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1.
J Low Genit Tract Dis ; 27(4): 351-355, 2023 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-37589319

RESUMEN

METHODS: The authors conducted a survey for practicing gynecologists recruited through academic institutions, professional societies, and professional groups on social media resulting in 196 respondents. The survey, fielded between January and June 2022, included questions on knowledge, attitudes, training, and practices regarding anal cancer prevention (ACP). Descriptive statistics and χ 2 analysis were completed. RESULTS: In terms of knowledge regarding ACP, over 80% of respondents identified certain clinical indications for anal cancer screening. However, only 36% respondents selected the 3 correct ACP screening tools. Twenty-seven (13.9%) respondents reported receiving training on ACP in medical school, whereas 50 (25.9%) reported receiving training during residency. Only 21% of respondents reported that they perform anal cytology, and 32% reported that they perform digital anal rectal examinations. One hundred thirty-six respondents (75.56%) affirmed that they needed additional training on ACP to be able to provide this service to their patients, and 95 (53.1%) stated they were extremely likely to participate in ACP training if given the opportunity. CONCLUSION: Although a limited proportion of practicing gynecologists are trained in ACP, there is willingness to participate in training if it were made available and to incorporate ACP into their practices.


Asunto(s)
Neoplasias del Ano , Internado y Residencia , Medios de Comunicación Sociales , Humanos , Detección Precoz del Cáncer , Ginecólogos , Neoplasias del Ano/diagnóstico , Neoplasias del Ano/prevención & control
2.
J Pediatr Intensive Care ; 12(1): 44-54, 2023 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-36742253

RESUMEN

Very little data is available to understand the drivers of burnout amongst health care workers in the pediatric intensive care unit. This is a survey-based, cross-sectional, point-prevalence analysis within a single children's health system with two free-standing hospitals (one academic and one private) to characterize the relationship of demographics, organizational support, organizational culture, relationship quality, conflict and work schedules with self-reported burnout. Burnout was identified in 152 (39.7%) of the 383 (38.7%) respondents. No significant relationship was identified between burnout and demographic factors or work schedule. A more constructive culture (odds ratio [OR], 0.84; 95% confidence interval [CI], 0.77-0.90; p < 0.001), more organizational support (OR, 0.94; 95% CI, 0.92-0.96; p <0 0.001), and better staff relationships (OR, 0.54, 95% CI, 0.43-0.69; p < 0.001) reduced odds of burnout. More conflict increased odds (OR, 1.25; 95% CI, 1.12-1.39; p < 0.001). Less organizational support ( Z ß = 0.425) was the most important factor associated with burnout overall. A work environment where staff experience defensive cultures, poor relationships, more frequent conflict, and feel unsupported by the organization is associated with significantly higher odds of burnout in pediatric critical care. The effect of targeted interventions to promote constructive cultures, collegiality, and organizational support on burnout in pediatric intensive care should be studied.

3.
Psychol Serv ; 20(3): 647-656, 2023 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-34793190

RESUMEN

Although partnerships between community-based mental health (MH) organizations and school systems to deliver MH services on school grounds (i.e., expanded school mental health, ESMH services) are growing, qualitative research is needed about stakeholders' perspectives on ESMH services. This study collected qualitative data from caregivers, MH providers, and MH administrators recruited from three MH organizations to understand their perspectives regarding potential advantages and challenges associated with ESMH services. The three MH organizations were located in three regions of Georgia and the majority of youth served by the organizations were enrolled in Medicaid. We conducted four focus groups with 33 caregivers and 13 semistructured interviews with MH administrators and providers, and we implemented a thematic content analysis. Caregivers, providers, and MH administrators described how ESMH services could improve MH services by (a) facilitating appointment attendance through the reduction of logistical barriers to care (including geographic barriers, missed class time, and missed work time) and (b) enhancing communication between providers and teachers. However, some participants also described logistical issues with ESMH services including school space constraints and challenges scheduling appointments. In addition, some caregivers expressed concerns about peer stigma if MH services are delivered at school (vs. the clinic). Providers and MH administrators discussed problems with low caregiver engagement and challenges collaborating with school personnel that stem from lack of understanding of MH problems and treatment. Although ESMH services can improve MH treatment among low-income youth, MH providers and MH administrators may consider collaborating with school personnel to proactively develop strategies to address challenges to its success. (PsycInfo Database Record (c) 2023 APA, all rights reserved).


