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1.
Magn Reson Med ; 70(6): 1739-47, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23440651

RESUMEN

PURPOSE: To determine whether diffusion-weighted imaging (DWI) characteristics could predict the effectiveness of uterine arterial embolization in treatment of fibroids. METHODS: This retrospective study included 17 women (27 fibroids) who underwent uterine arterial embolization for fibroids. MR imaging (1.5 T) was performed before, 1 week and 6 months after uterine arterial embolization. The volume, T2 signal, T1 signal, enhancement after contrast media injection, DWI signal (b = 500 s/mm(2) ) and apparent diffusion coefficient (ADC) were assessed for fibroids. RESULTS: DWI signal or ADC, whether before or 1 week after the procedure, did not show a statistical relationship to success of uterine arterial embolization. On the 1-week follow-up, 22% of fibroids enhanced vs. 85% on baseline, P < 0.0001 and DW signal intensity increased. ADC values in fibroids decreased between baseline and 1-week (1.61 vs. 1.53 × 10(-3) mm(2) /s, P = 0.13). On 6-months, ADC continued to decrease compared with baseline (1.27 × 10(-3) mm(2) /s, P = 0.002), but with a lower signal on DWI. No changes were observed in myometrium ADC at any time point. CONCLUSION: Our study demonstrated that DWI and ADC reflected early and delayed changes in fibroids after embolization; however, we were not able to demonstrate a statistically significant relationship with outcome.


Asunto(s)
Resinas Acrílicas/uso terapéutico , Gelatina/uso terapéutico , Leiomioma/patología , Leiomioma/terapia , Embolización de la Arteria Uterina/métodos , Neoplasias Uterinas/patología , Neoplasias Uterinas/terapia , Adulto , Imagen de Difusión por Resonancia Magnética , Femenino , Hemostáticos/uso terapéutico , Humanos , Persona de Mediana Edad , Pronóstico , Reproducibilidad de los Resultados , Estudios Retrospectivos , Sensibilidad y Especificidad , Resultado del Tratamiento
2.
Int J Gynecol Cancer ; 19(9): 1655-7, 2009 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-19955954

RESUMEN

Vaginal cysts are common lesions that include Gartner cysts, which develop from the wolffian duct remnants in the vaginal wall. Malignant transformation of Gartner cysts is exceedingly rare. Our case was diagnosed upon evaluation of vaginal bleeding in a 67-year-old woman. Histologic examination showed a clear cell carcinoma. Treatment consisted of surgical excision and radiation therapy. Treatment quality, stage, and pelvic node status are the main prognostic factors. Regular long-term follow-up is crucial.


Asunto(s)
Transformación Celular Neoplásica , Quistes/patología , Enfermedades Vaginales/patología , Conductos Mesonéfricos/patología , Adenocarcinoma/diagnóstico , Adenocarcinoma/patología , Anciano , Transformación Celular Neoplásica/patología , Progresión de la Enfermedad , Femenino , Humanos , Neoplasias Urogenitales/diagnóstico , Neoplasias Urogenitales/patología
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