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1.
Intern Med ; 2024 Aug 08.
Artículo en Inglés | MEDLINE | ID: mdl-39111887

RESUMEN

We herein report a case of Takotsubo syndrome in an 80-year-old woman with end-stage renal disease who hesitated to initiate hemodialysis for pulmonary edema. On hospital day 2, the patient experienced cardiac arrest. Coronary angiography after spontaneous return of circulation showed no substantial stenosis. Takotsubo syndrome was diagnosed based on echocardiography findings. On hospital day 3, she developed ventricular fibrillation but was spontaneously resuscitated. Patients with chronic kidney disease and those who postpone dialysis initiation may be at an increased risk of developing Takotsubo syndrome. Early and careful monitoring and adequate shared decision-making are essential for seamless initiation of dialysis.

2.
Intern Med ; 63(5): 707-710, 2024 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-37438136

RESUMEN

A 60-year-old man with end-stage renal disease due to nephrosclerosis had a peritoneal dialysis catheter (PD) embedded with stepwise initiation of peritoneal dialysis using Moncrief and Popovich's technique three months ago. PD was initiated three weeks after creating an exit site. He presented with abdominal pain and fever a day before admission and was diagnosed with PD-associated peritonitis caused by Streptococcus oralis. Medical consultation after admission revealed a history of wisdom tooth extraction following PD catheter placement, resulting in delayed wound healing. Transient bacteremia can occur after tooth extraction, leading to PD-associated peritonitis. Contemplating the oral milieu in patients undergoing PD is pertinent.


Asunto(s)
Fallo Renal Crónico , Diálisis Peritoneal , Peritonitis , Masculino , Humanos , Persona de Mediana Edad , Streptococcus oralis , Diálisis Peritoneal/efectos adversos , Peritonitis/etiología , Peritonitis/diagnóstico , Fallo Renal Crónico/terapia , Fallo Renal Crónico/complicaciones
3.
Org Lett ; 23(6): 2380-2385, 2021 Mar 19.
Artículo en Inglés | MEDLINE | ID: mdl-33703908

RESUMEN

Herein we report an efficient synthetic method for the electrophilic trifluoromethylthiolation of aromatic compounds. The key is to use triptycenyl sulfide (Trip-SMe) and TfOH to enhance the electrophilicity of SCF3 fragment through the formation of sulfonium intermediates. This method enables direct installation of an SCF3 group onto unactivated aromatics at room temperature, adopting a commercially available saccharin-based reagent. Preliminary DFT calculation was carried out to investigate the substitution effect on the catalytic activity.

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