Asunto(s)
Servicios de Salud Mental , Servicios de Salud Mental Escolar , Humanos , Adolescente , Medicaid , Cuidadores/psicología , Investigación Cualitativa
4.
Pediatr Cardiol ; 41(6): 1220-1230, 2020 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-32500288

RESUMEN

With increasing survival trends for children and adolescents with congenital heart defects (CHD), there is a growing need to focus on transition from pediatric to adult specialty cardiac care. To better understand parental perspectives on the transition process, a survey was distributed to 451 parents of adolescents with CHD who had recent contact with the healthcare system in Georgia (GA) and New York (NY). Among respondents, 90.7% reported excellent, very good or good health-related quality of life (HRQoL) for their adolescent. While the majority of parents (77.8%) had been told by a provider about their adolescent's need to transition to adult specialty cardiac care, most reported concerns about transitioning to adult care. Parents were most commonly concerned with replacing the strong relationship with pediatric providers (60.7%), locating an appropriate adult provider (48.7%), and accessing adult health insurance coverage (43.6%). These findings may offer insights into transition planning for adolescents with CHD.


Asunto(s)
Actitud Frente a la Salud , Cardiopatías Congénitas/terapia , Padres/psicología , Transición a la Atención de Adultos , Adolescente , Adulto , Niño , Femenino , Georgia , Humanos , Seguro de Salud , Masculino , New York , Calidad de Vida , Encuestas y Cuestionarios
5.
J Technol Behav Sci ; 4(1): 6-16, 2019 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-31106258

RESUMEN

OBJECTIVE: To examine stakeholder perspectives regarding: (1) whether mobile health (MHealth) tools can improve the mental health (MH) treatment process for low-income youth with ADHD in safety net settings; and (2) what functions would be helpful to improve the treatment process. METHODS: This study analyzed qualitative data from a larger project that collected information from key stakeholders at four safety-net clinics across Georgia. We conducted five focus groups with caregivers who had a Medicaid-insured child receiving treatment for ADHD, and 17 semi-structured interviews with clinic administrators and providers. Stakeholders shared their perspectives on strategies to improve the MH treatment process, including the use of mHealth tools. Caregivers also completed a brief survey about technology use. We present findings from a thematic analysis of the qualitative data and descriptive findings from the survey. RESULTS: Participants in each group of stakeholders expressed interest in mHealth tools that would: (1) deliver reminders for caregivers (including appointment and medication refill reminders); (2) help caregivers obtain information about ADHD symptoms and treatment options; (3) help caregivers track information about their child's symptoms and treatment progress; and (4) facilitate communication between caregivers and providers. While more than three-fourths of caregivers had a smartphone, providers and administrators expressed concern that access to mHealth technologies may be inconsistent if low-income families are unable to pay cellular phone bills. CONCLUSIONS: Caregivers, clinic administrators, and providers were supportive of enhanced mHealth technologies to improve MH care for this population.

6.
Adm Policy Ment Health ; 46(5): 580-595, 2019 09.
Artículo en Inglés | MEDLINE | ID: mdl-30993569

RESUMEN

This qualitative study describes how Medicaid policies create challenges for the delivery and receipt of mental health treatment for low-income youth in Georgia. We conducted focus groups with caregivers of Medicaid-enrolled children with ADHD and semi-structured interviews with providers and administrators at four safety net clinics that provided mental health care to these youth. Stakeholders reported that prior authorization policies for psychosocial services, restrictiveness of preferred drug lists, and changes in preferred drug lists in Medicaid plans created barriers to treatment continuity and quality for youth with ADHD and led to more administrative burden for safety-net clinics serving these youth.


Asunto(s)
Trastorno por Déficit de Atención con Hiperactividad/tratamiento farmacológico , Actitud del Personal de Salud , Cuidadores/psicología , Formularios Farmacéuticos como Asunto/normas , Medicaid/organización & administración , Autorización Previa/organización & administración , Adolescente , Adulto , Niño , Continuidad de la Atención al Paciente/organización & administración , Femenino , Georgia , Accesibilidad a los Servicios de Salud/organización & administración , Humanos , Entrevistas como Asunto , Masculino , Medicaid/normas , Servicios de Salud Mental/organización & administración , Persona de Mediana Edad , Políticas , Pobreza , Autorización Previa/normas , Investigación Cualitativa , Calidad de la Atención de Salud/organización & administración , Proveedores de Redes de Seguridad/organización & administración , Estados Unidos
7.
J Pediatr Adolesc Gynecol ; 32(4): 388-394, 2019 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-30825541

