Understanding the national evidence on the double burden of malnutrition in Ethiopia for the implications of research gap identifications: a scoping review.

BACKGROUND: Owing to the unavoidable consequences of nutritional transition, the double burden of malnutrition (DBM) is an emerging public health problem. An increasing number of studies have found that Ethiopians face a DBM. However, country-level evidence has not yet been summarised using a scoping review study design. OBJECTIVE: The main objective of this review was to map the national evidence on DBM in Ethiopia for the implications of research gap identifications. ELIGIBILITY CRITERIA: The population, concept and context approach was used. All age groups, box sexes, all dates of publication and articles in English language focused on DBM conducted in Ethiopia were included. SOURCES OF EVIDENCE: Primary research articles, systematic reviews, meta-analyses and scoping reviews searched from electronic databases such as PubMed, ScienceDirect, Cochrane Library, Wiley Online Library, Google Scholar and Google were the sources of evidence. CHARTING METHODS: The Joanna Briggs Institute Reviewer's manual was used as a review methodology. The authors, publication year, region, study design, sample size, population group, measured outcomes and main findings were charted in a table. RESULTS: A total of 35 articles met the inclusion criteria among 124 426 participants. The average summarised prevalence of DBM was 33.6%, with the average proportions of undernutrition and overnutrition at 21.5% and 12.1%, respectively. The major factors that influenced the DBM were categorised as child, maternal, adolescent, household and adult-related factors. CONCLUSION: In Ethiopia, the overall prevalence of DBM is high, which makes one-third of the population affected by DBM. The foremost determinant factors that influenced the DBM were characterised as child, maternal, adolescent, household and adult-related factors. Therefore, a double-duty interventions should be used to address DBM, considering multilevel factors at the individual, community and societal levels. PROTOCOL REGISTRATION: This review was registered on the figshare website on 28 February 2021, with DOI number https://doi.org/10.6084/m9.figshare.14131874. The review protocol was published with a DOI number http://dx.doi.org/10.1136/bmjopen-2021-050805.

Double burden of malnutrition and its associated factors among adolescents in Debre Berhan Regiopolitan City, Ethiopia: a multinomial regression model analysis.

Background: The double burden of malnutrition (DBM), contained both undernutrition and overnutrition, is a growing public health concern that presents a significant challenge to the food and nutrition policies of developing nations such as Ethiopia. However, the prevalence and contributing factors of DBM among adolescents in the study area have not been adequately investigated by Ethiopian researchers. Therefore, this study aims to determine the prevalence of DBM and contributing factors among secondary school students in Debre Berhan City, Ethiopia. Methods: A school-based cross-sectional study was conducted among 742 adolescents aged 10-19 years from October 13, 2022, to November 14, 2022, using a multi-stage sampling method. Data were collected using the online Kobo toolbox tool. A multinomial logistic regression model was used to analyze the data. The data were cleaned and analyzed in R software 4.2.2. Adolescents who had body mass index for age Z score (BAZ) < -2 SD, > +1 SD, and > +2 from the median value were considered thin, overweight, and obese, respectively. Results: The overall prevalence of DBM was 21.5% (14.8% thinness and 6.7% overweight/obesity). In the multivariable multinomial logistic regression analysis models factors such as age [AOR = 0.79, 95% CL: (0.67, 0.93)], sex [AOR = 3.86, 95% CL: (2.35, 6.32)], school type [AOR 5.03, 95% CL: (2.30, 10.99)], minimum dietary diversity score [AOR = 2.29, 95% CL: (1.27, 4.14)], frequency of meals [AOR = 2.09, 95% CL: (1.13, 3.89)], home gardening practice [AOR = 2.31, 95% CL: (1.44, 3.67)], history of illness [AOR = 0.57, 95% CL: (0.36, 0.93)], and knowledge of nutrition [AOR = 4.96, 95% CL: (1.61, 15.33)] were the significant predictors of either thinness or overweight/obesity (DBM). Conclusion: More than one-fifth of adolescents were affected by DBM in the study area. This prevalence is higher compared with the national and regional prevalence that found to be a public health concern. Thus, interventions like double-duty interventions should consider the age, sex, school type, minimum dietary diversity score, frequency of meals, home gardening practice, history of illness, and nutritional knowledge of adolescents. Clinical Trial Registration: clinicaltrial.gov, identifier NCT05574842.

Incidence of tuberculosis and its predictors among under-five children with severe acute malnutrition in North Shoa, Amhara region, Ethiopia: a retrospective follow-up study.

