Wheat Pm55 alleles exhibit distinct interactions with an inhibitor to cause different powdery mildew resistance.

Powdery mildew poses a significant threat to wheat crops worldwide, emphasizing the need for durable disease control strategies. The wheat-Dasypyrum villosum T5AL·5 V#4 S and T5DL·5 V#4 S translocation lines carrying powdery mildew resistant gene Pm55 shows developmental-stage and tissue-specific resistance, whereas T5DL·5 V#5 S line carrying Pm5V confers resistance at all stages. Here, we clone Pm55 and Pm5V, and reveal that they are allelic and renamed as Pm55a and Pm55b, respectively. The two Pm55 alleles encode coiled-coil, nucleotide-binding site-leucine-rich repeat (CNL) proteins, conferring broad-spectrum resistance to powdery mildew. However, they interact differently with a linked inhibitor gene, SuPm55 to cause different resistance to wheat powdery mildew. Notably, Pm55 and SuPm55 encode unrelated CNL proteins, and the inactivation of SuPm55 significantly reduces plant fitness. Combining SuPm55/Pm55a and Pm55b in wheat does not result in allele suppression or yield penalty. Our results provide not only insights into the suppression of resistance in wheat, but also a strategy for breeding durable resistance.

Body image construction and mental health levels among college students: a data survey of Chinese university students.

Background: With the rapid changes in body image construction brought about by the upgrading of consumption in China, trend-seeking college students are faced with mental health problems brought about by the pursuit of the "ideal body type," which cannot be ignored. This study aims to explore the relationship between body image construction and mental health among college students. This study utilized data from the Survey on Physical Activity and Mental Health of College Students. A total of 1,192 students were randomly selected as the survey sample, and 1,044 valid samples were obtained. The mean age of the respondents was 19.34 years. Methods: First, we categorized body image constructs into three categories based on the differences between subjective and objective body image: high acceptance, low acceptance, and consistency. Second, to ensure analytical rigor and minimize potential confounders, we used a generalized propensity score weighting model. Finally, we used a causal mediation framework to investigate the potential causal mechanisms between the independent variable (perceived body image bias) and the dependent variable (mental health) in order to better understand the "net effect." Results: (1) There is a significant correlation between college students' body image perceptual bias and mental health, i.e., the higher the individual's acceptance of his/her own body image, the higher the level of mental health, and vice versa. (2) Students in humanities and social sciences are more likely to have increased psychological burden due to poor negative body image. (3) In the mediation analysis, although the causal mediating effect of physical exercise was not significant, family and peer support in physical exercise played an important mediating role, especially the influence of peers was more significant. Conclusion: The construction of body image is a double-edged sword that can either promote positive individual development or lead to self-depreciation. Creating a positive climate for physical activity has a positive impact on college students' mental health compared to participation in physical activity behaviors. While improving students' media literacy on college campuses, it is important to enhance adaptive guidance to promote their physical and mental health and personal development.

The influence of environmental awareness and conditions on successful aging: Evidence of air and water pollution in China.

This study examines three aspects of successful aging including subjective health, cognitive ability, and social participation and their relations with environmental conditions and environmental awareness. We used the seemingly uncorrelated regression and multilevel models to estimate the joint relationship by combining the Chinese General Social Survey (2013 and 2021) (N = 5404 and 1580 accordingly) and the Chinese Statistical Yearbook and used propensity score analysis to identify potential endogenous issues. The first finding is that older people who were men, married, lived in urban areas, or received social security had an edge in aging successfully. Secondly, the adverse effects of environmental pollution on older adults' cognitive ability and social participation can be reduced by the protective effects of environmental awareness. Additionally, air pollution had more apparent effects, and water pollution was more modest in social involvement. This study offers empirical results to enhance the well-being of the older population by lifting their environmental perception and improving environmental quality.

Air Quality, Pollution Perception, and Residents' Health: Evidence from China.

