Asunto(s)
Enfermedades Transmitidas por los Alimentos/epidemiología , Carne/parasitología , Sus scrofa/parasitología , Triquinelosis/epidemiología , Animales , Brotes de Enfermedades/prevención & control , Manipulación de Alimentos/métodos , Enfermedades Transmitidas por los Alimentos/parasitología , Enfermedades Transmitidas por los Alimentos/prevención & control , Francia/epidemiología , Humanos , Trichinella/aislamiento & purificación , Triquinelosis/diagnóstico , Triquinelosis/prevención & controlRESUMEN
We report a single case of trichinellosis contracted in Algeria (Batna region), in a practising Moslim. Shortly after returning to France in November 2004, the patient developed the typical clinical and biological signs of the disease. Although the patient claimed having only eaten mutton, an unusual host for Trichinella, a meticulous investigation revealed that he also had eaten a grilled leg of jackal (Canis aureus). One of the four Trichinella larvae detected in a muscular biopsy enabled us to identify the parasite as Trichinella britovi by a multiplex PCR analysis. This is the first identification of the etiological agent of sylvatic trichinellosis occurring in North Africa and the first case of symptomatic trichinellosis due to jackal meat consumption in Africa.
Asunto(s)
Chacales , Carne/parasitología , Trichinella , Triquinelosis/diagnóstico , Anciano , Argelia , Animales , Biopsia , Humanos , Masculino , Músculo Esquelético/parasitología , Reacción en Cadena de la Polimerasa , Trichinella/genética , Trichinella/aislamiento & purificación , Triquinelosis/etiologíaRESUMEN
A study of RBC membrane functions was performed in four patients suffering from familial hypokalemic periodic paralysis who had permanent muscular weakness. Electrophoretograms of membrane proteins, cell deformability, calcium-promoted potassium efflux, calcium-ATPase activity, and endogeneous phosphorylation of membrane proteins were all within the normal range. These results are compared with similar studies performed in myotonic and Duchenne-type dystrophies, in which abnormalities in the RBC membrane have been described. The results do not support the theory of RBC involvement in hypokalemic periodic paralysis. However, this does not imply that the muscle cell membrane is not involved in the underlying pathological processes in this disorder.