RESUMEN

STUDY OBJECTIVE: Quantitative data suggest that adolescent users of long-acting reversible contraception (LARC), compared with short-acting methods (pill, patch, ring, depot medroxyprogesterone acetate [DMPA]), might be less likely to use condoms. We qualitatively describe and explain adolescent contraceptive users' motivations for condom use, including variation according to contraceptive type. DESIGN: Individual, in-depth qualitative interviews, analyzed thematically. SETTING: Participants were recruited from public family planning clinics and an adolescent medicine clinic, as well as university and other community settings in Atlanta, Georgia. PARTICIPANTS: Sexually active contraceptive users aged 17-19 years old (n = 30), including LARC (n = 10), DMPA (n = 10), and oral contraceptive (n = 10) users. RESULTS: Of the 30 participants, most (n = 25; 83%) used condoms with their more effective contraceptive method, although 11 of 25 used them inconsistently (44%). Oral contraceptive users were particularly motivated to use condoms for pregnancy prevention, because of concerns about contraceptive method efficacy and a desire to be on "the safe side." In contrast, LARC users were primarily motivated by sexually transmitted infection (STI) prevention. DMPA users' motivations were more mixed. Across contraceptive type, factors influencing condom use motivations included sexual health education, personal awareness and/or experience, and perceived consequences and risk. CONCLUSION: Because all participants were using an effective contraceptive method, it is notable that pregnancy prevention was a prominent motivator for using condoms, although LARC users reported STI prevention to be a more important motivation. Parental and school-based sexual health education that clearly addresses STI prevention in addition to pregnancy prevention has the potential to influence condom use motivations and behavior.


Asunto(s)
Condones/estadística & datos numéricos , Conducta Anticonceptiva/estadística & datos numéricos , Anticoncepción/métodos , Conocimientos, Actitudes y Práctica en Salud , Adolescente , Anticoncepción/psicología , Femenino , Georgia , Humanos , Anticoncepción Reversible de Larga Duración/psicología , Masculino , Investigación Cualitativa , Conducta Sexual/psicología , Enfermedades de Transmisión Sexual/prevención & control , Adulto Joven
9.
Vaccine ; 36(24): 3498-3504, 2018 06 07.
Artículo en Inglés | MEDLINE | ID: mdl-29752025

RESUMEN

Vaccination is a safe and effective way to prevent Human Papillomavirus (HPV) infection and related cancers; however, HPV vaccine uptake remains low in the US. After the 2011 Advisory Committee on Immunization Practices (ACIP) recommendation for routine HPV vaccination of adolescent males, several studies have examined predictors for initiating the vaccine series in this population of interest, particularly with regard to provider recommendations. This study examined racial and ethnic differences for HPV vaccine initiation and provider recommendation in male adolescents. Based on prior HPV vaccine uptake estimates and healthcare utilization data, we hypothesized that minority adolescents would be more likely to initiate HPV vaccines, but less likely to receive a provider recommendation compared to white counterparts. We analyzed the 2014 National Immunization Survey-Teen (NIS-Teen), which included 10,753 male adolescents with provider-verified vaccination data in 50 US states, using multivariate logistic regression models to evaluate racial/ethnic differences in HPV vaccine initiation and provider recommendation. The odds of HPV vaccine initiation were 76 percent higher for Hispanic adolescents and 43 percent higher for non-Hispanic Other or Multiple race adolescents compared to white adolescents. Approximately half of parents reported receiving a provider recommendation for vaccination, with no significant difference in the odds of receiving a provider recommendation across racial/ethnic groups. Despite similar frequency of recommendations across racial and ethnic groups, male adolescents who are racial/ethnic minorities are more likely to initiate vaccination. Future research should focus on developing tailored interventions to increase HPV vaccine receipt among males of all racial/ethnic groups.