Environmental and resident health issues associated with air pollution are an area of growing concern for both policy officials and the general public. In recent years, China has been accelerating the construction of a Beautiful China and a Healthy China, with the aim of protecting and improving the environment and ensuring public health. In this study, we aimed to explore the impact of air quality and air pollution perception on residents' health. This study used the 2017 Chinese General Social Survey data to measure self-rated health, mental health, and air pollution perception. Using matched socioeconomic indicators and air pollution data, we analyzed the relationship between subjective perception of air pollution, objective air pollution data, and residents' health. The results showed the following: (1) Air pollution perception has a significant negative impact on self-rated health and mental health. Thus, it needs more consideration to reduce environmental health risks. (2) Objective air pollution has a significant negative impact on mental health. At the same time, its effect on self-rated health was insignificant. These results provide empirical evidence supporting the Chinese government's decision to invest more in combating air pollution and ensuring the health of Chinese residents.

Social Class and Private-Sphere Green Behavior in China: The Mediating Effects of Perceived Status and Environmental Concern.

Green behavior is traditionally considered as an effective way to ameliorate environmental degradation and requires an individual to make sacrifices of their social resources. However, few studies have focused on its status signaling. In this study, we draw on the theory of social class and the concept of status signaling theory to empirically investigate the effect of objective social class and perceived social status on private-sphere green behavior in China. Using national comprehensive survey data from China General Survey Data (CGSS) in 2021 subjected to ordinary least-square regression model and step regression models, we present the following results: (1) higher-class individuals, both objectively and subjectively, tend to engage in more private-sphere green behavior than their lower-class counterparts; (2) the effect of objective social class on private-sphere green behavior is mediated by individual's perceived social status in the class hierarchy; (3) environmental concern significantly correlates with private-sphere green behavior, and it also mediates the effect between objective social class and private-sphere green behavior. The present research provides insights into how social class and its psychological manifestations (i.e., perceptions of status) correlate with private-green behavior in China. Our results suggest that more social context factors should be considered when identifying the factors promoting pro-environmental behavior in China.

Physical Activity and Sleep Quality Association in Different Populations: A Meta-Analysis.

The meta-analysis statistical methodology was used to test the effect of physical activity intervention on sleep quality. According to the preliminary results of the meta-analysis, moderating variables (age stage and physical activity intensity) were included for further study. On this basis, measures and schemes to improve sleep quality through physical activity were put forward. A preliminary Endnote X9 search of relevant literature from six electronic databases (Web of Science, Medline, PubMed, CNKI, PsycINFO and Wanfang) was performed. The results showed the following: (1) The overall test effect of physical activity intervention on sleep quality was not significant (p = 0.15). (2) Moderate- and low-intensity physical activity had significant effects on sleep quality (moderate intensity d = 2.56, p = 0.015; low-intensity d = 1.38, p = 0.03), while high-intensity physical activity had no obvious effect on sleep quality (d = 1.12, p = 0.32). (3) There were differences in the effect of physical activity on sleep quality at different ages. The effect of physical activity on sleep quality was more obvious in children and middle-aged and elderly people (children d = 1.24, p = 0.03; middle-aged and elderly people d = 1.98, p = 0.037), but not in young people (d = 1.32, p = 0.11). Conclusion: The overall effect of physical activity on sleep quality was not significant. Physical activity had an obvious effect on the sleep quality of children and middle-aged and elderly people but had no obvious effect on young people. Moderate-intensity physical activity had a certain effect on sleep quality, but high-intensity physical activity had no obvious effect on sleep quality. Future studies need to confirm these findings with a good large sample and moderating variables.

Life cycle assessment of shared electric bicycle on greenhouse gas emissions in China.

