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1.
J Clin Microbiol ; 62(6): e0034224, 2024 Jun 12.
Artículo en Inglés | MEDLINE | ID: mdl-38785447

RESUMEN

A prior analysis suggested that wound swab culture (WSC) results were driving unnecessary antibiotic use in patients who were not already receiving treatment. As a quality-improvement initiative, our laboratory introduced an "exception-reporting" protocol on 1 March 2023, whereby typical wound pathogens susceptible to recommended empiric therapy (flucloxacillin/cefalexin) were not reported, and a comment was provided, stating no significant resistant organisms had been detected. Full results were available to clinicians on request. Cultures falling outside protocol criteria were reported in the standard fashion. This analysis sought to assess the effect of exception-reporting on post-report antibiotic initiation (PRAI). All community WSC results were matched to antibiotic dispensing records from October 2021 to December 2023. Sampling without treatment pre-report was termed "test and wait" (TaW). Following TaW, PRAI was identified if antibiotics were started within 5 days post-report. There were 1,819 and 764 WSCs received in the pre-change and post-change periods, respectively, where an initial TaW approach had been taken and an organism eligible for exception-reporting had been isolated. In the post-change period, 407 (53.3%) met the criteria and were exception-reported. PRAI occurred in 901 (49.5%) pre-change samples, compared to 102 (25.1%, P < 0.01) with exception-reporting. There was no detectable increase in hospitalization or repeat WSC collection in the 30 days following exception-reporting. Exception-reporting was associated with a markedly reduced proportion of patients being initiated on antibiotics following WSC where an organism had been isolated. The naming of organisms in reports appears to drive unnecessary antibiotic prescribing in many patients. These results require confirmation in other jurisdictions. IMPORTANCE: Wound swab culture is a high-volume test performed in clinical microbiology laboratories. In this analysis, we have shown that an alternative approach to reporting positive wound swab cultures has resulted in a large reduction in post-report antibiotic initiation, suggesting that the current standard method of reporting generates considerable unnecessary antibiotic use. If these findings are replicated elsewhere, wider adoption of this reporting would represent an opportunity for many clinical microbiology laboratories to have a significant impact on community antimicrobial stewardship.


Asunto(s)
Antibacterianos , Infección de Heridas , Humanos , Antibacterianos/uso terapéutico , Infección de Heridas/microbiología , Infección de Heridas/tratamiento farmacológico , Infección de Heridas/diagnóstico , Femenino , Masculino , Anciano , Persona de Mediana Edad , Adulto , Programas de Optimización del Uso de los Antimicrobianos , Manejo de Especímenes/métodos , Anciano de 80 o más Años
2.
N Z Med J ; 137(1594): 31-42, 2024 May 03.
Artículo en Inglés | MEDLINE | ID: mdl-38696830

RESUMEN

AIM: Our antimicrobial guidelines (AGs) were changed in 2021 to recommend once-daily ceftriaxone in place of three-times-daily cefuroxime as preferred cephalosporin. This analysis sought to assess the effects of this on incidence of Clostridioides difficile infection (CDI), third-generation cephalosporin-resistant Enterobacterales (3GCR-E) and resource utilisation. METHOD: Before and after analysis of 30-day CDI and 3GCR-E incidence following receipt of cefuroxime/ceftriaxone pre- and post-AG change. Total nursing time and waste production relating to cefuroxime/ceftriaxone delivery were calculated pre- and post-change. RESULTS: CDI incidence was 0.6% pre- and 1.0% post-change (adjusted odds ratio [aOR] 1.44, p=0.07) and 3GCR-E incidence 3.5% and 3.1% (aOR 0.90, p=0.33). Mean per-quarter estimated nursing administration time decreased from 2,065 to 1,163 hours (902 nurse-hour reduction) and antibiotic-related waste generation from 1,131kg to 748kg (383kg reduction). Overall days of therapy per-quarter of cefuroxime/ceftriaxone were unchanged between periods. CONCLUSION: This simplification of our AG from a three-times-daily to a once-daily antibiotic resulted in considerable savings for our hospital (roughly 1.7 full-time equivalent nurses and over a tonne of waste yearly), with no significant increases in CDI or 3GCR-E. The impact of dosing schedules on non-antibiotic-spectrum factors, such as nursing time and resource usage, is worthy of consideration when designing AGs.


