Generating Demand for Alternative Protein in Low- and Middle- Income Countries: Opportunities and Experiences from Nutritious and Sustainable Market Solutions.

Protein consumption and the demand for high-value nutritional products is growing rapidly in emerging markets. The projected growth of the alternative protein industry may position it well to meet this demand while addressing environmental sustainability and ethical standards. However, adoption of alternative protein products over traditional animal-sourced proteins is not always a clear choice, with factors such as consumer preferences and habitual behaviors influencing consumer decisions. Insights and considerations associated with generating demand for alternative protein products in low- and middle-income countries (LMIC) were identified through 3 case studies: the OBAASIMA Project in Ghana, the Egg Initiative in Ethiopia, and the World Food Programme Farming Coalition project in Armenia. Key findings emphasize the importance of local sourcing, positive messaging, and integration within existing diets and behaviors. Therefore, these factors will be essential for the adoption of novel alternative protein products in LMIC.

Ten considerations for effectively managing the COVID-19 transition.

Governments around the world have implemented measures to manage the transmission of coronavirus disease 2019 (COVID-19). While the majority of these measures are proving effective, they have a high social and economic cost, and response strategies are being adjusted. The World Health Organization (WHO) recommends that communities should have a voice, be informed and engaged, and participate in this transition phase. We propose ten considerations to support this principle: (1) implement a phased approach to a 'new normal'; (2) balance individual rights with the social good; (3) prioritise people at highest risk of negative consequences; (4) provide special support for healthcare workers and care staff; (5) build, strengthen and maintain trust; (6) enlist existing social norms and foster healthy new norms; (7) increase resilience and self-efficacy; (8) use clear and positive language; (9) anticipate and manage misinformation; and (10) engage with media outlets. The transition phase should also be informed by real-time data according to which governmental responses should be updated.

Determinación de la ganancia de peso, claidad proteica y digestibilidad de ocho dietas a base de dos leguminosas, maní (Arachis hypogaea L. ) y ajonjolí (Sesamum indicum L. ) en ratas Wistar / Determination of weight gain, protein quality and digestibility of eight diets based on two legumes, peanut (Arachis hypogaea L. ) and sesame (Sesamum indicum L. ) in Wistar rats

El maní y ajonjolí, son dos fuentes importantes de macronutrientes y micronutrientes. El objetivo del estudio fue evaluar la ganancia de peso, calidad proteica y digestibilidad en ocho dietas compuestas a base de dos leguminosas, en ratas Wistar durante cuatro semanas. Las dietas se clasificaron en dieta control; dieta A (leche descremada), dieta B (libre de nitrógeno), dietas C, D, E, F (conformadas por 100%, 75%, 50%, 25% de maní complementadas con leche descremada), y dietas G, H, I, J (conformadas por 100%, 75%, 50%, 25% de ajonjolí, complementadas con leche descremada). Se encontraron diferencias significativas en la ganancia de peso en relación a la dieta control, principalmente en los grupos de ratas que consumieron la dieta D, maní 75% con un valor medio después de las cuatros semanas de 226.00 g (SD=55.29)(p<.05), dieta H, ajonjolí 75%, con un valor medio de 218.16 g (SD=56.28)(p<.05), y dieta I, ajonjolí 50%, con un valor medio de 216.83 g (SD=45.86)(p<.05). Las dietas formuladas con leche y leguminosas fueron de alta digestibilidad (96% - 100%), con un índice de eficiencia proteica de 2.73, muy similar al encontrado en la dieta control. Estas formulaciones basadas en leguminosas podrían tener potencial uso en la nutrición humana.