Following the bike-sharing system, the shared electric bicycle (SEB) is experiencing explosive growth in China as an emerging shared transportation mode. While shared transportation has long been linked to energy conservation and reducing emissions, a major problem facing SEB is whether it can reach the goal of greenhouse gas (GHG) reduction. This paper aims to evaluate GHG emissions at each stage of production, operation, and disposal of the SEB using life cycle assessment of GHG emissions. We also compared the differences in GHG emissions between the recycling incineration scenario (H1) and the recycling degradation scenario (H2) in the disposal stage. The GHG emissions of SEB in the production and operation stages were found to be 379.6173 kg CO2-eq and 183.4663 kg CO2-eq, respectively. However, the GHG emission reduction in the use stage was 1049.8374 kg CO2-eq. Thus, the net GHG reduction in the life cycle of the SEB was 487.3923 kg CO2-eq. (H1) and 433.9215 kg CO2-eq. (H2), respectively, indicating that SEB had a green effect. Non-recyclable parts of SEB will take 48 years to degrade in landfills in the H2 scenario. The GHG emission thresholds for SEB were further discussed. When the average daily turnover rate of SEB was less than 4 and its operation day was less than 479, SEB would not be able to achieve the goal of GHG reduction in the whole life cycle, with the riding statistics remaining unchanged. Finally, some advice for practical issues of electric bicycle sharing in energy conservation and GHG reduction were presented in response to the results.

Is there a casual relation between air pollution and dementia?

Dementia has been cited as a critical public health risk in the contemporary world, while few empirical researchers try to reveal the casual relationship between air pollutant concentrations (APCs) and dementia, especially given the increasing prevalence of air pollution on a global scale. Accordingly, this paper tries to infer the causal relationship between APCs and dementia. The 59,605 valid data was compiled through a combination of the statistic from the China Family Panel Study, China Environmental Statistics Yearbook, World Meteorological Association and China National Bureau of Statistics. The RD design of this study utilizes the discontinuous variation in APCs and dementia as one crosses the Huai River boundary, which is an arbitrary heating policy that causes the significant difference in APCs between the north and south of China. We used stata17.0 to analyze the data. The results of the RD regression indicated that a 100 µ g/m3 rise in APCs led to an increase of 42.4% in the hazard ratio of suffering dementia (Coeff=-0.58, SD= 0.23, P < 0.05). Meanwhile, heterogeneous models revealed that the hazard ratio of suffering dementia by APCs was more significant in the older compared to younger (coeff= 1.35 vs coeff= 1.55, P < 0.05), male compared to female (coeff= 1.62 vs coeff= 0.71, P < 0.05), smoking compared to non-smoke (coeff= 2.12 vs coeff= 0.93, P < 0.05), and thin groups compared to medium and obesity (coeff= 2.05 vs coeff= 1.22, coeff= 1.28, P < 0.05). In addition, the O3 and SO2 were the air pollutants with the highest (coeff= 1.54, P < 0.05) and lowest effects (coeff= 0.81, P < 0.05) on the hazard ratio of suffering dementia among the five APCs, respectively. And the robustness of the results was ensured by changing the RD bandwidth, polynomial order. The results indicated that APCs significantly induced the hazard ratio of suffering dementia of Chinese residents, which provides empirical evidence in supporting the Chinese government to invest more in combating air pollution and ensure the public health of Chinese residents.

Mobile phone addiction and depressive symptoms among Chinese University students: The mediating role of sleep disturbances and the moderating role of gender.