Asunto(s)
Antibacterianos , Programas de Optimización del Uso de los Antimicrobianos , Ceftriaxona , Cefuroxima , Humanos , Cefuroxima/uso terapéutico , Cefuroxima/administración & dosificación , Antibacterianos/uso terapéutico , Antibacterianos/administración & dosificación , Ceftriaxona/uso terapéutico , Ceftriaxona/administración & dosificación , Masculino , Femenino , Infecciones por Clostridium/tratamiento farmacológico , Infecciones por Clostridium/epidemiología , Persona de Mediana Edad , Incidencia , Anciano , Infecciones por Enterobacteriaceae/tratamiento farmacológico , Infecciones por Enterobacteriaceae/epidemiología , Guías de Práctica Clínica como Asunto , Esquema de Medicación
3.
J Antimicrob Chemother ; 79(2): 334-338, 2024 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-38101947

RESUMEN

BACKGROUND: In patients without ethnicity risk factors for acute rheumatic fever (ARF), our local guidelines recommend limiting antibiotic use following a positive throat swab culture (TSC). If symptoms are severe, a 5-7 day course is recommended. Despite this, most local patients with a positive TSC for group A Streptococcus (GAS) or Streptococcus dysgalactiae subsp. equisimilis (SDSE) were being prescribed 10 days of antibiotics. In response, we added comments to positive TSC reports recommending shorter treatment durations in those without ARF risk factors. No other antimicrobial stewardship initiatives were implemented. OBJECTIVES: To assess the effect of these comments on antibiotic course duration after positive TSC. METHODS: All community TSC results from 1 October 2021 to 31 March 2023 (1 year pre- to 6 months post-change) were matched to antibiotic dispensing data. Patients who had been empirically dispensed an antibiotic prior to the culture report were excluded. The outcome of interest was the antibiotic duration dispensed in the 5 day period after the TSC report. RESULTS: Following introduction of the comments, median course duration reduced from 10 (IQR 5-10) to 7 days (IQR 0-10; P < 0.01) and from 7 (IQR 0-10) to 0 days (IQR 0-5; P < 0.01) following GAS- and SDSE-positive TSC, respectively, in those without ARF risk factors. The percentage of people receiving 10 days of antibiotics decreased from 63.0% to 37.0% (P < 0.01) and 41.2% to 14.6% (P < 0.01) for GAS and SDSE, respectively. CONCLUSIONS: The introduction of comments providing direct prescribing advice to requestors appears to have been highly effective at improving guideline-compliant prescribing following positive TSC report.


Asunto(s)
Faringitis , Fiebre Reumática , Infecciones Estreptocócicas , Streptococcus , Humanos , Faringitis/tratamiento farmacológico , Faringe , Streptococcus pyogenes , Antibacterianos/uso terapéutico , Infecciones Estreptocócicas/diagnóstico , Infecciones Estreptocócicas/tratamiento farmacológico
4.
J Antimicrob Chemother ; 78(11): 2715-2722, 2023 11 06.
Artículo en Inglés | MEDLINE | ID: mdl-37712940

RESUMEN

OBJECTIVES: Positive culture results from non-sterile sites (NSSs) are poorly predictive of clinical infection. Despite this, these results are often interpreted as an indication for antibiotics, even in patients with limited signs of infection. We sought to quantify the influence of NSS culture results on post-report antibiotic initiation (PRAI) in patients who had not been started on antibiotics pre-report. METHODS: All community wound/skin swab and sputum cultures were matched to antibiotic dispensing records from February 2017 to July 2022. Prescribing behaviour was assessed pre- and post-report. Sampling without treatment pre-report was termed 'test-and-wait' (TaW). Following TaW, PRAI was identified if antibiotics were started within 5 days post-report. RESULTS: There were 65 480 wound/skin swabs and 8126 sputum samples, with TaW occurring in 21 740 (35.1%) and 4185 (54.4%), respectively. Following a TaW approach PRAI occurred in 43.3% when an organism was reported, versus 10.8% (P < 0.01) for a 'no growth' report for wound/skin swabs. For the same comparison with sputum, PRAI occurred in 47.9% versus 10.8% (P < 0.01). On multivariate analysis reporting an organism remained strongly associated with PRAI. CONCLUSIONS: Reporting an organism in those not already on antibiotics was strongly associated with PRAI. We hypothesize that for many patients TaW suggests limited evidence of infection (i.e. insufficient to justify antibiotic treatment at time of sampling), meaning positive NSS results may be driving a considerable volume of potentially unnecessary antibiotic use. Further study on this topic is required, but strategies to reduce PRAI may offer laboratories an opportunity to meaningfully impact antimicrobial stewardship efforts.