Introduction: Although tuberculosis (TB) is one of the significant public health challenges in severely malnourished children throughout the globe, it is a severe issue for countries such as Ethiopia, with significant resource limitations. Few studies have examined the incidence of tuberculosis and its predictors among children under five years of age with severe acute malnutrition in developing countries, and there is a paucity of data. This study aimed to estimate the incidence of tuberculosis and its predictors among under-five children with severe acute malnutrition (SAM) in North Shoa, Amhara region, Ethiopia. Methods: An institution-based retrospective follow-up study was conducted between January 20, 2017, and June 20, 2019. The sample size was calculated using STATA, which yields a total of 345 charts that were selected with systematic random sampling. Data entry was performed using Epi-data version 4.2 and analyzed with STATA 14. Kaplan-Meier survival curves were computed. Cox proportional hazard models were fitted to detect the determinants of tuberculosis. The hazard ratio with a 95% confidence interval was subsequently calculated. Variables with p-values < 0.05 were considered statistically significant. Results: The incidence rate of tuberculosis among children under five years of age with SAM was 4.6 per 100 person-day observations (95% CI: 3.29, 8.9). Predictors of TB were a history of contact with known TB cases [AHR: 1.4 (95% CI: 1.00, 2.8], HIV/AIDS [AHR: 3.71 (95% CI: 2.10, 8.71)], baseline pneumonia [AHR: 2.10 (1.76,12)], not supplying zinc at baseline [AHR: 3.1 (1.91, 4.70)], and failed appetite taste at the diagnosis of SAM [AHR: 2.4 (1.35, 3.82)]. Conclusions: In this study, the incidence rate of TB was high. Not supplying zinc at baseline, failed appetite taste at the diagnosis of SAM, history of contact with known TB cases, and baseline pneumonia were significant predictors of TB. Prioritizing regular TB screenings, nutritional support, and zinc supplementation for under-five children with SAM should be implemented to reduce the risk of TB.

Level and Predictors of Minimum Dietary Diversity Among Pregnant Women in Eastern Ethiopia: Evidence From Facility-Based Cross-sectional Survey.

Low dietary diversity is one of the most serious public health issues in developing countries, resulting in poor nutritional status, particularly vitamin and mineral deficiencies in pregnant women. However, there is insufficient information on the current status of pregnant women's minimum dietary diversity in Eastern Ethiopia. The main aim of this study is to assess the level and predictors of minimum dietary diversity among pregnant women in Harar Town, Eastern Ethiopia. The study was conducted on 471 women using a health institution-based cross-sectional study design from January to March 2018. A systematic random sampling method was used to select the study participants. A pretested and structured questionnaire was used to collect data on the minimum dietary diversity. A logistic regression model was used to assess the relationship between the outcome variable and the independent variables. A P-value of .05 was used to indicate statistical significance. The proportion of pregnant women who had adequate minimum dietary diversity was 52.7% (95% CI: (47.9%, 57.6)). Urban residence [(AOR = 0.08, 95% CI: (0.02, 0.33)], smaller family size [(AOR = 7.28, 95% CI: (3.25, 16.28)], husband occupation [(AOR = 2.55, 95% CI: (1.39, 4.6)], husband support [(AOR = 3.85; 95% CI: (1.23, 12.02)], having more than 1 dwelling room [(AOR = 5.7, 95% CI: (2.32, 13.8) and medium wealth quantile [AOR = 1.93, 95% CI: (1.13.39)] were associated with adequate minimum dietary diversity. The level of minimum dietary diversity was low in the study area. It was linked to urban residency, smaller family sizes, husband employment, husband support, having more than 1 bedroom, and medium wealth quantile. Efforts should be made to improve husband support, wealth index, husband occupation, and food security status in order to boost mothers' minimal dietary diversity.

Modeling on number of children ever born and its determinants among married women of reproductive age in Ethiopia: A Poisson regression analysis.

Background: One of the main components of population dynamics that determine the size, structure, and composition of a country's population is the number of ever-born children. Psychological, economic, social, and demographic factors all have a strong influence on and predict it. However, there is little information on its current status in Ethiopia. As a result, modeling the number of children ever born and its determinants is critical for the Ethiopian government to develop appropriate policies and programs. Methods: A total of 3260 eligible women were used as a study sample in this study to assess the number of children ever born and determinants among married reproductive age women in Ethiopia. Secondary data were culled from the 2019 Ethiopian Demography and Health Survey datasets. The factors associated with the number of children born were identified using a Poisson regression model (CEB). Results: The average number of children per mother was 6.09, with a standard deviation of 8.74. There were 2432 (74.6%) rural residents among the total respondents, 2402 (73.7%) have no formal education, and three out of five women are not currently working. The participants' average age was 41.66, with a standard deviation of 3.88. When compared to urban residents, the number of CEB for rural residents is 1.37 times higher. When compared to women with no education, the number of CEB for women with higher education was reduced by 48%. For every unit increase in respondents' current age, the percent change in the number of children ever born increases by 2.4%. For every unit increase in the family's wealth index status, the percent change in the number of children ever born decreases by 1.7%. Conclusion: When compared to the target of Ethiopia's health transformation plan, the average number of children born is higher. Improving the household wealth index, women's education, and employment status all contribute to a reduction in the number of CEB, which is important in balancing population growth with natural capacity and the country's economic development.