Background: With the continuous updating of mobile phone functions, the phenomenon of mobile phone addiction among University students is becoming more and more serious. It is important to identify the potential risk factors for mobile phone addiction. The aim of the study was to examine whether there is a relationship between mobile phone addiction and depression symptoms in University students, and to investigate whether sleep disturbances play a mediating role between mobile phone addiction and depression symptoms, as well as the moderating role of gender. Methods: A cross-sectional study, carried out between September to December 2021, recruited 973 students (478 males) from seven comprehensive universities in western China. The Mobile Phone Addiction Index (MPAI), the Patient Health Questionnaire-9 (PHQ9), and the Pittsburgh Sleep Quality Index (PSQI) were used to complete measures of mobile phone addiction, depressive symptoms, and sleep disturbances. For statistical analyses, descriptive statistics, correlation, regression, mediation and moderated mediation analyses were used. Furthermore, we tested the mediation model and moderated mediation model using the SPSS macro PROCESS. Results: In this study, it was found that there were positive correlations between mobile phone addiction and depressive symptoms among Chinese University students. Mediation analyses revealed that this relationship was partially mediated by sleep disturbances, but the mediating role was not moderated by gender. Conclusion: Sleep disturbances have a partial mediating role in the relationship between mobile phone addiction and depressive symptoms. Our results highlight the critical role of prevention and early identification of mobile phone addiction among University students, especially those with sleep disturbances.

Screen time and myopia: A serial multiple mediator SEM analysis.

Background: COVID-19 has influenced education systems worldwide, and significantly increased screen time for college students, posing a potential risk of myopia. In China, ninety percent of college students suffer from myopia. Excessive screen time changes college students' lifestyles, imposes potential health risks, and affects opportunities for employment. It is important to identify the potential correlation between screen time use and myopia among college students. Methods: This paper conducted a nationwide experiment using Chinese college students and set a multiple-mediator SEM model to analyze the potential correlation between screen time and myopia. The two mediators were sedentary behavior and physical activity, respectively. Results: We obtained three valuable conclusions as follows: First, there was no significant direct relationship between screen time and myopia among Chinese college students during the COVID-19 pandemic. Second, sedentary behavior and physical activity significantly predicted the increase/decrease of myopia among Chinese college students, respectively. Third, a serial multiple mediator that encompassed sedentary behavior and physical activity sequentially fully mediated the relationship between screen time and myopia. Conclusions: Although there was no directly significant relationship between screen time and myopia, screen time can indirectly influence the risk of suffering myopia by influencing sedentary behavior and physical activity. Our study demonstrates the need to prevent the potential influence of overuse of electronic devices on myopia in college students, especially during the COVID-19 pandemic.

Fine mapping of powdery mildew and stripe rust resistance genes Pm5V/Yr5V transferred from Dasypyrum villosum into wheat without yield penalty.

KEY MESSAGE: The novel wheat powdery mildew and stripe rust resistance genes Pm5V/Yr5V are introgressed from Dasypyrum villosum and fine mapped to a narrowed region in 5VS, and their effects on yield-related traits were characterized. The powdery mildew and stripe rust seriously threaten wheat production worldwide. Dasypyrum villosum (2n = 2x = 14, VV), a relative of wheat, is a valuable resource of resistance genes for wheat improvement. Here, we describe a platform for rapid introgression of the resistance genes from D. villosum into the wheat D genome. A complete set of new wheat-D. villosum V (D) disomic substitution lines and 11 D/V Robertsonian translocation lines are developed and characterized by molecular cytogenetic method. A new T5DL·5V#5S line NAU1908 shows resistance to both powdery mildew and stripe rust, and the resistances associated with 5VS are confirmed to be conferred by seedling resistance gene Pm5V and adult-plant resistance gene Yr5V, respectively. We flow-sort chromosome arm 5VS and sequence it using the Illumina NovaSeq 6000 system that allows us to generate 5VS-specific markers for genetic mapping of Pm5V/Yr5V. Fine mapping shows that Pm5V and Yr5V are closely linked and the location is narrowed to an approximately 0.9 Mb region referencing the sequence of Chinese Spring 5DS. In this region, a NLR gene in scaffold 24,874 of 5VS orthologous to TraesCS5D02G044300 is the most likely candidate gene for Pm5V. Soft- and hard-grained T5DL·5V#5S introgressions confer resistance to both powdery mildew and stripe rust in diverse wheat genetic backgrounds without yield penalty. Meanwhile, significant decrease in plant height and increase in yield were observed in NIL-5DL·5V#5S compared with that in NIL-5DL·5DS. These results indicate that Pm5V/Yr5V lines might have the potential value to facilitate wheat breeding for disease resistance.