Asunto(s)
Antibacterianos , Programas de Optimización del Uso de los Antimicrobianos , Humanos , Antibacterianos/uso terapéutico , Programas de Optimización del Uso de los Antimicrobianos/métodos
5.
Exp Gerontol ; 174: 112117, 2023 04.
Artículo en Inglés | MEDLINE | ID: mdl-36758648

RESUMEN

Stepping between static and moving surfaces presents a locomotor challenge associated with increased injury frequency and severity in older adults. The current study evaluates younger and older adults' behaviours when overcoming challenges sampling moving walkway and escalator environments. Twelve younger adults (18-40 years, Male = 8) and 15 older adults (60-81 years, Male = 5) were examined using an integration of optoelectronic motion capture and mobile eye-tracking. Participants were investigated approaching and stepping onto a flat conveyor belt (static or moving; with or without surface (demarcation) lines). Specifically, the four conditions were: (i) static surface without demarcation lines; (ii) static surface with demarcation lines; (iii) moving surface without demarcation lines; and (iv) moving surface with demarcation lines. A two (age group) x two (surface-condition) x two (demarcation-condition) linear mixed-model revealed no main or interaction effects (p > .05) for perturbation magnitude, indicating participants maintained successful locomotion. However, different adaptive behaviours were identified between conditions with moving and accuracy demands (e.g., moving surfaces increased step length, demarcations reduced step length). Between subject effects identified differences between age groups. Older adults utilised different behaviours, such as earlier gaze transfer from the final approach walkway step location. Overall, the current study suggests that adaptive behaviours emerge relative to the environment's specific demands and the individual's action capabilities.


Asunto(s)
Locomoción , Caminata , Humanos , Masculino , Anciano
6.
Open Forum Infect Dis ; 9(10): ofac529, 2022 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-36320197

RESUMEN

In a multivariate analysis of 30 574 blood culture (BC) results, BC contamination was associated with only a small increase in antibiotic length of therapy compared to no-growth BCs (difference, 0.36 days [95% confidence interval, .05-.67]; P = .02). Stewardship processes at our institution appear to be effective in reducing the impact of BC contamination.

7.
Iperception ; 13(5): 20416695221116652, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36186610

RESUMEN

Integrating mobile eye tracking and optoelectronic motion capture enables point of gaze to be expressed within the laboratory co-ordinate system and presents a method not commonly applied during research examining dynamic behaviors, such as locomotion. This paper examines the quality of gaze data collected through the integration. Based on research suggesting increased viewing distances are associated with reduced data quality; the accuracy and precision of gaze data as participants (N = 11) viewed floor-based targets at distances of 1-6 m was investigated. A mean accuracy of 2.55 ± 1.12° was identified, however, accuracy and precision measures (relative to targets) were significantly (p < .05) reduced at greater viewing distances. We then consider if signal processing techniques may improve accuracy and precision, and overcome issues associated with missing data. A 4th-order Butterworth lowpass filter with cut-off frequencies determined via autocorrelation did not significantly improve data quality, however, interpolation via Quintic spline was sufficient to overcome gaps of up to 0.1 s. We conclude the integration of gaze and motion capture presents a viable methodology in the study of human behavior and presents advantages for data collection, treatment, and analysis. We provide considerations for the collection, analysis, and treatment of gaze data that may help inform future methodological decisions.

