Asunto(s)
Herpesvirus Humano 7 , Pitiriasis Rosada , Niño , Familia , Humanos , Pitiriasis Rosada/diagnósticoAsunto(s)
Melanoma , Trastornos de la Pigmentación , Neoplasias Cutáneas , Dermoscopía , Humanos , PigmentaciónRESUMEN
Papulonecrotic tuberculid represents a hypersensitivity reaction to Mycobacterium tuberculosis or its products that disseminate through hematogenous route to the skin from an internal tuberculous focus. It is characterized by recurrent eruptions of asymptomatic, dusky red papules, which undergo ulceration and crusting, and eventually heal after a few weeks with varioliform scarring. Although it most commonly involves extragenital sites, isolated glans penis involvement has been reported very rarely.