The Influence of Dementia Beliefs and Knowledge on Perceived Dementia Worry: An Empirical Study Among Adults in Rural China.

Alzheimer's disease and related dementias are more prevalent in rural areas than in urban areas in China. This study aims to examine the role of dementia beliefs and knowledge in influencing dementia worry among rural adults in China. Data were generated in a cross-sectional survey of 577 participants. Hierarchical regression analyses found that both the beliefs and knowledge of dementia contributed to higher levels of dementia worry. The propensity score matching method affirmed the robustness of regression results. In addition, those aged 45-64 reported higher worry about dementia than those aged 65 or older, while being married was related to lower dementia worry. As one of the first kind studies that examined dementia worry in rural Chinese population, our findings suggest that policy and practice efforts should address cultural beliefs of dementia as they contributed to higher worry about dementia in rural areas.

Relations among Pro-Environmental Behavior, Environmental Knowledge, Environmental Perception, and Post-Materialistic Values in China.

During the economic boom, China's government was mainly concerned with economic development; however, numerous environmental problems have arisen. Evidence suggests that Chinese individuals' pro-environmental behavior (PEB) is at a low level in Asia. However, it does not match their high-quality environmental knowledge. In this paper, the database of the Chinese General Social Survey was used to explore the correlation between environmental knowledge and PEB in a broader context. Subsequently, environmental perception and post-materialistic values (PMV) were taken as the mediator and moderator into structural equation modeling, and every variable kept robust and consistent through exploratory factor analysis. The empirical results indicated that: (i) individuals with higher environmental knowledge always show higher passion to PEB; (ii) environmental perception plays a partially mediating role between environmental knowledge and PEB; (iii) PMV moderate the formation of environmental behavior systematically; and (iv) compared with public counterpart, the relation between environmental knowledge and PEB is significantly higher in private environmental behavior. The study results could become the basis for the Chinese government and environmental NGOs to effectively spread environmental knowledge, advocate a post-materialistic lifestyle, and improve the authenticity of online media reports on environmental issues.

Causal effects and functional mechanisms of the Internet on residents' physical fitness-An empirical analysis based on China family panel survey.

Introduction: Physical fitness is an essential part of a healthy lifestyle that concerns the overall health of the nation. Research on the relationship between the Internet and physical fitness has long been caught in the dilemma of "media mobilization" and "media suppression," and previous studies have rarely examined the causal relationship and functional mechanism. Methods: This study selected the data of 23,989 samples successfully followed in all three surveys of the China Family Panel Survey (CFPS) from 2014 to 2018 to explore the correlation and causal inference between the Internet and physical fitness by using the Time Fixed Effects Model and cross-lagged models, respectively; meanwhile, the data of 24,687 samples in CFPS 2020 to examine the functional mechanism of the Internet's effect on residents' physical fitness behavior by the KHB method. Results: We obtained three valuable conclusions as follows: First, there is a significant correlation between the Internet and physical fitness behavior. Second, the Internet use is the cause for the increase in fitness frequency, and there is a rival relationship between Internet duration and fitness time. Third, under regular prevention and control of the COVID-19 epidemic, social capital and health risk perceptions are the functional mechanisms of the Internet influencing fitness behavior, and the mediating effect of psychological health risk perceptions is higher than that of social capital. Discussion: It's necessary to create an intelligent, informative, and digital sports public service system by enriching and optimizing sports media and facilitating the Internet to serve residents' physical fitness better. The new concept of "Internet plus Fitness" will be of great significance in the implementation of the "Healthy China Initiative."

COVID-19, a critical juncture in China's wildlife protection?