8.
Clin Biomech (Bristol, Avon) ; 99: 105760, 2022 10.
Artículo en Inglés | MEDLINE | ID: mdl-36108472

RESUMEN

BACKGROUND: This study aimed to identify the predictor variables which account for neutral breast position variance using a full independent variable dataset (the gravity-loaded breast position, age and anthropometrics, and magnetic resonance imaging breast composition data), and a simplified independent variable dataset (magnetic resonance imaging breast composition data excluded). METHODS: Breast position (three-dimensional neutral and static gravity-loaded), age, anthropometrics and magnetic resonance imaging breast composition data were collected for 80 females (bra size 32A to 38D). Correlations between the neutral breast position and the gravity-loaded breast position, age, anthropometrics, and magnetic resonance imaging breast composition data were assessed. Multiple linear and multivariate multiple regression models were utilised to predict neutral breast positions, with mean absolute differences and root mean square error comparing observed and predicted neutral breast positions. FINDINGS: Breast volume was the only breast composition variable to contribute as a predictor of the neutral breast position. While ≥69% of the variance in the anteroposterior and mediolateral neutral breast positions were accounted for utilising the gravity-loaded breast position, multivariate multiple regression modelling resulted in mean absolute differences >5 mm. INTERPRETATION: Due to the marginal contribution of breast composition data, a full independent variable dataset may be unnecessary for this application. Additionally, the gravity-loaded breast position, age, anthropometrics, and breast composition data do not successfully predict the neutral breast position. Incorporation of the neutral breast position into breast support garments may enhance bra development. However, further identification of variables which predict the neutral breast position is required.


Asunto(s)
Mama , Gravitación , Mama/diagnóstico por imagen , Femenino , Humanos
9.
N Z Med J ; 135(1559): 53-58, 2022 08 05.
Artículo en Inglés | MEDLINE | ID: mdl-35999781

RESUMEN

AIM: To compare detection of SARS-CoV-2 from paired nasopharyngeal swabs (NPS) and saliva using molecular methods in common use for testing swabs in New Zealand. METHOD: Samples from individuals testing positive for SARS-CoV-2 in Auckland, Wellington and Dunedin were tested at the local laboratories using methods previously established for these sample types. RESULTS: One hundred and ninety-six paired samples from unique individuals were tested, with 46 (23%) positive from either sample type, of which 43/46 (93%) tested positive from NPS, and 42/46 (91%) from saliva, indicating no significant difference in performance between sample types (p=0.69). The average Δ Ct between saliva and nasopharyngeal swabs overall across the sample set was 0.22 cycles, indicating excellent concordance; however, the difference between NPS and saliva collected from the same individual was quite variable with up to 19 cycles difference between the sample types. CONCLUSION: We found that saliva is an equivalent sample type to nasopharyngeal swab for the detection of SARS-CoV-2 in our laboratories using multiple assay combinations and is suitable for use as a diagnostic and surveillance test for selected groups of individuals.


Asunto(s)
COVID-19 , Ácidos Nucleicos , COVID-19/diagnóstico , Técnicas de Laboratorio Clínico/métodos , Humanos , Nasofaringe , Nueva Zelanda , SARS-CoV-2/genética , Saliva , Manejo de Especímenes/métodos
10.
Ergonomics ; 64(3): 410-425, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-32981459

RESUMEN

Breast movement reduction (%) measures breast support and sports bra performance, however limited evidence exists on the sports bra characteristics which affect it. This study investigated breast movement reduction achieved by 98 sports bras, the categorisation of support levels, and the characteristics that contribute. Each bra was tested on ∼12 females (total n = 77). Relative breast position was recorded during sports bra and bare-breasted running, and breast movement reduction calculated; low, medium, high breast support tertiles were identified and compared to brand-classified support levels. Ten bra characteristics were identified, and regressions determined which characteristics contributed to performance. Breast movement reduction ranged from 36% to 74%; 69% of bras marketed as high support were in the high support tertile (>63%). Encapsulation style, padded cups, nylon, adjustable underband and high neck drop accounted for 37.1% of breast movement reduction variance. Findings facilitate high performance sports bra development and inform consumer choice. Practitioner summary: Little is known about the biomechanical breast support which sports bras actually provide. This original research facilitates high performance sports bra development, and helps inform consumer choice, by identifying the breast movement reduction of a large sample of sports bras, and the characteristics which impact sports bra performance. Abbreviations: A-P: anterior-posterior; BMI: body mass index; C7: 7th cervical vertebrae; LNIP: left nipple; M-L: medial-lateral; PX: xiphoid process; ROM: range of motion; S-I: superior-inferior; SD: standard deviation; STN: suprasternal notch; T8: 8th thoracic vertebrae.