Peanuts and sesame are two important sources of macronutrients and micronutrients. The objectives of this study were to evaluate the weight gain, protein quality and digestibility of eight legume-based diets in Wistar rats during a period of four weeks. The diets were classified as: control diet, diet A (skim milk), diet B (nitrogen free), diets C, D, E, F (with peanuts in a proportion that varied from 100%, 75%, 50% to 25%, mixed with skim milk), diets G, H, I, J (with sesame in a proportion that varied from 100%, 75, 50% to 25%, mixed with skim milk). The study showed significant differences in weight gain when comparing with the control diet, particularly with diet D (75% peanut) with 226 g (SD=55.29) (p<0.05), diet H (75% sesame) with 218.16 g (SD=56.28) (p<0.05), and diet I (50% sesame) with 216.83 g (SD=45.86) (p<0.05). The study showed that the diets with skim milk and legumes were highly digestible (96% - 100%), with protein efficiency ratio (PER) of 2.73, very similar to the control diet. These formulations are promising and have potential implications for human nutrition.

Aceptabilidad y uso en el hogar de un alimento complementario listo para consumir en el área rural de Guatemala / Acceptability and use at home of ready to use complementary food in families of rural Guatemala

Con el objetivo de apoyar el plan del Gobierno de Guatemala para reducir las tasas de desnutrición crónica, el Instituto de Nutrición de Centro América y Panamá (INCAP) desarrolló un Alimento Complementario Listo para Consumir (ACLC), el cual está hecho con una base de pasta de maní, leche y micronutrientes para aportar un rango entre el 50 y el 60% de las recomendaciones diarias en micronutrientes, según el INCAP para niños de 6-24 meses de edad. El objetivo de este estudio fue evaluar la aceptabilidad y uso del ACLC en niños de 6 a 24 meses de edad (estratificados en grupos de 6-12, 13-18 y >18 meses de edad) y sus madres, en una comunidad rural maya q'eqchi' con alta vulnerabilidad a la desnutrición crónica infantil, ubicada al norte de Guatemala. 46 fueron evaluadas por medio de pruebas sensoriales y grupos focales. 43 niños fueron evaluados a través del consumo del alimento, durante un período de ocho semanas. La aceptabilidad global del alimento por parte de la madre ("le gusta") fue de un 89.8%. La aceptabilidad en 43 niños, evaluada en la séptima semana de intervención (S7), mostró una mediana de consumo de 31.9 + 1.7 g por día (93.8% del producto disponible, cuyo peso promedio fue de 34.0 g por paquete), lo cual fue comparable en los tres grupos etarios estudiados. En conclusión, el ACLC tuvo una aceptabilidad y uso adecuados en la población estudiada, lo que respalda continuar el desarrollo y uso de esta formulación, como una alternativa en la implementación de programas preventivos de la desnutrición crónica infantil en Guatemala

To support national government plan to reduce infant chronic malnutrition rates in Guatemala, (Spanish acronym of: Institute of Nutrition of Central America and Panama) INCAP developed a formula called Complementary Food Ready for Consumption (Spanish acronym: ACLC). It is made of peanut paste, milk and micronutrients. This formula covers around 50 to 60% of daily micronutrients recommendations (INCAP 2012) for 6-24 months' infants. The objective of this study was to assess the acceptability and use of ACLC (Maní+) in mothers and infants between 6-24 months (stratified in groups of 6-12, 13-18 y >18 months of age), in a Q'eqchi´ Mayan rural community located in the north of Guatemala, which has a high chronic child malnutrition rate. Forty six mothers were evaluated through sensory tests and focus groups. Furthermore, forty three infants were evaluated through the formula consumption during a period of eight weeks. Food Global acceptability from mothers (they like it) was 89.8 %. Acceptability in forty-three infants was assessed after seven weeks of intervention. It showed a food consumption of 31.9 +1.7 g per day (93.8% of available product, which average weight was 34.0 g per sachet), which was compared among three age range. Therefore this study showed that ACLC had a good acceptability and appropriate use in the study population. This study bears to continue the use and development of this formula, as an option for preventive programs implementation of infant chronic malnutrition in Guatemala.

Predictive validity of the attitudes toward medical help-seeking scale.