Lived Experience and Perceptions of Adolescents on Prevention, Causes and Consequences of Double Burden of Malnutrition in Debre Berhan City, Ethiopia: A Qualitative Study.

Background: The coexistence of undernutrition, overweight, and obesity within the same households and populations is recognized as the Double Burden of Malnutrition (DBM). A paradigm shift thinking is needed to mitigate its impact. School adolescents are the most vulnerable groups to DBM. However, lived experiences and perceptions on prevention, causes, and consequences of DBM were not well studied. Therefore, this study aims to explore the lived experiences and perceptions of adolescents about the prevention, causes, and consequences of DBM in Ethiopia. Methods: A qualitative research method using phenomenology design was conducted among 20 purposively selected participants from private and government schools from June 3 to July 10, 2022. The further sampling process was guided by a saturation of ideas. In-depth and key informant interviews were conducted to collect the data. The most recent version of Open code 4.03 was utilized to generate meaningful codes, subthemes, and themes. The results were displayed using thematic analysis and respondents' well-spoken verbatims. Results: The study explored the perceptions of adolescents on the causes, prevention, and consequences of DBM. The main causes of DBM identified were poor dietary and drinking habits, poor knowledge and attitude about nutrition, low financial income, unemployment, food insecurity, poor feeding culture, physical inactivity, poor food management, educational and school-related issues, national-related issues, frequent use of ultra-processed foods, and frequent out of home eating. The majority of students were not aware of how DBM will affect their health and academic performance over the long run. Conclusion: The findings showed that despite school adolescents' variations in knowledge, lived experience, attitude, and perceptions, most of them have a poor understanding of the causes, consequences, and prevention mechanisms of the double burden of malnutrition. The results suggest the need for instituting double-duty interventions that have a double impact on the prevention of DBM.

Food taboos and associated factors among agro-pastoralist pregnant women: A community-based cross-sectional study in Eastern Ethiopia.

In underdeveloped nations, cultural norms that are harmful to women's health, such as food taboos, are responsible for five to fifteen percent of pregnancy-related deaths. Food Taboo traditions prevent women from consuming particular foods, which reduces dietary diversity and food quality and may have detrimental nutritional effects. However, little is known about Ethiopia's dietary taboos and related issues. So, the purpose of this study was to find out how common food taboos are among pregnant women in agro pastoralist settings, as well as the accompanying factors. 636 pregnant women were enrolled in a community-based cross-sectional study using a two-stage cluster sampling strategy, distributed over seven clusters. Data were exported from Epi Data version 3.01 to Statistical Package for Social Science version 20 after being entered. The prevalence of dietary taboos in this study was 67.4% (95% CI: 63.7%, 71.1%). Food taboos were independently and significantly predicted by lack of formal education [AOR = 1.97 (95% CI: 1.583, 4.496), low wealth index [AOR = 2.26 (95% CI: 1.173, 4.353)], absence of antenatal care visits [AOR = 6.16 (95% CI: 4.996, 10.128), lack of knowledge of maternal nutrition [AOR = 4.94 (95% CI: 3.799, 8.748)], and negative attitude toward maternal nutrition [ In the research area, dietary taboos were very common. Food taboos were independently predicted by low wealth index, lack of maternity care visits, lack of formal education, ignorance of maternal nutrition, and unfavorable attitudes. Therefore, it is highly advised that strong community-based maternal nutrition education and counseling, raising women's income, and preparing young women for study in order to improve their educational standing be implemented.

Ethiopian women's breast cancer self-examination practices and associated factors. A systematic review and meta-analysis.