Asunto(s)
Infecciones por Papillomavirus/etnología , Infecciones por Papillomavirus/prevención & control , Vacunas contra Papillomavirus/administración & dosificación , Derivación y Consulta/estadística & datos numéricos , Vacunación/estadística & datos numéricos , Adolescente , Población Negra , Estudios Transversales , Conocimientos, Actitudes y Práctica en Salud , Hispánicos o Latinos , Humanos , Modelos Logísticos , Masculino , Oportunidad Relativa , Papillomaviridae/inmunología , Infecciones por Papillomavirus/inmunología , Infecciones por Papillomavirus/virología , Estados Unidos/epidemiología , Población Blanca
10.
Contraception ; 2018 Apr 21.
Artículo en Inglés | MEDLINE | ID: mdl-29684327

RESUMEN

OBJECTIVE: Recently there have been calls to strengthen integration of unintended pregnancy and sexually transmitted infection (STI) prevention messages, spurred by increasing use of long-acting reversible contraception. To assess the extent to which public health/clinical messages about unintended pregnancy prevention also address STI prevention, we conducted a content analysis of web-based health promotion information for young people. STUDY DESIGN: Websites identified through a systematic Google search were eligible for inclusion if they were operated by a United States-based organization with a mission related to public health/clinical services and the URL included: 1) original content; 2) about sexual and reproductive health; 3) explicitly for adolescents and/or young adults. Using defined protocols, URLs were screened and content was selected and analyzed thematically. RESULTS: Many of the 32 eligible websites presented information about pregnancy and STI prevention separately. Concurrent discussion of the two topics was often limited to statements about (1) strategies that can prevent both outcomes (abstinence, condoms only, condoms plus moderately or highly effective contraceptive methods) and (2) contraceptive methods that confer no STI protection. We also identified framing of condom use with moderately or highly effective contraceptive methods for back-up pregnancy prevention but not STI prevention. STI prevention methods in addition to condoms, such as STI/HIV testing, vaccination, or pre-exposure or post-exposure prophylaxis, were typically not addressed with pregnancy prevention information. CONCLUSIONS: There may be missed opportunities for promoting STI prevention online in the context of increasing awareness of and access to a full range of contraceptive methods. IMPLICATIONS: Strengthening messages that integrate pregnancy and STI prevention may include: describing STI prevention strategies when noting that birth control methods do not prevent STIs; promoting a full complement of STI prevention strategies; and always connecting condom use to STI prevention, even when promoting condoms for back-up contraception.

11.
J Adolesc Health ; 62(4): 417-423, 2018 04.
Artículo en Inglés | MEDLINE | ID: mdl-29428823

RESUMEN

PURPOSE: Long-acting reversible contraceptive (LARC) methods do not require annual clinic visits for continuation, potentially impacting receipt of recommended sexually transmitted infection (STI)/human immunodeficiency virus (HIV) services for young women. We assess service receipt among new and continuing LARC users versus moderately and less effective method users and non-contraceptors. METHODS: Using 2011-2015 National Survey of Family Growth data from sexually active women aged 15-24 years (n = 2,018), we conducted logistic comparisons of chlamydia, any STI and HIV testing, and sexual risk assessment in the past year by current contraceptive type. RESULTS: Less than half of respondents were tested for chlamydia (40.9%), any STI (47.3%), or HIV (25.9%); 66.5% had their sexual risk assessed. Differences in service receipt between new and continuing LARC users as compared with moderately effective method users were not detected in multivariable models, except that continuing LARC users were less likely to be tested for HIV (adjusted prevalence ratio [aPR] = .52, 95% confidence interval [CI] = .32-.85). New, but not continuing, LARC users were more likely than less effective method users (aPR = 1.35, 95% CI = 1.03-1.76) and non-contraceptors (aPR = 1.43, 95% CI = 1.11-1.85) to have their sexual risk assessed, although both groups were more likely than non-contraceptors to be tested for chlamydia (new: aPR = 1.52, 95% CI = 1.08-2.15; continuing: aPR = 1.69, 95% CI = 1.24-2.29). CONCLUSIONS: We found little evidence that LARC use was associated with lower prevalence of STI testing. However, new, but not continuing, LARC users, as compared with those not using a method requiring a clinic visit, were more likely to have had their risk assessed, suggesting that initiating LARC may offer an opportunity to receive services that does not persist.