OBJECTIVE: This study examines the predictive validity of the action/intention subscale of the attitudes toward seeking medical help scale in a college sample. PARTICIPANTS: Participants were 51 female undergraduates recruited from psychology classes. Data were collected at two time points between January and April, 2011. METHODS: Students completed the attitudes subscale and a measure of medical contacts twice, over a two month interval. RESULTS: Internal consistency and test-retest reliability of the measure were supported. Correlations between time one attitudes and medical contacts/intentions at time two provide evidence for predictive validity of the measure. CONCLUSION: This relatively brief, psychometrically sound measure of attitudes toward medical help seeking can be used to identify individuals who may be reluctant to seek health care and to assess the effectiveness of health education programs.

Multidimensional poverty in rural Mozambique: a new metric for evaluating public health interventions.

BACKGROUND: Poverty is a multidimensional phenomenon and unidimensional measurements have proven inadequate to the challenge of assessing its dynamics. Dynamics between poverty and public health intervention is among the most difficult yet important problems faced in development. We sought to demonstrate how multidimensional poverty measures can be utilized in the evaluation of public health interventions; and to create geospatial maps of poverty deprivation to aid implementers in prioritizing program planning. METHODS: Survey teams interviewed a representative sample of 3,749 female heads of household in 259 enumeration areas across Zambézia in August-September 2010. We estimated a multidimensional poverty index, which can be disaggregated into context-specific indicators. We produced an MPI comprised of 3 dimensions and 11 weighted indicators selected from the survey. Households were identified as "poor" if were deprived in >33% of indicators. Our MPI is an adjusted headcount, calculated by multiplying the proportion identified as poor (headcount) and the poverty gap (average deprivation). Geospatial visualizations of poverty deprivation were created as a contextual baseline for future evaluation. RESULTS: In our rural (96%) and urban (4%) interviewees, the 33% deprivation cut-off suggested 58.2% of households were poor (29.3% of urban vs. 59.5% of rural). Among the poor, households experienced an average deprivation of 46%; thus the MPI/adjusted headcount is 0.27 ( = 0.58×0.46). Of households where a local language was the primary language, 58.6% were considered poor versus Portuguese-speaking households where 73.5% were considered non-poor. Living standard is the dominant deprivation, followed by health, and then education. CONCLUSIONS: Multidimensional poverty measurement can be integrated into program design for public health interventions, and geospatial visualization helps examine the impact of intervention deployment within the context of distinct poverty conditions. Both permit program implementers to focus resources and critically explore linkages between poverty and its social determinants, thus deriving useful findings for evidence-based planning.

Frustrated Freedom: The Effects of Agency and Wealth on Wellbeing in Rural Mozambique.

In Sen's capability view of poverty, wellbeing is threatened by both deficits of wealth and deficits of individual agency. Sen further predicts that "unfreedom," or low levels of agency will suppress the wellbeing effects of higher levels of wealth. The current paper extends Sen's view to include a condition, labeled "frustrated freedom," in which relatively higher levels of agency can heighten the poverty effects of relatively low levels of material wealth. Applying data from a large scale population study of female heads of household in rural Mozambique, the paper empirically tests Sen's view and the proposed extension. As predicted, agency is found to moderate the relationship between agency, wealth, and wellbeing, uncovering evidence of both unfreedom and frustrated freedom in the population. Further research into the complex dynamics of wellbeing and poverty are called for by the authors.

Safety effects of reducing freeway illumination for energy conservation.

The addition of illumination where none was present is generally believed to have a positive effect on motor vehicle safety; reducing the frequency, as well as the severity of crashes. The operational cost of illumination, however, can make it a candidate for conservation during periods of high energy costs. In response to a forecasted energy shortage, the Oregon Department of Transportation selectively reduced illumination on interstate highways as part of an energy-saving effort. The reductions occurred at 44 interchanges and along 5.5 miles of interstate highway. This paper presents the results of a crash-based analysis of the changes in safety performance using an empirical-Bayes observational methodology. The study found an increase in reported crashes where the lineal lighting was reduced both in total crashes (28.95%, P=0.05) and injury night crashes (39.21%, P=0.07). Where full interchange lighting was reduced to partial lighting, a 2.46% increase (P=0.007) in total night crashes was observed. Injury night crashes, however, decreased by 12.16% (P<0.001) though day injury crashes also decreased at these locations. Unexpectedly, for interchanges where illumination was reduced from partial plus to partial, a 35.24% decrease (P<0.001) in total crashes and 39.98 (P<0.001) decrease in injury night crashes was found, though again, day crashes also decreased.