BACKGROUND: Breast neoplasm is the most frequently diagnosed and the leading cause of cancer death in the vast majority of the countries. Breast cancer self-examination is a check-up of a woman does at home to look for changes or problems in the breast tissue. The benefit of early recognition is for early treatment that is more effective, higher long-term survival rates and better quality of life. The aim of this review was to determine the pooled prevalence of breast cancer self-examination practice and identify its associated factors among Ethiopian women. METHODS: Google Scholar, PubMed, Science Direct, web of science, and Cochrane Library were used for search of articles. This review includes thirty four articles conducted in Ethiopia between 2011 and 2020. The review contains 14,908 women to determine the ever pooled prevalence of breast cancer self-examination practice. Health workers and students made up 28.35% of the total participants. Data were extracted using a standardized data extraction format prepared in Microsoft Excel and analyzed with Stata 14. To assess heterogeneity I2 test were used. A random effect meta-analysis model was used to estimate the pooled breast cancer self-examination (BCSE) practice of Ethiopian women. Moreover associated factors were also assessed. RESULTS: In Ethiopian women, the overall ever and regular pooled breast cancer self-examination practice was 36% (95% CI: 28, 43) and 16% (95% CI: 28, 43) respectively. The ever pooled prevalence for health workers or students was 53% (95% CI: 41, 65), whereas for other participants it was 25% (95% CI: 19, 30). Good knowledge about breast self-examination (AOR: 3.69: 95% CI: 2.70, 5.05), positive attitude towards BCSE (AOR: 2.72: 95% CI: 1.74, 4.24), Getting to know people with breast cancer(AOR: 2.77: 95% CI: 1.51, 5.09), family history of breast cancer (AOR: 2.49: 95% CI: 1.60, 3.88) and personal history of breast cancer (AOR: 2.26: 95% CI: 1.70, 3.01) were associated factors to BCSE practice among Ethiopian women. All of the studies included in this review were conducted in a cross-sectional design was a limitation of this review and meta-analysis. CONCLUSION: This review and meta-analysis showed the ever and regular pooled prevalence of BCSE among Ethiopian women. More than one third of Ethiopian women ever practiced BCSE. We recommend that awareness creation should be perform in order to tackle the risk of breast cancer.

Prevalence and associated factors of anemia among adolescent girls in Ethiopia: A systematic review and meta-analysis.

BACKGROUND: Anemia is the reduction of red blood cells in size and numbers and an indicator of both poor nutrition and poor health. It is a major global public health problem. Anemia in adolescents and young adults can have negative effects on their cognitive performance and growth. In Ethiopia, previous studies yielded variable prevalence. This review aimed to determine the pooled prevalence of adolescent girls' anemia and associated factors in Ethiopia. METHODS: We searched for studies reporting anemia and associated factors among adolescent girls as reported in peer reviews publications in Ethiopia from 1988 to 2021 from PubMed, Google Scholar, Web of Science, Science Direct, Cochrane Library, and Worldwide Science database. The search strategy identified 309 cross-sectional studies. After screening for potentially eligible articles, we identified 37 publications for full text review, following which 10 publications were included in the final review. Using data from the review, we performed meta-analysis to produce pooled estimates and assess the prevalence of anemia and associated risk factors. Data were extracted using a standardized data extraction format prepared in Microsoft Excel™ and transferred to Stata ™ Version 14.0 for management and further analysis. To identify the source of heterogeneity, subgroup analysis using sample size and study setup was computed, and I2 test was used to declare the presence or absence of significant heterogeneity during subgroup analysis. A random-effect meta-analysis model was used to estimate the pooled prevalence of adolescent girls' anemia. Moreover associated factors for adolescent anemia were assessed too. RESULTS: The overall pooled prevalence of anemia among adolescent girls' in Ethiopia was 23.02% (95% CI: 17.21to 28.84). In the subgroup analysis, studies that have a higher sample size than mean have a higher pooled prevalence (27.35%) (95% CI: 21.42 to 33.28) compared to their counterparts. Age being 15-19 (OR: 2.13; 95% CI: 1.52 to 2.96), living in rural areas (OR: 2.05; 95% CI: 1.66 to 2.54), and low dietary diversity (OR: 1.35; 95% CI: 1.00 to 2.34), were the identified factors associated with anemia among adolescent girls'. CONCLUSION: The pooled prevalence of anemia among adolescent girls in Ethiopia was moderately high. Being in 15-19 years, rural residence, and low dietary diversity score were found to be the significant factors of anemia among adolescent girls in Ethiopia.

Factors associated with childhood underweight among orphaned preschool children: A community-based analytical cross-sectional study in Southern Ethiopia.

BACKGROUND: Childhood underweight is one of the major public health problems in Ethiopia. In Ethiopia, most of the available evidence is related to the general community children, which had different risk and severity levels than orphan children. Even though under-five orphan children have a higher risk of being underweight, they are the most neglected population. OBJECTIVE: The study aims to determine the prevalence and factors associated with childhood underweight among orphaned preschool children in Southern Ethiopia. METHODS: A community-based analytical cross-sectional study was conducted among 367 orphans. The burden of childhood underweight was assessed using World Health Organization standard cutoff points below -2 SD using z-scores. All variables with a p-value of < 0.25 during binary logistic regression analysis were entered into a multivariate logistic regression analysis to identify predictor variables independently associated with underweight at a p-value of 0.05 with 95% CI. RESULTS: In this study, the prevalence of underweight among orphan children was 27.4%. The main factors associated with underweight were female child (adjusted odds ratio (aOR) = 5.29, 95% confidence interval (CI) (2.83-9.92)), adult food as type of first complementary food (aOR = 2.47; 95% CI (1.24-4.94)), food insecurity (aOR = 1.98; 95% CI (1.23-3.21)), and child age from 24-59 months (aOR = 7.19; 95% CI (3.81-13.60)). CONCLUSION: Childhood underweight is a public health problem in the study area. The sex of a child, type of first complementary food, household food security status, and child age were the major predictors of underweight. Therefore, appropriate dietary interventions, nutrition education, and increased food security status of orphan children are highly recommended.