Asunto(s)
Infecciones por VIH/diagnóstico , Anticoncepción Reversible de Larga Duración/métodos , Enfermedades de Transmisión Sexual/diagnóstico , Adolescente , Adulto , Femenino , Conductas de Riesgo para la Salud , Humanos , Adulto Joven
12.
J Pediatr Health Care ; 31(2): 203-214, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-27692504

RESUMEN

INTRODUCTION: Medicaid agencies have been promoting the patient-centered medical home (PCMH) model. Most caregivers choose physician practices for their children, and we hypothesized that those following healthier childrearing practices are more likely to seek care in a PCMH. METHOD: We selected children with public insurance plans (n = 20,801) from the 2011-2012 National Survey of Children's Health. We used generalized ordinal logistic regression with state fixed effects to assess the association between home environments and children's use of PCMHs. RESULTS: Children living in the healthiest homes were 1.33 times (p = .001) more likely to receive care from the highest level of PCMH. In states with early PCMH implementation, the odds increased to 2.11 times (p = .001). DISCUSSION: Our results show a significant, sizeable relationship between healthier home environments and the use of PCMH by children from low-income families. They provide implications for assessing the effect of PCMH use on health outcomes and use patterns.


Asunto(s)
Servicios de Salud del Niño , Aceptación de la Atención de Salud/estadística & datos numéricos , Atención Dirigida al Paciente/estadística & datos numéricos , Pobreza/estadística & datos numéricos , Atención Primaria de Salud/estadística & datos numéricos , Adolescente , Adulto , Niño , Servicios de Salud del Niño/economía , Servicios de Salud del Niño/estadística & datos numéricos , Preescolar , Composición Familiar , Femenino , Encuestas de Atención de la Salud , Conocimientos, Actitudes y Práctica en Salud , Humanos , Lactante , Recién Nacido , Masculino , Medicaid/economía , Padres/educación , Padres/psicología , Atención Dirigida al Paciente/economía , Atención Dirigida al Paciente/normas , Relaciones Médico-Paciente , Atención Primaria de Salud/economía , Medio Social , Estados Unidos/epidemiología
13.
Crit Care Med ; 44(7): 1307-13, 2016 07.
Artículo en Inglés | MEDLINE | ID: mdl-26963324

RESUMEN

OBJECTIVES: Literature generally finds no advantages in mortality risk for albumin over cheaper alternatives in many settings. Few studies have combined financial and nonfinancial strategies to reduce albumin overuse. We evaluated the effect of a sequential multifaceted intervention on decreasing albumin use in ICU and explore the effects of different strategies. DESIGN: Prospective prepost cohort study. SETTING: Eight ICUs at two hospitals in an academic healthcare system. PATIENTS: Adult patients admitted to study ICUs from September 2011 to August 2014 (n = 22,004). INTERVENTIONS: Over 2 years, providers in study ICUs participated in an intervention to reduce albumin use involving monthly feedback and explicit financial incentives in the first year and internal guidelines and order process changes in the second year. MEASUREMENTS AND MAIN RESULTS: Outcomes measured were albumin orders per ICU admission, direct albumin costs, and mortality. Mean (SD) utilization decreased 37% from 2.7 orders (6.8) per admission during the baseline to 1.7 orders (4.6) during the intervention (p < 0.001). Regression analysis revealed that the intervention was independently associated with 0.9 fewer orders per admission, a 42% relative decrease. This adjusted effect consisted of an 18% reduction in the probability of using any albumin (p < 0.001) and a 29% reduction in the number of orders per admission among patients receiving any (p < 0.001). Secondary analysis revealed that probability reductions were concurrent with internal guidelines and order process modification while reductions in quantity occurred largely during the financial incentives and feedback period. Estimated cost savings totaled $2.5M during the 2-year intervention. There was no significant difference in ICU or hospital mortality between baseline and intervention. CONCLUSIONS: A sequential intervention achieved significant reductions in ICU albumin use and cost savings without changes in patient outcomes, supporting the combination of financial and nonfinancial strategies to align providers with evidence-based practices.


Asunto(s)
Albúminas/uso terapéutico , Cuidados Críticos , Pautas de la Práctica en Medicina , Adulto , Anciano , Albúminas/economía , Ahorro de Costo , Cuidados Críticos/economía , Revisión de la Utilización de Medicamentos , Femenino , Costos de Hospital , Mortalidad Hospitalaria , Humanos , Unidades de Cuidados Intensivos , Masculino , Persona de Mediana Edad , Pautas de la Práctica en Medicina/economía , Estudios Prospectivos , Análisis de Regresión
14.
Int J Child Adolesc health ; 8(4): 413-423, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26609338