Coffee and cigarette consumption and perceived effects in recovering alcoholics participating in Alcoholics Anonymous in Nashville, Tennessee, USA.

BACKGROUND: Alcoholics Anonymous (AA) members represent an important and relatively understudied population for improving our understanding of alcohol dependence recovery as over 1 million Americans participate in the program. Further insight into coffee and cigarette use by these individuals is necessary given AA members' apparent widespread consumption and the recognized health consequences and psychopharmacological actions of these substances. METHODS: Volunteers were sought from all open-AA meetings in Nashville, TN during the summer of 2007 to complete a questionnaire (n = 289, completion rate = 94.1%) including timeline followback for coffee, cigarette, and alcohol consumption; the Alcoholics Anonymous Affiliation Scale; coffee consumption and effects questions; the Fagerstrom Test for Nicotine Dependence (FTND); and the Smoking Effects Questionnaire. RESULTS: Mean (+/-SD) age of onset of alcohol consumption was 15.4 +/- 4.2 years and mean lifetime alcohol consumption was 1026.0 +/- 772.8 kg ethanol. Median declared alcohol abstinence was 2.1 years (range: 0 days to 41.1 years) and median lifetime AA attendance was 1000.0 meetings (range: 4 to 44,209 meetings); average AA affiliation score was 7.6 +/- 1.5. Most (88.5%) individuals consumed coffee and approximately 33% of coffee consumers drank more than 4 cups per day (M = 3.9 +/- 3.9). The most common self-reported reasons for coffee consumption and coffee-associated behavioral changes were related to stimulatory effects. More than half (56.9%) of individuals in AA smoked cigarettes. Of those who smoked, 78.7% consumed at least half a pack of cigarettes per day (M = 21.8 +/- 12.3). Smokers' FTND scores were 5.8 +/- 2.4; over 60% of smokers were highly or very highly dependent. Reduced negative affect was the most important subjective effect of smoking. CONCLUSIONS: A greater proportion of AA participants drink coffee and smoke cigarettes in larger per capita amounts than observed in general U.S. populations. The effects of these products as described by AA participants suggest significant stimulation and negative affect reduction. Fundamental knowledge of the quantitative and qualitative aspects of coffee and cigarette consumption among AA members will enable future research to discern their impact on alcohol abstinence and recovery.

Urban ethnic minority women's attendance at health clinic vs. church based exercise programs.

Older, sedentary, urban-living, ethnic minority women are at high risk for preventable disease, but it is difficult to engage this population in health promotion efforts. This study tested two methods of engaging Hispanic and African American women, who were at high risk for cardiovascular disease, in a 10-week aerobic fitness program. The program was offered to 76 participants, in either a women's health clinic or a church. Attendance was the primary dependent variable and was recorded at each exercise session. Other variables, including the Baecke Questionnaire of Habitual Physical Activity, Fat Frequency Questionnaire, Self-Efficacy for Exercise Behaviors Scale, Social Support and Exercise Survey, and Psychological General Well-Being Schedule, were measured prior to the intervention, at the end of the 10-week program, and at 3-month follow-up. Age predicted attendance, independently of site. Women in the highest age quartile (50 - 70 years) attended more than twice as many exercise sessions compared to women in the lowest age quartile (17 - 27 years). The relationship between older age and attendance was particularly strong for Hispanic women. Church parishioners were primarily women over the age of 40, making it impossible to disentangle the relative effect of locale. These findings are relevant for clinicians who design exercise programs targeting older, ethnic, minority women. Administrators who design exercise programs for urban-living women should consider age of the target population when selecting the most conducive setting.