Mapping the national evidence on double burden of malnutrition in Ethiopia: a protocol of scoping review.

INTRODUCTION: Currently, the double burden of malnutrition (DBM) is an emerging public health problem due to the inevitable consequences of nutritional transition. An increasing number of studies have reported the DBM in Ethiopian populations. However, organised and summarised national evidence is not yet available. Therefore, the main aim and research question of this scoping review is to map the national evidence on the DBM in the last decades in Ethiopia. METHODS: This scoping review will be mapping the national evidence on the DBM in different population groups of Ethiopia including all ages and both sexes from 1 January 2021 to 30 September 2021. The Joanna Briggs Institute Reviewer's Manual will be used as the methodology of review for this review. The search strategy will be conducted using electronic databases such as PubMed, ScienceDirect, Cochrane Library, Wiley Online Library, Google Scholar, and grey literature sources and reference lists of key studies to identify studies appropriate for inclusion in the review. Two independent reviewers will be screened independently with all abstracts and full-text studies for inclusion. Data will be abstracted into tables and logically organised according to the items addressed in the specific research questions. ETHICS AND DISSEMINATION: The data will be used from publicly available secondary sources. Therefore, no ethical review and approval will be required for this review. Dissemination of results will be sought through peer-reviewed publications, conference presentations and stakeholder meetings. Regarding registration, this review protocol is registered on the figshare website on 28 February 2021, with the DOI number https://doiorg/106084/m9figshare14131874.

Thrombocytopenia and Associated Factors Among HIV Infected Patients in Pre- and Post-Anti-Retroviral Therapy, North East Ethiopia.

BACKGROUND: Thrombocytopenia is a common disorder of HIV (human immunodeficiency virus) infection. The magnitude of thrombocytopenia and associated factors among HIV-infected patients receiving ART (anti-retroviral treatment) are not studied well in this study area. The aim of this study was to determine the prevalence of thrombocytopenia and associated factors in pre- and post-ART patients who attended Debre Berhan Referral Hospital (DBRH) in North-East Ethiopia. METHODS: A hospital-based cross-sectional study was conducted from October to December 2020 in DBRH, North-East Ethiopia. From the total ART patients, 272 study participants were selected randomly. Socio-demographic variables and clinical characteristics of the patients were collected by standard questionnaires. Measurement of platelet count and CD4 count were made by Sysmex XT2000i hematology machine and BD FACS count analyzer, respectively. Data were analyzed with SPSS software version 23 and multivariate logistic regression was done. P-value less than 0.05 was taken as statistically significant. RESULTS: The prevalence of thrombocytopenia was 22.7% with 95% CI: 17.8-27.5 in pre-ART and 14.7% with 95% CI: 11.0-19.9 in post-ART HIV-infected patients with a significant difference at P <0.0001. HIV patients with CD4 counts <200 cells/µL were more likely to have thrombocytopenia (35.0%) than patients with CD4 counts ≥200 with a P <0.04 in pre-ART patients. Patients on zidovudine (AZT)-based therapy were more likely to have thrombocytopenia (16.3%) than patients on tenofovir (TDF)-based therapy (14.8%) with P<0.79; however, this did not show any significant association. CONCLUSION: The prevalence of thrombocytopenia decreased significantly after the beginning of ART. HIV patients with low CD4 count and on AZT-based treatment showed high risk of thrombocytopenia. According to this study, thrombocytopenic patients were observed even after the initiation of ART. As a result, to decrease thrombocytopenic associated mortality and morbidity, there should be continuous screening for HIV-infected patients.

Predictors of Service Satisfaction Among Clients Receiving Antiretroviral Therapy Services at Public Hospitals in Eastern Ethiopia.