The COVID-19 crisis has called into question the utilitarianism-oriented human-wildlife relations and the legitimacy of wildlife protection regime in China. The pandemic has triggered significant, swift, and encompassing changes in policies. Drawing on insights from historical institutionalism, we argue that COVID-19 constitutes a critical juncture in China's wildlife protection policy.

Risk factors for completed suicide in the general population: A prospective cohort study of 242, 952 people.

BACKGROUND: The estimated global burden of suicide is almost 1 million deaths per year, representing 57% of all violent deaths worldwide. In order to better identify at risk individuals and develop effective prevention strategies at the population level, a comprehensive understanding of the biological, psychological and social risk factors is required. METHOD: Data from the National Health Interview Survey (1997- 2004) were analyzed. Multivariable Cox proportional hazards regression models were used to compute hazard ratios (HRs) and accompanying 95% confidence intervals (CI). RESULTS: During a mean 6.3 years of follow-up of 242, 952 people (1.56 million person-years), 180 deaths due to suicide occurred. Of 18 risk factors, eight revealed associations with suicide. Participants who had never been married (HR, 2.58; 95% CI, 1.44-4.62), current smokers (HR, 2.26; 1.49-3.43), current drinkers (HR, 1.93; 1.14-3.27]), participants with serious psychological distress (HR, 3.34; 1.81-6.18), and a history of emphysema (HR, 2.79; 1.18-6.59), liver disease (HR, 4.63; 2.10-10.20), kidney disease (HR, 2.26; 1.00-5.06) and cancer (HR, 2.18; 1.32-3.59) were at increased risk of completed suicide. LIMITATIONS: Due to the observational nature of this study, we cannot exclude the possibility of reverse or bi-directional causality. CONCLUSIONS: This large, prospective cohort study identified a series of biopsychosocial risk factors that may have utility in suicide prevention.

The association between sleep duration and chronic diseases: a population-based cross-sectional study.

OBJECTIVES: To examine the cross-sectional relationship between sleep duration and 11 chronic diseases (risk of obesity, depression, diabetes, asthma, COPD, arthritis, kidney, CHD, stroke, and cancer [excluding skin cancer]) by using data from Behavioral Risk Factor Surveillance System. METHODS: Using data from the 2013, 2014 and 2016 Behavioral Risk Factor Surveillance System, a total sample consisted of 1,191,768 participants. Logistic regression models were constructed to calculate OR and 95% confidence intervals (CI) for the association between sleep duration and 11 chronic diseases. In addition, we also conducted subgroup analysis based on age and gender. RESULTS: In multi-adjusted model, the positive association between extremely short or long sleep duration and risk of chronic diseases was significant (P < 0.05) with the exception of skin cancer (P = 0.14 and P = 0.43). There are stronger association between extremely short or long sleep duration and obesity, diabetes, asthma, chronic obstructive pulmonary disease, arthritis, kidney, coronary heart disease, stroke, and cancer in women and aged 18-64 years old. CONCLUSIONS: Our results indicated a higher risk of common chronic diseases due to short or long sleep duration in women and aged 18-64 years. Further studies are needed to demonstrate these association.

How perceived exposure to environmental harm influences environmental behavior in urban China.

Rapid environmental degradation in China makes understanding how perceived exposure to environmental harm influences environmental attitudes and participation in pro-environmental behaviors among the Chinese people crucial. We used a nation-wide survey dataset in urban China to test two hypotheses: experiencing environmental harm directly affects environmental behavior; environmental attitudes mediate the relationship between experiencing environmental harm and environmental behavior. We found respondents who experienced environmental harm had more pro-environmental attitudes. Experiencing environmental harm positively influenced pro-environmental behavior both directly and indirectly through the mediation of pro-environmental attitudes. Among the pro-environmental behaviors, environmental litigation was most strongly related with exposure to environmental harm. Our results suggest that more participation in pro-environmental behaviors may be expected as rapid economic development increases public exposure to environmental harm in urban China.