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Psychiatr Danub ; 29 Suppl 4(Suppl 4): 823-829, 2017 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-29278630

RESUMEN

The aims of this study were to compare predictive values of hsTroponin I assay with contemporary assays and its usefulness in diagnosis of acute coronary syndrome (ACS). We also aimed to determine reference values of the assay and the possibility of fast ACS diagnosis using hsTnI. The study included 26 patients with ongoing chest pains and suspected ACS. ACS diagnosis was determined using electrocardiographic changes and international guidelines. Biochemical parameters were measured using standard tests which included Troponin I, hsTroponin I, CK, CK-MB and CRP. 10 (38.5 %) patients out of 26 were diagnosed with ACS. Median age was 63.92 years. Comparison of predictive values showed that hsTnI and TnI had an advantage before CK, CK-MB and CRP. hsTnI showed no significant improvements over TnI. With an perfect negative predictive value at admission, hsTnI is recommended for use as a rule-out method for ACS in patients with chest pain and suspected ACS on admission. hsTnI was superior to contemporary TnI assays only as a rule-out method for suspected ACS patients at admission.


Asunto(s)
Síndrome Coronario Agudo/diagnóstico , Troponina I/sangre , Síndrome Coronario Agudo/sangre , Anciano , Biomarcadores/sangre , Femenino , Hospitalización , Humanos , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Pronóstico , Sensibilidad y Especificidad
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