BACKGROUND: The issue of service satisfaction with antiretroviral therapy services needs more attention as it indicates the outcome of quality health services. Although different studies have been conducted on client satisfaction in different countries, there is limited evidence on the major predictors of client satisfaction with ART services in Ethiopia. OBJECTIVE: To assess the predictors of service satisfaction among clients receiving antiretroviral therapy services at a public hospital in Harar Town, Eastern Ethiopia. METHODS: A hospital-based cross-sectional study design was employed among 413 antiretroviral therapy clients from February to March 2018. The data were cleaned and entered into EpiData version 3.1 and exported to SPSS version 21 for analysis. A five-point Likert scale was used to assess client satisfaction with the ART services. Clients who scored ≥75% of the items were categorized as "satisfied" and those who scored <75% of the items were categorized as "dissatisfied". Independent variables with a p-value of ≤0.25 in the binary regression analysis were included in the multivariate logistic regression analysis to control confounding factors. Statistical significance was set at a p-value less than 0.05. RESULTS: The overall client satisfaction with ART services was 76.9% (95% CI: 72.6, 80.6). Regarding the predictors, clients who were not attending formal education [(AOR=3.7, 95% CI: 1.75,8.12)] and primary education [(AOR=3.9, 95% CI: 1.66,9.32)], low wealth index [(AOR=2.8, 95% CI: 1.27, 6.28)], longer duration of treatment [(AOR=2.7, 95% CI: 1.46, 5.5.20)], shorter waiting time [(AOR=5.4, 95% CI: 2.52, 11.57)], disclosure of serostatus of HIV [(AOR=3.7, 95% CI: 1.59, 8.49)], seen by the same health care providers repeatedly [(AOR=2.0, 95% CI: 1.06, 3.82)], loss of medical records [(AOR=0.26, 95% CI: 0.13,0.50)] and social supports [(AOR=2.3, 95% CI: 1.12,4.63)] were significantly associated with service satisfaction on antiretroviral therapy services. CONCLUSION: Overall client satisfaction with ART services was relatively low in the study area. However, not attending formal and primary education, low wealth index, longer duration of treatment, shorter waiting time, disclosure of serostatus, seen by the same health care providers, loss of medical records, and social support were independent predictors of client satisfaction.

The Burden of Adverse Neonatal Outcome among Antenatal Substance Users in Ethiopia: A Systematic Review and Meta-Analysis.

Background. Substances mainly khat, alcohol and cigarette are used during pregnancy in Ethiopia. However, to this date, there is no pooled evidence about the burden of adverse neonatal outcomes among the substance users during pregnancy in the country. Methods. Eligible primary studies were accessed from 4 international data bases (Google Scholar, Science Direct, Scopus, and PubMed). The required data were extracted from these studies and then exported to stata version 14 for analysis. Subgroup analyses were conducted for evidence of heterogeneity. Results. A total of 2298 neonates were included from 7 studies. Among these neonates, 530(23.06%) were those whose mothers used substance during pregnancy (exposed group) whereas 1768 neonates were those whose mothers didn't use substance during pregnancy (controls group). The pooled prevalence of adverse neonatal outcome among the exposed mothers was 38.32% (95% CI: 29.48%, 47.16%; I2 = 76.3%) whereas it was 16.29% (95% CI: 9.45%, 23.13%) among the controls. Adverse neonatal outcome was most burdensome among cigarette smokers 45.20% (95% CI: 37.68%, 52.73%; I2 = .00%) when compared with khat chewers 34.00% (95% CI: 20.87%, 47.13%) and alcohol drinkers 38.47% (95% CI: 17.96%, 58.98%). Low birth weight 42.00% (95% CI: 18.01%, 65.99%; I2 = 91.8%) was the most common adverse birth outcome. Conclusion. It was found that adverse neonatal outcomes were much more burdensome among antenatal substance users than the controls. Therefore, mothers should be enabled to quit using substance before pregnancy. Besides, strict comprehensive screening of every pregnant mother should be made at antenatal care clinics for early identification and management of antenatal substance use.

Minimum acceptable diet and associated factors among infants and young children aged 6-23 months in Amhara region, Central Ethiopia: community-based cross-sectional study.

OBJECTIVE: The main objective of this study was to assess the prevalence of a minimum acceptable diet (MAD) and associated factors. DESIGN: Community-based cross-sectional study SETTING: Debre Berhan Town, Ethiopia. PARTICIPANTS: An aggregate of 531 infants and young children mother/caregiver pairs participated in this study. A one-stage cluster sampling method was used to select study participants and clusters were selected using a lottery method. Descriptive statistics were calculated for all study variables. Statistical analysis was performed on data to determine which variables are associated with MAD and the results of the adjusted OR with 95% CI. P value of <0.05 considered statistically significant. PRIMARY OUTCOME: Prevalence of MAD and associated factors RESULTS: The overall prevalence of MAD was 31.6% (95% CI: 27.7 to 35.2). Having mother attending secondary (adjusted OR, AOR=4.9, 95% CI: 1.3 to 18.9) and college education (AOR=6.4, 95% CI: 1.5 to 26.6), paternal primary education (AOR=1.3, 95% CI: 1.5 to 2.4), grouped in the aged group of 12-17 months (AOR=1.8, 95% CI: (1.0 to 3.4) and 18-23 months (AOR=2.2, 95% CI: 1.2 to 3.9), having four antenatal care (ANC) visits (AOR=2.0, 95% CI: 1.0 to 3.9), utilising growth monitoring (AOR=1.8, 95% CI: 1.1 to 2.9), no history of illness 2 weeks before the survey (AOR=2.9, 95% CI: 1.5 to 6.0) and living in the household with home garden (AOR=2.5, 95% CI: 1.5 to 4.3) were positively associated with increase the odds of MAD. CONCLUSION: Generally, the result of this study showed that the prevalence of minimum acceptable was very low. Parent educational status, ANC visits, infant and young child feeding advice, child growth monitoring practice, age of a child, a child has no history of illness 2 weeks before the survey, and home gardening practice were the predictors of MAD. Therefore, comprehensive intervention strategies suitable to the local context are required to improve the provision of MAD.

