1.
Org Biomol Chem
; 10(39): 7872-4, 2012 Oct 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-22961337
RESUMEN
Two fluorescent lysine amide analogs, in which the carboxyl end of lysine was covalently attached to dansyl or NBD groups through an ethylene glycol-based linker, were rationally designed and synthesized. Both probes showed high binding affinity to the lysine riboswitch in vitro and their fluorescence intensities decreased by riboswitch binding.