RESUMEN

This project examines how access issues, ethnicity, and geographic region affect vaccination of children by two years of age in Bolivia. Bolivia's rich variation in culture and geography results in unequal healthcare utilization even for basic interventions such as childhood vaccination. This study utilizes secondary data from the 2008 Demographic and Health Survey for Bolivia to examine predictors of vaccination completion in children by two years of age. Using logistic regression methods, we control for health system variables (difficulty getting to a health center and type of health center as well as demographic and socio-economic covariates). The results indicated that children whose parents reported distance as a problem in obtaining health care were less likely to have completed all vaccinations. Ethnicity was not independently statistically significant, however, in a sub-analysis, people from the Quechua ethnic group were more likely to report 'distance as a problem in obtaining healthcare.' Surprisingly, living in a rural environment has a protective effect on completed vaccinations. However, geographic region did predict significant differences in the probability that children would be fully vaccinated; children in the region with the lowest vaccination completion coverage were 80% less likely to have completed vaccination compared to children in the best performing region, which may indicate unequal access and utilization of health services nationally. Further study of regional differences, urbanicity, and distance as a healthcare access problem will help refine implications for the Bolivian health system.

15.
Matern Child Health J ; 19(3): 496-503, 2015 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-24889117

RESUMEN

The American Academy of Pediatrics recommends that children be placed in the supine position on firm bedding and not bed share with parents or other children. Health professionals increasingly understand that many African-American parents do not follow these recommendations, but little research exists on provider reactions to this non-compliance. This study was intended to better understand how low-income, African-American mothers understand and act upon safe sleep recommendations for newborns and how providers counsel these mothers. We conducted focus groups with 60 African-American, low-income, first-time mothers and telephone interviews with 20 providers serving these populations to explore provider counseling and patient decision making. The large majority of mothers reported understanding, but not following, the safe-sleeping recommendations. Key reasons for non-compliance included perceived safety, convenience, quality of infant sleep and conflicting information from family members. Mothers often take measures intended to mitigate risk associated with noncompliance, instead increasing SIDS risk. Providers recognize that many mothers are non-compliant and attribute non-compliance largely to cultural and familial influence. However, few provider attempts are made to mitigate SIDS risks from non-compliant behaviors. We suggest that counseling strategies should be adapted to: (1) provide greater detailed rationale for SIDS prevention recommendations; and (2) incorporate or acknowledge familial and cultural preferences. Ignoring the reasons for sleep decisions by African-American parents may perpetuate ongoing racial/ethnic disparities in SIDS.


Asunto(s)
Negro o Afroamericano , Toma de Decisiones , Conocimientos, Actitudes y Práctica en Salud , Cuidado del Lactante/normas , Madres , Sueño , Muerte Súbita del Lactante/etiología , Adulto , Femenino , Grupos Focales , Humanos , Lactante , Recién Nacido , Cooperación del Paciente , Relaciones Médico-Paciente , Investigación Cualitativa , Factores de Riesgo , Clase Social , Muerte Súbita del Lactante/prevención & control , Posición Supina
16.
Science ; 345(6203): 1515-8, 2014 Sep 19.
Artículo en Inglés | MEDLINE | ID: mdl-25237104

RESUMEN

For proper development, cells must retain patterns of gene expression and repression through cell division. Repression via methylation of histone H3 on Lys27 (H3K27me) by Polycomb repressive complex 2 (PRC2) is conserved, but its transmission is not well understood. Our studies suggest that PRC2 represses the X chromosomes in Caenorhabditis elegans germ cells, and this repression is transmitted to embryos by both sperm and oocytes. By generating embryos containing some chromosomes with and some without H3K27me, we show that, without PRC2, H3K27me is transmitted to daughter chromatids through several rounds of cell division. In embryos with PRC2, a mosaic H3K27me pattern persists through embryogenesis. These results demonstrate that H3K27me and PRC2 each contribute to epigenetically transmitting the memory of repression across generations and during development.


Asunto(s)
Proteínas de Caenorhabditis elegans/metabolismo , Caenorhabditis elegans/embriología , Caenorhabditis elegans/genética , Metilación de ADN , Epigénesis Genética , Regulación del Desarrollo de la Expresión Génica , Histona Demetilasas/metabolismo , Complejo Represivo Polycomb 2/metabolismo , Cromosoma X/genética , Animales , Proteínas de Caenorhabditis elegans/genética , Histona Demetilasas/genética , Masculino , Complejo Represivo Polycomb 2/genética , Espermatozoides/crecimiento & desarrollo , Espermatozoides/metabolismo
17.
Matern Child Health J ; 18(4): 839-51, 2014 May.
Artículo en Inglés | MEDLINE | ID: mdl-23843170