Asunto(s)
Vestuario , Carrera , Mama , Femenino , Humanos , Movimiento , Columna Vertebral
11.
Artículo en Inglés | MEDLINE | ID: mdl-32015029

RESUMEN

The aim of this study was to assess the safety of early oral switch (EOS) prior to 14 days for low-risk Staphylococcus aureus bacteremia (LR-SAB), which is the primary treatment strategy used at our institution. The usual recommended therapy is 14 days of intravenous (i.v.) antibiotics. All patients with SAB at our hospital were identified between 1 January 2014 and 31 December 2018. Those meeting low-risk criteria (health care-associated, no evidence of deep infection or demonstrated involvement of prosthetic material, and no further positive blood cultures after 72 h) were included in the study. The primary outcome was occurrence of a SAB-related complication within 90 days. There were 469 SAB episodes during the study period, 100 (21%) of whom met inclusion criteria. EOS was performed in 84 patients. In this group, line infection was the source in 79%, methicillin-susceptible S. aureus caused 95% of SABs and 74% of patients received i.v. flucloxacillin. The median durations of i.v. and oral antibiotics in the EOS group were 5 days (interquartile range [IQR], 4 to 6) and 10 days (IQR, 9 to 14), respectively. A total of 71% of patients received flucloxacillin as their EOS agent. Overall, 86% of oral step-down therapy was with beta-lactams. One patient (1%) undergoing EOS had SAB relapse within 90 days. No deaths attributable to SAB occurred within 90 days. In this low-MRSA-prevalence LR-SAB cohort, EOS was associated with a low incidence of SAB-related complications. This was achieved with oral beta-lactam therapy in most patients. Larger prospective studies are needed to confirm these findings.


Asunto(s)
Bacteriemia , Infecciones Estafilocócicas , Antibacterianos/uso terapéutico , Bacteriemia/tratamiento farmacológico , Humanos , Estudios Prospectivos , Infecciones Estafilocócicas/tratamiento farmacológico , Staphylococcus aureus , beta-Lactamas/uso terapéutico
12.
Aesthet Surg J ; 40(5): NP253-NP262, 2020 04 14.
Artículo en Inglés | MEDLINE | ID: mdl-31504162

RESUMEN

BACKGROUND: Breast implants may increase breast skin tension and interact with surrounding tissues to alter breast position and motion during dynamic activity. Reducing implant mass and changing implant location (submuscular/subglandular) may also affect breast kinematics and the subsequent loads on breast structures. OBJECTIVES: The aim of this pilot study was to describe the kinematics of breasts augmented with reduced-mass implants during standing, walking, and running, compared with natural breasts, and to provide insight into how implant location (submuscular/subglandular) alters breast kinematics. METHODS: Two breast augmentation participants (12-15 months postsurgery: 32AA presurgery, anatomical submuscular 255 cc B-Lite reduced-mass implant; 32A presurgery, anatomical subglandular 285 cc B-Lite reduced-mass implant) and 2 natural-breasted participants of similar breast size and anthropometrics were recruited. Nipple and torso positional data were recorded with electromagnetic sensors during standing, walking, and running. Nipple kinematics relative to the torso were calculated. RESULTS: The B-Lite participants both displayed greater nipple projection and elevation during standing and a 50% reduction in nipple acceleration during walking, when compared with their natural counterparts. During running, the B-Lite subglandular participant displayed decreased nipple kinematics compared with her natural counterpart and lower nipple kinematics compared with the B-Lite submuscular participant during walking and running. CONCLUSIONS: A combination of implant location (subglandular) and reduced mass minimized nipple kinematics during running. Reducing nipple kinematics during dynamic activity may decrease the loading on breast structures, helping to decrease ptosis and increase the longevity of procedure outcomes.