Efficacy and cost-effectiveness of a clinic-based counseling intervention tested in an ethnically diverse sample of pregnant smokers.

OBJECTIVE: Rates of cigarette smoking are higher among women who receive obstetric care through publicly funded prenatal clinics. This study compared smoking outcomes for pregnant women (n=105) who were randomized to receive either usual care (standard cessation advice from the health care provider) or an intervention conducted in the prenatal clinic consisting of 1.5 h of counseling plus telephone follow-up delivered by a masters prepared mental health counselor. METHODS: Subjects were 105 low income, predominantly Hispanic, pregnant patients in an urban prenatal clinic. Smoking outcomes were assessed at end of pregnancy and 6 months post-partum. RESULTS: At follow-up, 28.3% and 9.4% of participants in the experimental intervention and 9.6% and 3.8% of patients in usual care were abstinent at end of pregnancy (p=.015) and 6 months post-partum, respectively (p=.251). Cost of the intervention was $56 per patient and cost to produce a non-smoker at end of pregnancy was $299. CONCLUSIONS: This model for intervention was cost-effective and was associated with significantly lower smoking rates at end of pregnancy. PRACTICAL IMPLICATIONS: If these findings are replicated, prenatal clinics could offer the option for intensive smoking cessation treatment by training mental health counselors to deliver one extended smoking cessation counseling session.

Spontaneous smoking cessation during pregnancy among ethnic minority women: a preliminary investigation.

This study examined the postpartum relapse rates and characteristics of pregnant women who stopped smoking without professional intervention. Baseline characteristics of women who spontaneously quit were compared to women who continued to smoke. Women who spontaneously quit were also randomized to a psychotherapy relapse prevention treatment, or to usual care. The sample was ethnically diverse, containing 141 low-income women who were predominantly Hispanic, 23% (n=33) of whom spontaneously quit smoking. The variables that significantly differentiated between "spontaneous quitters" and ongoing smokers were entered into a regression analysis, which revealed that higher self-confidence, smoking fewer cigarettes per day, and younger age accounted for 25% of the variance in spontaneous cessation. Adding the psychotherapy intervention conferred no additional protection against relapse in this subgroup of spontaneous quitters. The six-month abstinence rate of 36% is similar to that found in Caucasian and higher-income populations. These results extend research with pregnant smokers to a new population and may have implications for healthcare providers and policy makers.

Ethnic variation in socioenvironmental factors that influence adolescent smoking.

PURPOSE: To compare black, Hispanic and white adolescent smokers on socioenvironmental factors associated with smoking. METHODS: The study uses a cross-sectional design. A needs assessment of 1305 current, former and never adolescent smokers from four ethnically and geographically diverse sites in the United States was conducted in 1999. Two sites were selected because they represented urban cities in the Northeast and Midwest with a high proportion of black and Hispanic residents. Two additional sites were selected to recruit rural and suburban adolescents. From this larger sample, 181 subjects from three focal ethnic groups (white n = 138; black n = 24; Hispanic n = 19) who had smoked at least 100 cigarettes in their lifetime and were current smokers (smoked in the past 30 days) were included. The three ethnic groups were compared on the following variables of interest: peer and family influences on smoking, situational factors associated with smoking, places that were likely sites for smoking and perceptions of friends and family as potential support persons for quitting smoking. All data were analyzed with Chi-square analysis. RESULTS: Almost all (96%) of the black adolescents lived with another smoker compared to 68% of Hispanic and 60% of whites (p = .004). Black teens were more likely to smoke with family members (50%) than Hispanics (5%) or whites (25%) (p = .003). In addition, 50% of black teens compared to 5% of Hispanics and 12% of white teens, reported smoking to fit in (p < .0001). Black teens in this study emphasized the familial and social pressures of smoking. Higher rates of acceptance of smoking by family members, role modeling by household members, more prevalent beliefs that smoking is a way to achieve belonging, and lack of perceived support for quitting by friends appear to influence cigarette smoking more for black than white or Hispanic youth. CONCLUSIONS: These preliminary results indicate that familial and household norms play a critical role in influencing cigarette smoking among black teens.