Prevalence of Goiter and Associated Factors among Women of Reproductive Age Group in Demba Gofa Woreda, Gamo Gofa Zone, Southwest Ethiopia: A Community-Based Cross-Sectional Study.

BACKGROUND: Iodine deficiency disorder is a major public health problem in Ethiopia that is more common in women of reproductive age. However, it is not well addressed and there is a lack of information on its prevalence and associated factors in women of reproductive age group. Therefore, the objective of this study was to assess goiter prevalence and associated factors among women of reproductive age in the Demba Gofa woreda, Gamo Gofa Zone, Southwest Ethiopia. METHODS: A community-based cross-sectional study was used among 584 randomly selected women in the reproductive age group from February 05 to April 20, 2016. A simple random sampling technique was used to select the study kebeles, and a systematic random sampling technique was used to select the study samples. Data were collected through a pretested questionnaire, and the goiter examination was done clinically for each participant. The collected data were coded and entered into a computer for statistical analysis using EpiData version 3.2 and analyzed using SPSS version 20. Variables with a P value ≤0.25 in bivariate logistic regression analysis were entered into multivariate logistic regression analysis, and finally, variables with a P value <0.05 in multivariate logistic regression were considered significantly associated with the dependent variable. RESULTS: The total goiter rate was 43%, 95% CI = 39.2-46.9. Cassava consumption (AOR: 2.02, 95% CI: 1.03-4), salt wash before use (AOR: 3.14, 95% CI: 1.1-11.3), salt use after >2 months of purchase (AOR: 11, 95% CI: 5-26), family history of goiter (AOR: 4.6, 95% CI: 1.4-15.8), and poor knowledge of iodized salt (AOR: 2.7, 95% CI: 1.4-5.5) were significant factors associated with goiter. CONCLUSION: Iodine deficiency was found to be severe in women of reproductive age in the study area. This showed that women of reproductive age, especially during pregnancy, are exposed to iodine deficiency and its adverse effects at delivery. Thus, they need urgent supplementation with iodine, improved access to foods rich in iodine, and intake of iodized salt. Additionally, health education should focus on the importance of iodized salt, the proper method of use, and the prevention of iodine deficiency, which are highly recommended to minimize the problem.

Minimum Dietary Diversity and Associated Factors among Lactating Mothers in Ataye District, North Shoa Zone, Central Ethiopia: A Community-Based Cross-Sectional Study.

BACKGROUND: Low dietary diversity superimposed with poor-quality monotonous diets is a major problem that often results in undernutrition, mainly micronutrient deficiencies. However, there is limited evidence on minimum dietary diversity and associated factors among lactating mothers in resource-poor settings, including the study area. Therefore, the objective of the study is to assess the prevalence of minimum dietary diversity and associated factors among lactating mothers in Ataye District, Ethiopia. METHODS: A community-based cross-sectional study design was used among 652 lactating mothers aged 15-49 years from January 25 to April 30, 2018. Dietary diversity was measured by the minimum dietary diversity indicator for women (MDD-W) using the 24-hour dietary recall method. Data were entered into EpiData version 4.2.0.0 and exported to the statistical package for social science (SPSS) version 24 for analysis using the logistic regression model. RESULTS: The prevalence of minimum dietary diversity among lactating mothers was 48.8% (95% CI: (44.7%, 52.9%). Having formal education ((AOR = 2.16, 95% CL: (1.14, 4.09)), a final say on household purchases ((AOR = 5.39, 95% CI: (2.34, 12.42)), home gardening practices ((AOR = 2.67, 95% CI: (1.49, 4.81)), a history of illness ((AOR = 0.47, 95% CI: (0.26, 0.85)), good knowledge of nutrition ((AOR = 5.11, 95% CI: (2.68, 9.78)), being from food-secure households ((AOR = 2.96, 95% CI: (1.45, 6.07)), and medium ((AOR = 5.94, 95% CI: (2.82, 12.87)) and rich wealth indices ((AOR = 3.55, 95% CI: (1.76, 7.13)) were significantly associated with minimum dietary diversity. CONCLUSION: The prevalence of minimum dietary diversity among lactating mothers was low in the study area. It was significantly associated with mothers having a formal education, final say on the household purchase, home garden, good knowledge of nutrition, history of illness, food-secure households, and belonging to medium and rich household wealth indices. Therefore, efforts should be made to improve the mother's decision-making autonomy, nutrition knowledge, household food security, and wealth status.

