Compressive strength and fluoride release profile of a glass ionomer cement reinforced with silver-hydroxyapatite-silica hybrid nanoparticles: An in vitro study.

OBJECTIVES: This study aimed to prepare a glass ionomer (GI) cement reinforced with silver-hydroxyapatite-silica (Ag/HA/Si) hybrid nanoparticles and assess its compressive strength and fluoride release profile. MATERIAL AND METHODS: In this in vitro, experimental study, 60 cylindrical specimens were fabricated with 4mm diameter and 6mm height in 6 groups (n=10) using BracePaste composite, GC Fuji II LC pure RMGI, and RMGI reinforced with 0.1wt%, 0.5wt%, 1wt%, and 2wt% Ag/HA/Si hybrid nanoparticles. The specimens were subjected to compressive force in a universal testing machine to measure their compressive strength (MPa). To assess their fluoride release profile, discs with 3mm diameter and 2mm thickness were fabricated from Fuji II LC pure resin-modified glass ionomer (RMGI), and RMGI with 0.1wt%, 0.5wt%, 1wt%, and 2wt% hybrid nanoparticles, and the concentration of released fluoride was measured by a digital ion-selective electrode. Data were analysed by ANOVA and Scheffe test (alpha=0.05). RESULTS: The compressive strength was 114.14MPa for BracePaste composite, and 97.14, 97.84, 100.65, 109.5, and 89.33MPa for GI groups with 0%, 0.1%, 0.5%, 1% and 2% hybrid nanoparticles, respectively, with no significant difference among them (P=0.665). Addition of 1% (0.21±0.07µg/mL, P=0.029) and 2% (0.45±0.22µg/mL, P=0.000) hybrid nanoparticles to RMGI significantly increased the amount of released fluoride, compared with the control group (0.09±0.03µg/mL). CONCLUSIONS: Addition of Ag/HA/Si hybrid nanoparticles to RMGI in the tested concentrations had no significant effect on its compressive strength but addition of 1wt% and 2wt% concentrations of Ag/HA/Si hybrid nanoparticles increased its fluoride release potential.

Effect of incorporating silica-hydroxyapatite-silver hybrid nanoparticles into the resin-modified glass ionomer on the adhesive remnant index score and shear bond strength of orthodontic metal brackets: An in vitro study.

OBJECTIVES: This study aimed to assess the effect of addition of silica-hydroxyapatite-silver (Si-HA-Ag) hybrid nanoparticles to light-cure glass ionomer (GI) on shear bond strength (SBS) of metal brackets bonded with this adhesive and the adhesive remnant index (ARI) score. MATERIAL AND METHODS: In this in vitro experimental study, 50 sound extracted premolars were assigned to 5 groups (n=10) for orthodontic metal bracket bonding with BracePaste® composite, Fuji ORTHO™ pure resin modified GI (RMGI), and RMGI reinforced with 2wt%, 5wt% and 10wt% Si-HA-Ag nanoparticles. The SBS of brackets was measured by a universal testing machine. Debonded specimens were inspected under a stereomicroscope at×10 magnification to determine the ARI score. Data were analyzed by one-way ANOVA, Scheffe test, Chi-square test, and Fisher's exact test (alpha=0.05). RESULTS: The maximum mean SBS was recorded in BracePaste® composite followed by 2% RMGI, 0% RMGI, 5% RMGI and 10% RMGI. Only the difference between the BracePaste® composite and 10% RMGI was significant in this regard (P=0.006). The groups were not significantly different regarding the ARI scores (P=0.665). All the SBS values were within the clinically acceptable range. CONCLUSION: Addition of 2wt% and 5wt% Si-HA-Ag hybrid nanoparticles to RMGI as orthodontic adhesive caused no significant change in SBS of orthodontic metal brackets while addition of 10wt% hybrid nanoparticles significantly decreased the SBS. Nonetheless, all the SBS values were within the clinically acceptable range. Addition of hybrid nanoparticles had no significant effect on the ARI score.