1.
An Esp Pediatr
; 47(3): 334, 1997 Sep.
Artículo
en Español
| MEDLINE
| ID: mdl-9499295
2.
An Esp Pediatr
; 35(1): 71-2, 1991 Jul.
Artículo
en Español
| MEDLINE
| ID: mdl-1772179
3.
An Esp Pediatr
; 33(1): 58-60, 1990 Jul.
Artículo
en Español
| MEDLINE
| ID: mdl-2252289
RESUMEN
Homozygous familiar hypercholesterolemia (FH) is a serious inherited disease caused by a genetic defect in the cell surface receptor that controls the degradation of low density lipoprotein (LDL). These patients often have myocardial infarction in their teens or early adulthood and are usually unresponsive to drugs. Recently it has been reported promising results using combined drugs regimens in patients with residual receptor activity. We report a new additional patient with receptor-defective homozygous FH treated with a combination of lovastatin and cholestyramine. The cholesterol levels were reduced in a 67% and there were adverse events related to treatment during a 7 month period of follow-up.
Asunto(s)
Resina de Colestiramina/uso terapéutico , Hiperlipoproteinemia Tipo II/genética , Lovastatina/uso terapéutico , Preescolar , Quimioterapia Combinada , Homocigoto , Humanos , Hiperlipoproteinemia Tipo II/tratamiento farmacológico , Masculino
4.
An Esp Pediatr
; 29(2): 181-2, 1988 Aug.
Artículo
en Español
| MEDLINE
| ID: mdl-3056153
5.
An Esp Pediatr
; 25 Suppl 26: 7-11, 1986 Oct.
Artículo
en Español
| MEDLINE
| ID: mdl-3826935