Food insecurity and its predictors among lactating mothers in North Shoa Zone, Central Ethiopia: a community based cross-sectional study.

OBJECTIVE: To assess the prevalence of food insecurity (FI) and its predictors among lactating mothers in Ataye District, North Shoa Zone, Central Ethiopia. DESIGN: A community-based cross-sectional study design was used. SETTING: Two urban and four rural randomly selected kebeles of the Ataye District in Ethiopia. PARTICIPANTS: Out of 635 participants, 612 lactating mothers aged 15-49 years participated from February to April 2018. Mothers who lived for at least 6 months and above in the district were included, and mothers who were not able to respond to an interview were excluded. A single lactating mother per household was included. Lactating mothers in the households were selected using a cluster sampling technique. The number of lactating mothers found in each kebele was taken from family folder documentation. PRIMARY OUTCOME: The prevalence and predictors of food insecurity. RESULTS: The prevalence of FI among lactating mothers was 36.8%. No formal education (adjusted OR (AOR) =1.82, 95% CI 1.13 to 2.92), no income-generating activities (AOR=3.39, 95% CI 2.05 to 5.64), no home gardening practice (AOR=5.65, 95% CI 3.51 to 9.08), alcohol use by husbands (AOR=2.02, 95% CI 1.25 to 3.24), low minimum dietary diversity score (AOR=2.94, 95% CI 1.88 to 4.57), less than three frequencies of meals (AOR=3.97, 95% CI 1.65 to 9.54) and three meals only per day (AOR=1.86, 95% CI 1.08 to 3.17) were significant predictors of FI of mothers. CONCLUSION: The prevalence of FI was high in the study area. No formal education, no income-generating activities, no home gardening practice, alcohol use by husbands, low minimum dietary diversity score, fewer than three frequencies of meals and three meals only per day were independent predictors of FI. Therefore, increasing home gardening, decreasing alcohol intake, increasing dietary diversity and performing income-generating activities are highly recommended to reduce FI.

Prevalence of Anemia and Associated Factors among Infants and Young Children Aged 6-23 Months in Debre Berhan Town, North Shewa, Ethiopia.

BACKGROUND: Anemia is a problem of both the developed and developing world, which occurs in all age groups of the population. Half of the anemia cases are due to iron deficiency and affects physical growth and mental development. Nevertheless, there is a scarcity of information about anemia and associated factors among infants and young children aged 6 to 23 months in low-income countries like Ethiopia. OBJECTIVE: The aim of this study was to assess the prevalence of anemia and associated factors among infants and young children aged 6-23 months. METHODS: A community-based cross-sectional study design was used among 531 mothers/caregivers-children pairs in Debre Berhan Town, North Shewa, Ethiopia, from February 1 to March 2, 2018. The cluster sampling technique was used to select the study participants. Sociodemographic data were collected from mothers/caregivers using pretested structured questionnaires. Hemoglobin levels were measured using a HemoCue analyzer machine (HemoCue® Hb 301, Ängelholm, Sweden). All relevant data were described using descriptive statistics such as frequencies, proportions, mean, and standard deviation. Odds ratio and 95% CI were estimated using binary logistic regression to measure the strength of the association between anemia and explanatory variables. The level of statistical significance was declared at P < 0.05. RESULTS: The overall prevalence of anemia was 47.5% (95% CI: 43.1-51.4%) of which 18.3% were mildly anemic, 25% were moderately anemic, and 4.1% were severely anemic. In multivariable logistic regression analysis, household food insecurity (AOR = 2.7, 95% CI: 1.6-4.5), unmet minimum dietary diversity (AOR = 2.5, 95% CI: 1.4-4.3), stunting (AOR = 2.3, 95% CI: 1.2-4.3), and underweight (AOR = 2.7, 95% CI: 1.4-5.4) positively associated with anemia while having ≥4 antenatal care visits (AOR = 0.5, 95% CI: 0.3-0.9) and met minimum meal frequency (AOR = 0.25, 95% CI: 0.14-0.45) had a protective effect against anemia. CONCLUSION: Generally, the study showed that anemia was a severe public health problem among infants and young children in the study setting. Antenatal care visit, meal frequency, dietary diversity, underweight, stunting, and food insecurity significantly associated with anemia. Therefore, efforts should be made to strengthen infant and young child feeding practices and antenatal care utilization and ensure household food security, thereby improving the nutritional status of children.