RESUMEN

Identifying the educational and resource needs of new mothers is of paramount importance in developing programs to improve maternal and child health outcomes. The primary purpose of this study was to explore the educational needs of new mothers and identify opportunities to enhance healthcare providers' current educational efforts. A two-part methodology was utilized to qualitatively explore the topic of parenting information needs for new mothers in Georgia. Data collection included information from 11 focus groups with 92 first-time, new mothers and 20 interviews with healthcare providers who serve new mothers. Discussions with both new mothers and providers clearly indicated that new mothers face a significant informational deficit, especially regarding very basic, daily infant care information and health literacy challenges. Educational materials already exist; however, mothers report difficulty accessing and understanding this information. For this reason, both the mothers and the providers stressed a focus on developing programs or interventions that allow in-person education and/or alternative modalities to access information, as opposed to development of new written materials solely. Information from the focus group and interviews provided important insight regarding what improvements need to be made to help new mothers and their families during the early stages of parenthood. By improving the education of new mothers and their families, it is proposed that maternal and infant health status could be improved.


Asunto(s)
Protección a la Infancia , Educación en Salud/métodos , Conocimientos, Actitudes y Práctica en Salud , Cuidado del Lactante/métodos , Responsabilidad Parental , Adolescente , Adulto , Preescolar , Bases de Datos Factuales , Escolaridad , Estudios de Evaluación como Asunto , Femenino , Grupos Focales , Georgia , Personal de Salud , Humanos , Lactante , Recién Nacido , Entrevistas como Asunto , Relaciones Madre-Hijo , Evaluación de Necesidades , Medición de Riesgo , Factores Socioeconómicos , Adulto Joven
18.
Nicotine Tob Res ; 16(6): 689-96, 2014 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-24376279

RESUMEN

INTRODUCTION: A rapidly growing number of U.S. employers are charging health insurance surcharges for tobacco use to their employees. Despite their potential to price-discriminate, little systematic empirical evidence of the impacts of these tobacco surcharges has been published. We attempted to assess the impact of a health insurance surcharge for tobacco use on cessation among enrollees in Georgia's State Health Benefit Plan (GSHBP). METHODS: We identified a group of enrollees in GSHBP who began paying the tobacco surcharge at the program's inception in July 2005. We examined the proportion of these enrollees who certified themselves and their family members as tobacco-free and no longer paid the surcharge through April 2011, and we defined this as implied cessation. We compared this proportion to a national expected annual 2.6% cessation rate. We also compared our observation group to a comparison group to assess surcharge avoidance. RESULTS: By April 2011, 45% of enrollees who paid a tobacco surcharge starting in July 2005 had certified themselves as tobacco-free. This proportion exceeded the expected cessation based on 3 times the national rate (p < .001). The length of enrollment was not statistically different between our observation and comparison groups (p = .427). CONCLUSIONS: The reported rates of tobacco cessation among GSHBP enrollees resulting from a tobacco surcharge substantially exceed national rates. These surcharges appear to be effective, but the value of these results, and the effectiveness of health insurance surcharges in changing behavior, are tempered by the important limitation that enrollees' certification of quitting was self-reported and not subject to additional, clinical verification.


Asunto(s)
Honorarios y Precios , Planes de Asistencia Médica para Empleados/economía , Promoción de la Salud/métodos , Cese del Uso de Tabaco/estadística & datos numéricos , Tabaquismo/economía , Adulto , Estudios de Cohortes , Femenino , Georgia/epidemiología , Humanos , Masculino , Persona de Mediana Edad , Fumar , Tabaquismo/epidemiología
19.
JAMA Psychiatry ; 70(12): 1355-62, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-24154931

