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Pol Merkur Lekarski ; 52(1): 5-9, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38518226

RESUMEN

OBJECTIVE: Aim: To analyse onconeural antibodies in the blood serum of breast cancer patients without neurological symptoms.. PATIENTS AND METHODS: Materials and Methods: The study included 48 women with breast cancer. Paraneoplastic Neurologic Syndromes 12 Ag (IgG) Euroline by EUROIMMUN test was used to determine onconeural antibodies: anti-Hu, anti-Yo, anti-Ri, anti-CV2, anti-Ma/anti-Ta, anti-amphiphysin, anti-recoverin, anti-SOX1, anti-tytin, anti-zic4, anti-GAD65 and anti-Tr (DNER). RESULTS: Results: The conducted analysis revealed the presence of onconeural antibodies such as: anti-recoverin, anti-CV2, anti-Zic4, anti-SOX1, anti-MA2/Ta and antititin in blood serum of women with breast cancer. CONCLUSION: Conclusions: Further analysis may allow the assessment of the possible clinical usefulness of these determinations.


Asunto(s)
Neoplasias de la Mama , Síndromes Paraneoplásicos del Sistema Nervioso , Humanos , Femenino , Prevalencia , Síndromes Paraneoplásicos del Sistema Nervioso/diagnóstico , Autoanticuerpos
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