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1.
J Parasitol ; 102(5): 559-561, 2016 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-27045334

RESUMEN

We tested whether the probability of detecting avian haemosporidia (Plasmodium and Haemoproteus) using molecular techniques differs among blood, liver, heart, and pectoral muscle tissues. We used a paired design, sampling the 4 tissue types in 55 individuals of a wild South American suboscine antbird, the white-shouldered fire-eye (Pyriglena leucoptera). We also identified parasites to cytochrome b lineage. Detection probability was significantly lower in blood compared to the other 3 tissue types combined. Eight of 22 infections were not detected in blood samples; 4-7 infections were not detected in the other individual tissues. The same parasite lineage was recovered from different tissues.


Asunto(s)
Haemosporida/aislamiento & purificación , Malaria Aviar/parasitología , Passeriformes/parasitología , Animales , Brasil , Citocromos b/genética , ADN Mitocondrial/química , ADN Mitocondrial/aislamiento & purificación , ADN Protozoario/química , ADN Protozoario/aislamiento & purificación , Corazón/parasitología , Hígado/parasitología , Malaria Aviar/sangre , Passeriformes/sangre , Músculos Pectorales/parasitología , Plasmodium/aislamiento & purificación
3.
Bioorg Med Chem Lett ; 14(6): 1573-5, 2004 Mar 22.
Artículo en Inglés | MEDLINE | ID: mdl-15006406

RESUMEN

We described in this paper the first synthesis to the (+/-) cis (6-ethyl-tetrahydropyran-2-yl) formic acid (1) using the very efficient Prins cyclization reaction as strategy to construction of its tetrahydropyran skeleton. This new compound presented a significant antinociceptive property by the tail-flick model.


Asunto(s)
Analgésicos/química , Analgésicos/farmacología , Formiatos/química , Formiatos/farmacología , Dimensión del Dolor/efectos de los fármacos , Animales , Ratones , Dimensión del Dolor/métodos
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