Asunto(s)
Implantación de Mama , Implantes de Mama , Mamoplastia , Fenómenos Biomecánicos , Implantación de Mama/efectos adversos , Femenino , Humanos , Proyectos Piloto
13.
Knee ; 26(3): 595-602, 2019 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-31031126

RESUMEN

BACKGROUND: Patients with a meniscal tear are frequently treated with arthroscopic partial meniscectomy (APM) which may alter the net extension moment across the entire lower limb - known as the total support moment (TSM). PURPOSE: To investigate changes in TSM during walking in patients undergoing APM. METHODS: Three-dimensional motion analysis of walking was performed in individuals with meniscal tear prior to APM and 12 months after. Peak TSM, positive ankle (ASM), knee (KSM), and hip (HSM) moments at the time of peak TSM were calculated together with corresponding angular impulses. RESULTS: Patients (n = 20) were middle aged (45.9 ±â€¯6.3 years) and the majority male (70%). At baseline a lower KSM (mean [95%CI]; 0.59 Nm/BM ·â€¯HT% [-1.93; 3.11], P = 0.048) and a trend towards lower peak TSM (0.46 Nm/BM ·â€¯HT% [-1.82; 2.78], P = 0.099) were observed for the APM leg compared with the contralateral. Pre- versus post-APM change scores indicated a relative decrease in loading of the contralateral leg for peak TSM (-0.49 Nm/BM ·â€¯HT% [-0.96; -0.01], P = 0.047) and a trend towards a relative increase in loading of the APM leg for peak KSM (-0.41 Nm/BM ·â€¯HT% [-0.92; 0.09], P = 0.105). No differences were observed in angular impulse variables. CONCLUSIONS: Prior to APM a strategy to unload the injured knee was manifested by reduced KSM and a tendency to a reduced peak TSM. A more equal distribution of joint moments between injured and contralateral legs was observed 12 months following APM.


Asunto(s)
Extremidad Inferior/fisiopatología , Meniscectomía/métodos , Lesiones de Menisco Tibial/fisiopatología , Lesiones de Menisco Tibial/cirugía , Caminata/fisiología , Adaptación Fisiológica/fisiología , Artroscopía , Estudios de Cohortes , Femenino , Humanos , Estudios Longitudinales , Masculino , Persona de Mediana Edad
14.
Hum Mov Sci ; 59: 30-36, 2018 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-29602049

RESUMEN

It is well understood that stability during ambulation is reliant upon appropriate control of the trunk segment, but research shows that the rhythmicity of this segment is significantly reduced for people with Parkinson's disease (PD). Given the increased risk associated with stair ambulation, this study investigated whether people with PD demonstrate poorer trunk control during stair ambulation compared with age-matched controls. Trunk accelerations were recorded for twelve PD patients and age-matched controls during stair ascent and descent. Accelerations were used to derive measures of harmonic ratios and root mean square (RMS) acceleration to provide insight into the rhythmicity and amplitude of segmental motion. Compared with what is typically seen during level-ground walking, gait rhythmicity during stair negotiation was markedly reduced for older adults and people with PD. Furthermore, both groups exhibited significantly poorer trunk movements during stair descent compared to stair ascent, suggesting that both populations may face a greater risk of falling during this task. As stair negotiation is a common activity of daily life, the increased risk associated with this task should be considered when working with populations that have an increased risk of falling.


Asunto(s)
Enfermedad de Parkinson/fisiopatología , Equilibrio Postural/fisiología , Aceleración , Accidentes por Caídas , Anciano , Fenómenos Biomecánicos/fisiología , Estudios de Casos y Controles , Femenino , Marcha/fisiología , Humanos , Masculino , Persona de Mediana Edad , Movimiento/fisiología , Factores de Riesgo , Torso , Caminata/fisiología
15.
Arch Phys Med Rehabil ; 98(4): 639-648, 2017 04.
Artículo en Inglés | MEDLINE | ID: mdl-27993586

