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J Clin Nurs ; 33(10): 4112-4123, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-38797947

RESUMEN

AIMS: Establishing a nomogram to estimate the probability of oral mucosal membrane pressure injury of endotracheal tube-intubated hospitalized patients in intensive care unit. DESIGN: Multicentre prospective cohort study. METHODS: Using Lasso regression and COX regression, variable selection was performed on demographic, clinical and laboratory data of 1037 ICU endotracheal tube-intubated hospitalized patients from West China Hospital, to construct a nomogram. External validation was conducted on 484 ICU endotracheal tube-intubated patients from People's Hospital of Zhongjiang County. RESULTS: Among 38 potential predictors, five variables emerged as independent predictors, integrated into the nomogram: administration of antibiotics, nutritional therapy duration, agitation, hypotension and albumin levels. CONCLUSIONS: We established a nomogram based on the hospital characteristics of ICU endotracheal tube-intubated patients, aiding in the prediction of the occurrence of oral mucosal membrane pressure injury. REPORTING METHOD: The study followed TRIPOD guidelines. RELEVANCE TO CLINICAL PRACTICE: The nomogram we developed can assist clinical worker in better identifying at-risk patients and risk factors. It enables the implementation of evidence-based nursing interventions in care to prevent the development of oral mucosal membrane pressure injury. TRIAL REGISTRATION: The study has been registered with the Chinese Clinical Trial Registry (http://www.chictr.org.cn) under registration number ChiCTR2200056615.


Asunto(s)
Intubación Intratraqueal , Mucosa Bucal , Nomogramas , Úlcera por Presión , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , China , Estudios de Cohortes , Unidades de Cuidados Intensivos , Intubación Intratraqueal/efectos adversos , Intubación Intratraqueal/instrumentación , Mucosa Bucal/lesiones , Úlcera por Presión/epidemiología , Úlcera por Presión/fisiopatología , Úlcera por Presión/prevención & control , Estudios Prospectivos , Factores de Riesgo
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