1.
Nat Prod Bioprospect
; 14(1): 37, 2024 Jun 11.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38861197
RESUMEN
Cyclobutanes are distributed widely in a large class of natural products featuring diverse pharmaceutical activities and intricate structural frameworks. The [2 + 2] cycloaddition is unequivocally the primary and most commonly used method for synthesizing cyclobutanes. In this review, we have summarized the application of the [2 + 2] cycloaddition with different reaction mechanisms in the chemical synthesis of selected cyclobutane-containing natural products over the past decade.