RESUMEN

OBJECTIVE: To evaluate the effect of imposed faster and slower walking speeds on postural stability in people with Parkinson disease (PD). DESIGN: Cross-sectional cohort study. SETTING: General community. PARTICIPANTS: Patients with PD (n=84; 51 with a falls history; 33 without) and age-matched controls (n=82) were invited to participate via neurology clinics and preexisting databases. Of those contacted, 99 did not respond (PD=36; controls=63) and 27 were not interested (PD=18; controls=9). After screening, a further 10 patients were excluded; 5 had deep brain stimulation surgery and 5 could not accommodate to the treadmill. The remaining patients (N=30) completed all assessments and were subdivided into PD fallers (n=10), PD nonfallers (n=10), and age-matched controls (n=10) based on falls history. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Three-dimensional accelerometers assessed head and trunk accelerations and allowed calculation of harmonic ratios and root mean square (RMS) accelerations to assess segment control and movement amplitude. RESULTS: Symptom severity, balance confidence, and medical history were established before participants walked on a treadmill at 70%, 100%, and 130% of their preferred speed. Head and trunk control was lower for PD fallers than PD nonfallers and older adults. Significant interactions indicated head and trunk control increased with speed for PD nonfallers and older adults, but did not improve at faster speeds for PD fallers. Vertical head and trunk accelerations increased with walking speed for PD nonfallers and older adults, while the PD fallers demonstrated greater anteroposterior RMS accelerations compared with both other groups. CONCLUSIONS: The results suggest that improved gait dynamics do not necessarily represent improved walking stability, and this must be respected when rehabilitating gait in patients with PD.


Asunto(s)
Accidentes por Caídas/prevención & control , Trastornos Neurológicos de la Marcha/fisiopatología , Trastornos Neurológicos de la Marcha/rehabilitación , Enfermedad de Parkinson/fisiopatología , Enfermedad de Parkinson/rehabilitación , Equilibrio Postural/fisiología , Velocidad al Caminar/fisiología , Acelerometría , Anciano , Estudios Transversales , Evaluación de la Discapacidad , Femenino , Humanos , Masculino , Calidad de Vida , Resultado del Tratamiento
16.
Gait Posture ; 52: 33-39, 2017 02.
Artículo en Inglés | MEDLINE | ID: mdl-27863279

RESUMEN

BACKGROUND: Stair ambulation is a challenging activity of daily life that requires larger joint moments than walking. Stabilisation of the body and prevention of lower limb collapse during this task depends upon adequately-sized hip, knee and ankle extensor moments. However, people with Parkinson's disease (PD) often present with strength deficits that may impair their capacity to control the lower limbs and ultimately increase their falls risk. OBJECTIVE: To investigate hip, knee and ankle joint moments during stair ascent and descent and determine the contribution of these joints to the body's support in people with PD. METHODS: Twelve PD patients and twelve age-matched controls performed stair ascent and descent trials. Data from an instrumented staircase and a three-dimensional motion analysis system were used to derive sagittal hip, knee and ankle moments. Support moment impulses were calculated by summing all extensor moment impulses and the relative contribution of each joint was calculated. RESULTS: Linear mixed model analyses indicated that PD patients walked slower and had a reduced cadence relative to controls. Although support moment impulses were typically not different between groups during stair ascent or descent, a reduced contribution by the ankle joint required an increased knee joint contribution for the PD patients. CONCLUSIONS: Despite having poorer knee extensor strength, people with PD rely more heavily on these muscles during stair walking. This adaptation could possibly be driven by the somewhat restricted mobility of this joint, which may provide these individuals with an increased sense of stability during these tasks.


Asunto(s)
Adaptación Fisiológica/fisiología , Articulaciones/fisiopatología , Locomoción/fisiología , Extremidad Inferior/fisiopatología , Enfermedad de Parkinson/fisiopatología , Anciano , Fenómenos Biomecánicos/fisiología , Estudios de Casos y Controles , Trastornos Neurológicos de la Marcha/fisiopatología , Humanos , Persona de Mediana Edad
17.
J Biomech ; 49(3): 479-83, 2016 Feb 08.
Artículo en Inglés | MEDLINE | ID: mdl-26783094

RESUMEN

Identification of the impact peak (IP) from the vertical ground reaction force (vGRF) is required to calculate indices of impact loading during running. The IP, however, is not always clearly discernible. Previous researchers have estimated the timing of the IP using surrogate methods, the most common of which is a set time point of 13% stance (TPS). Information contained within the high frequency (HiF) component of the vGRF may also have a utility as a surrogate measure, but the validity of either approach is currently unknown. The purpose of this study is to evaluate the criterion validity for a newly proposed HiF method and the previously used TPS method against a criterion measure for a group of rear-foot striking runners. Fifty participants ran at a standardized speed (3.3 m·s(-1)) on an instrumented treadmill. Five consecutive stance phases were analyzed for the participant's dominant limb. Bland-Altman was used to assess agreement between the criterion method and each surrogate method. Good agreement of the HiF and TPS methods with the criterion method indicate that both methods are likely to be valid surrogate approaches to estimate vGRF impact loading indices. For all impact loading indices, smaller bias and limits of agreement (LOA) were observed with the HiF method when compared to the TPS method. Therefore, it is concluded that the HiF method should be used in preference to the TPS method when it is available.


