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Pak J Pharm Sci ; 34(4): 1397-1401, 2021 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-34799313

RESUMEN

The current research was aimed to isolate newer phyto-metabolites from rhizomes of Alpinia galanga plant. Study involved preparation of Alpinia galanga rhizome methanolic extract, followed by normal phase column chromatography assisted isolation of new phytometabolites (using different combinations of chloroform and methanol), and characterization (by UV, FTIR, 13C-NMR, 1H-NMR, COSY, DEPT and Mass spectrometry). The isolation and characterization experiment offered two phytometabolites: an ester (Ag-1) and tetrahydronapthalene type lactone (Ag-2). Present study concludes and reports the two phytometabolites, benzyl myristate (Ag-1) and 3-Methyl-6α, 8ß-diol-7-carboxylic acid tetralin-11, 9ß-olide (Ag-2) for the first time in Alpinia galanga rhizome. The study recommends that these phytometabolites Ag-1 and Ag-2 can be utilized as effective analytical biomarkers for identification, purity and quality control of this plant in future.


Asunto(s)
Alpinia/química , Extractos Vegetales/aislamiento & purificación , Rizoma/química , Compuestos de Bencilo/química , Compuestos de Bencilo/aislamiento & purificación , Espectroscopía de Resonancia Magnética , Estructura Molecular , Miristatos/química , Miristatos/aislamiento & purificación , Fitoquímicos/química , Fitoquímicos/aislamiento & purificación , Extractos Vegetales/química
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