[Monostotic fibrous dysplasia. Three cases and literature review]. / Displasia fibrosa monostótica. A propósito de tres casos y revisión de la literatura.

The fibrous dysplagia is a rare benign osseous pathology of unknown aetiology. It presents an incidence of craniofacial affectation of a 10% in its monostotic variety and a 100% in the poliostotic. The temporal bone implication is very rare, being usually referred in the monostotic variety. The diagnosis is based on radiology (CT) and histology. The majority of the authors agree in a conservative treatment. We present three clinical cases of monostotic fibrous dysplagia with craniofacial affectation, two of them in the temporal bone and another one in the frontal bone.

[ORL manifestations of myasthenia gravis]. / Manifestaciones ORL de la miastenia gravis.

Myasthenia gravis is an illness of insidious onset whose first manifestation often is dysphagia. We report the case of a 25 year-old woman who consulted for nosebleed. On her first visit she referred progressive dysphagia, but the results of endoscopic digestive examination and indirect laryngoscopy were normal. The condition evolved until the appearance of weakness of the extremities suggested myasthenia. Myasthenia gravis was diagnosed by means of electromyography and determinations of antibodies against acetylcholine receptors. We reviewed the literature on the clinical manifestations, diagnostic procedures, and treatment of this condition. This case highlights the importance of suspecting myasthenia gravis in young women with dysphagia and a family or personal history of autoimmune disease in order to reach an early diagnosis and treatment.

[Paraneoplastic syndrome as a manifestation of cancer of the hypopharynx]. / El síndrome paraneoplásico como manifestación de un cáncer de hipofaringe.

A 45-year-old male patient had a squamous-cell carcinoma of the laryngopharynx (T1pN2bM0). The first clinical manifestation was polyarthritis of large and small joints and a skin rash. The symptoms were identified as paraneoplastic syndrome associated with squamous-cell carcinoma of the laryngopharynx. After treatment (surgery + radiotherapy), the articular symptoms, initially treated with conventional therapy for rheumatoid arthritis, disappeared. Paraneoplastic syndrome can be defined as a set of physiological signs and symptoms of malignant origin that occur remote from the tumor. Squamous-cell carcinoma is the most frequent malignant tumor of the head and neck that produces paraneoplastic syndrome. We reviewed the most common features associated with malignant tumors and the pathogenic mechanisms involved. We conclude that paraneoplastic disorders can be markers of treatment response and predictors of recurrence.

[Oncocytoma of submaxillary gland]. / Oncocitoma de glándula submaxilar.

Oncocytoma of the salivary submaxillary gland is a well-known growth, but more frequently sitting on the parotid gland. Benign tumor which histological features are well-defined, but needing a thoroughly anatomo-pathological study in order to attaint a correct diagnosis. The AA. report one case of submaxillary oncocytoma and comment about its clinical, histological and therapeutical peculiarities.

[Peripheral centrofacial T lymphoma]. / Linfoma T periférico centrofacial.

Differentiating between Wegener's granulomatosis and other destructive centrofacial lesions often is difficult for clinicians and pathologists. It has become more confusing since what until now was known as "malignant centrofacial granulomatosis" seems to be a peripheral T-cell lymphoma. The case of an 83-year-old male recently diagnosed as angiocentric peripheral T-cell lymphoma which presented as a destructive centrofacial process is reported. The probable pathogenic role of Epstein-Barr virus (EBV) is highlighted.

[An immunohistochemical study of chronic otitis media]. / Estudio inmunohistoquímico de las otitis medias crónicas.

We use immunohistochemical procedures (OKT6) to detect LCs. We have studied tissue samples from surgical operations in cases of chronic otitis media. The samples were from skin of external ear canal, both the superior wall (close to cholesteatoma) and the inferior wall; we took also samples from the cholesteatoma matrix (epidermal and subepidermal stratum). We found LCs in the skin of external ear canal in similar proportion if the samples were of superior or inferior wall. In cholesteatoma tissue (17 cases) we observed LCs in the epidermal stratum in greater proportion than in skin. Sometimes the LCs form aggregates or "clusters".

[Tumors of the jugular and tympanic glomus. Unusual locations. Magnetic resonance imaging in the diagnosis. Comments on 3 cases]. / Tumores del glomus timpanicum y yugularis. Localizaciones poco frecuentes. La RNM en el diagnostico. Comentario de tres casos.

Inform about the last contributions to the subject published. The importance of the N.M.R. and its place respect to the T.A.C. is considered. Report of cases localized and behaving atypically lately published are reviewed. Other 3 cases diversely localized in the glomus system tympano-jugularis, as well as its diagnosis, treatment and evolution are included. Only those cases spreading to the endocranium are excluded.