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1.
J Phys Condens Matter ; 21(25): 255802, 2009 Jun 24.
Artículo en Inglés | MEDLINE | ID: mdl-21828442

RESUMEN

We have measured the room temperature response of nanoscale semiconductor Hall crosses to local applied magnetic fields under various local electric gate conditions using scanning probe microscopy. Near-surface quantum wells of AlSb/InAs/AlSb, located just 5 nm from the heterostructure surface, allow very high sensitivity to localized electric and magnetic fields applied near the device surfaces. The Hall crosses have critical dimensions of 400 and 100 nm, while the mean free path of the carriers is about 160 nm; hence the devices nominally span the transition from diffusive to quasi-ballistic transport. With certain small gate voltages (V(g)) the devices of both sizes are strongly responsive to the local magnetic field at the center of the cross, and the results are well described using finite element modeling. At high V(g), the response to local magnetic fields is greatly distorted by strong electric fields applied near the cross corners. However we observe no change in behavior with the size of the device.

2.
Biochem Soc Trans ; 30(2): 73-8, 2002 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-12023828

RESUMEN

Plastic microfluidic array platforms and synergistic multiplexed assay chemistries are under development for a variety of applications, including assays of gene expression, proteomics, genotyping, DNA sequencing and fragment analysis, sample preparation and high-throughput pharmaceutical discovery. The low production costs of plastic substrates makes possible economical single-use device arrays, eliminating cleaning and sample-to-sample carryover contamination. Hundreds of microchannels and reservoirs are readily included on a single microtitre-plate-size substrate, enabling the manufacture of highly parallel fluidic array systems to increase throughput and speed.


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Microquímica/instrumentación , Evaluación Preclínica de Medicamentos/instrumentación , Perfilación de la Expresión Génica/instrumentación , Humanos , Miniaturización , Plásticos , Análisis de Secuencia de ADN/instrumentación
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