Continuous intrathecal baclofen infusion by a programmable pump in 131 consecutive patients with severe spasticity of spinal origin.

We began this study to determine the efficacy and safety of intrathecal baclofen (ITB) delivered by a programmable pump for the treatment of severe spasticity of spinal cord origin. One hundred fifty two patients with severe spasticity of spinal origin, refractory to oral baclofen, or who experienced intolerable side-effects were given a test dose of ITB. Only those who had a satisfactory response were considered to be appropriate for pump implantation. All but one of the 152 patients had a satisfactory response, and the pump was implanted in 131 patients. Pre- and postoperative spasticity scores were compared and analyzed. The mean Ashworth score for rigidity decreased from 4.2 preoperatively to 1.3 (p < 0.0005) on ITB. The spasm score decreased from a mean of 3.4 to 0.6 (p < 0.0005). Reduction of spasticity resulted in improved levels of physical activity, decreased pain, and augmentation of sleep. Drug-related complications included constipation, muscular hypotonia, urinary retention, erectile dysfunction, nausea, dizziness, drowsiness, hypotension and bradycardia as well as tolerance to baclofen. Some patients experienced post-spinal puncture headaches. Catheter-related problems included occlusions, breaks, punctures, and dislodgments. Superficial pump pocket infection, pocket erosion, cerebrospinal fluid (CSF) leak, post-spinal puncture headache, and meningitis were some of the procedure-related complications. Two pumps flipped and another pump valve was stuck. We conclude that long-term intrathecal baclofen by an implanted programmable pump is a safe and effective method of treating severe intractable spinal spasticity.

Continuous intrathecal baclofen infusion delivered by a programmable pump for the treatment of severe spasticity following traumatic brain injury.

The aim of this study was to determine the efficacy and safety of intrathecal baclofen (ITB) delivered by a programmable pump for the chronic treatment of severe spasticity due to traumatic brain injury (TBI). Eight patients with severe spasticity following TBI, refractory to oral baclofen or who experienced intolerable side effects, were screened. The first five patients were enrolled in a research protocol that was approved by the Institutional Review Board for Human Research at Boston University Medical Center. The other three patients were evaluated after the FDA approved the therapy for spasticity of cerebral origin. Results showed that the mean Ashworth score for rigidity in the legs decreased from 4.4 preoperatively to 1.3 (p < 0.05) on ITB. In the arms, the Ashworth score decreased from 2.7 to 1.5 (p < 0.05). Reduction of spasticity resulted in improved levels of physical activity and locomotion and ease of care. Complications consisted of muscular hypotonia, areflexic bladder and urinary retention, erythema, and breakdown of the skin over the pump. Our results suggest that long-term intrathecal baclofen by an implanted programmable pump is a safe and effective method of treating severe intractable spasticity arising from traumatic brain injury.

Student nurses view an abortion client: attitude and context effects.

PIP: Two studies of attitudes toward abortion were conducted 1) to determine the effects of religion and personal conviction on attitude, and 2) to determine the amount of stigma attached to an abortion patient. The total sample included 198 student nurses at 3 training hospitals in Connecticut. 191 were women; 62% were Roman Catholic. A "Conflict Situations and Decision-Making" booklet was administered. The booklet told the story of a married women who wants an abortion which is opposed by her husband. The number of children she had and the reasons for the abortion varied in 9 combinations. The booklet was followed by a population and birth planning questionnaire which further developed attitudinal measurement. The reason for wanting the abortion and the number of children most strongly affected evaluation of wife's decision. Frequency of church attendance corresponded negatively to support for wife and was more pronounced for Catholics. The second study utilized a "Personality Impressions" booklet containing several case profiles. 156 student nurses responded attitudinally to an abortion case, a mental patient, and a surgery patient. Personality ratings were more favorable for psychiatric or surgery patient than for an abortion.^ieng