Asunto(s)
Prueba de Esfuerzo , Carrera/fisiología , Adulto , Fenómenos Biomecánicos , Femenino , Pie , Humanos , Masculino , Fenómenos Mecánicos , Reproducibilidad de los Resultados , Adulto Joven
18.
Clin Biomech (Bristol, Avon) ; 28(7): 825-30, 2013 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-23880449

RESUMEN

BACKGROUND: One of the aims of the sock/shoe unit is to reduce the severity of impact forces on the lower extremity although the injury prevention potential of the sock through the attenuation of impact force has yet to be established. This study aims to determine the effect of athletic socks and a sock/shoe unit on peak impact force, time to peak impact force and loading rate using an impact testing methodology. METHODS: An impact testing system with a gravity driven vertical impact striker (8.5kg) fitted with a load cell (10,000Hz) which was released from 0.05m to impact the specimen on the vertical axis (impact velocity=0.99m·s(-1)) was used throughout the study. FINDINGS: All socks reduced peak impact force by between 6% and 20% when compared to a no sock control condition. Furthermore, large significant correlation coefficients (r=.62 to .72) were observed between thickness and peak impact force, time to peak impact force and loading rate in the sock only condition. INTERPRETATION: Athletic socks demonstrate cushioning properties under impact testing conditions.


Asunto(s)
Vestuario , Pie/fisiología , Soporte de Peso/fisiología , Diseño de Equipo , Humanos , Presión , Zapatos , Deportes
19.
J Appl Biomech ; 2013 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-23549324

RESUMEN

Despite manufacturer claims that athletic socks attenuate force during exercise, no device exists to assess this. Therefore, this study outlines the development of a custom built impact testing device for assessing the cushioning properties of socks. The device utilised a gravity driven impact striker (8.5 kg), released from 0.05 m, which impacted a no sock, sock or a basic shoe/sock condition in the vertical axis. A load cell (10000 Hz) assessed peak impact force, time to peak impact force and loading rate. Reliability was investigated between day, between trial and within trial. Excellent reliability (coefficient of variation < 5% adjusted for 95% confidence limits) was reported for peak impact force in all conditions, with no evidence of systematic bias. Good reliability (coefficient of variation < 10% adjusted for 68% confidence limits) was reported for time to peak impact force and loading rate with some evidence of systematic bias. It was concluded that the custom built impact testing device was reliable and sensitive for the measurement of peak impact force on socks.

20.
J Appl Biomech ; 29(6): 824-31, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-24482259

RESUMEN

Despite manufacturer claims that athletic socks attenuate force during exercise, no device exists to assess this. Therefore, this study outlines the development of a custom-built impact-testing device for assessing the cushioning properties of socks. The device used a gravity-driven impact striker (8.5 kg), released from 0.05 m, which impacted a no-sock, sock or a basic shoe/sock condition in the vertical axis. A load cell (10,000 Hz) assessed peak impact force, time to peak impact force and loading rate. Reliability was investigated between day, between trial and within trial. Excellent reliability (coefficient of variation < 5% adjusted for 95% confidence limits) was reported for peak impact force in all conditions, with no evidence of systematic bias. Good reliability (coefficient of variation < 10% adjusted for 68% confidence limits) was reported for time to peak impact force and loading rate with some evidence of systematic bias. It was concluded that the custom-built impact-testing device was reliable and sensitive for the measurement of peak impact force on socks.


Asunto(s)
Aceleración , Vestuario , Ensayo de Materiales/instrumentación , Estimulación Física/instrumentación , Zapatos , Equipo Deportivo , Módulo de Elasticidad , Diseño de Equipo , Análisis de Falla de Equipo , Dureza , Viscosidad
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