RESUMEN

IMPORTANCE: The passage of the 2008 Mental Health Parity and Addiction Equity Act and the 2010 Affordable Care Act incorporated parity for substance use disorder (SUD) treatment into federal legislation. However, prior research provides us with scant evidence as to whether federal parity legislation will hold the potential for improving access to SUD treatment. OBJECTIVE: To examine the effect of state-level SUD parity laws on state-aggregate SUD treatment rates and to shed light on the impact of the recent federal SUD parity legislation. DESIGN, SETTING, AND PARTICIPANTS: We conducted a quasi-experimental study using a 2-way (state and year) fixed-effect method. We included all known specialty SUD treatment facilities in the United States and examined treatment rates from October 1, 2000, through March 31, 2008. Our main source of data was the National Survey of Substance Abuse Treatment Services, which provides facility-level information on specialty SUD treatment. INTERVENTIONS: State-level SUD parity laws during the study period. MAIN OUTCOMES AND MEASURES: State-aggregate SUD treatment rates in (1) all specialty SUD treatment facilities and (2) specialty SUD treatment facilities accepting private insurance. RESULTS: The implementation of any SUD parity law increased the treatment rate by 9% (P < .001) in all specialty SUD treatment facilities and by 15% (P = .02) in facilities accepting private insurance. Full parity and parity only if SUD coverage is offered increased the SUD treatment rate by 13% (P = .02) and 8% (P = .04), respectively, in all facilities and by 21% (P = .03) and 10% (P = .04), respectively, in facilities accepting private insurance. CONCLUSIONS AND RELEVANCE: We found a positive effect of the implementation of state SUD parity legislation on access to specialty SUD treatment. Furthermore, the positive association is more pronounced in states with more comprehensive parity laws. Our findings suggest that federal parity legislation holds the potential to improve access to SUD treatment.


Asunto(s)
Seguro de Salud/legislación & jurisprudencia , Salud Mental/legislación & jurisprudencia , Centros de Tratamiento de Abuso de Sustancias/legislación & jurisprudencia , Trastornos Relacionados con Sustancias/terapia , Encuestas Epidemiológicas/estadística & datos numéricos , Humanos , Seguro de Salud/estadística & datos numéricos , Salud Mental/estadística & datos numéricos , Patient Protection and Affordable Care Act/legislación & jurisprudencia , Patient Protection and Affordable Care Act/estadística & datos numéricos , Centros de Tratamiento de Abuso de Sustancias/estadística & datos numéricos , Estados Unidos , United States Substance Abuse and Mental Health Services Administration/legislación & jurisprudencia , United States Substance Abuse and Mental Health Services Administration/estadística & datos numéricos
20.
J Am Acad Child Adolesc Psychiatry ; 52(9): 953-60, 2013 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-23972697

RESUMEN

OBJECTIVE: The goals of this study were to identify treatment rates among adolescents with co-occurring major depressive episode (MDE) and substance use disorder (SUD), and to examine the role of health insurance in the treatment of these disorders. METHOD: Seven years of cross-sectional data (2004-2010) were pooled from the National Survey on Drug Use and Health to derive a nationally representative sample of 2,111 adolescents who had both a past-year MDE and SUD and whose insurance status was known. The associations of public and private insurance with MDE and SUD treatment were examined using multinomial logistic regressions that controlled for health status and sociodemographic variables. RESULTS: Less than one-half (48%) of adolescents received any form of MDE treatment in the past year, and only 10% received any form of SUD treatment. Only 16% of adolescents who received MDE treatment also received SUD treatment. Relative to no insurance, public insurance was associated with an increased likelihood of receiving MDE treatment alone, but not with an increased likelihood of receiving both MDE and SUD treatment. Involvement in the criminal justice system was the major factor affecting the likelihood that an adolescent would receive both MDE and SUD treatment, as opposed to either no treatment or treatment for MDE alone. CONCLUSIONS: Exceptionally low rates of SUD treatment were observed in this high-risk sample. Study findings highlight a missed opportunity to assess and to treat SUD among adolescents with co-occurring MDE and SUD who have received some form of MDE treatment in the past year.


Asunto(s)
Alcoholismo/rehabilitación , Trastorno Depresivo Mayor/rehabilitación , Drogas Ilícitas , Cobertura del Seguro/estadística & datos numéricos , Seguro Psiquiátrico/estadística & datos numéricos , Trastornos Relacionados con Sustancias/rehabilitación , Adolescente , Alcoholismo/diagnóstico , Alcoholismo/epidemiología , Alcoholismo/psicología , Niño , Terapia Combinada , Comorbilidad , Estudios Transversales , Trastorno Depresivo Mayor/diagnóstico , Trastorno Depresivo Mayor/epidemiología , Trastorno Depresivo Mayor/psicología , Femenino , Accesibilidad a los Servicios de Salud/estadística & datos numéricos , Encuestas Epidemiológicas , Humanos , Masculino , Trastornos Relacionados con Sustancias/diagnóstico , Trastornos Relacionados con Sustancias/epidemiología , Trastornos Relacionados con Sustancias/psicología
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