1.
Org Biomol Chem
; 21(7): 1463-1467, 2023 Feb 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-36655521
RESUMEN
An efficient approach to the photoredox-catalysed hydroaminoalkylation between on-DNA secondary N-substituted (hetero)arylamines and vinylarenes has been developed and explored. The methodology was examined with a broad scope of vinylarenes and secondary arylamines to establish a preferred building block profile for the process. Compatible substrates furnished the desired derivitised amine products in modest to excellent conversions and with minimal or no detectable by-products.