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Microb Pathog ; 190: 106639, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38616002

RESUMEN

BACKGROUND INFORMATION: The advancement of biological-mediated nanoscience towards higher levels and novel benchmarks is readily apparent, owing to the use of non-toxic synthesis processes and the incorporation of various additional benefits. This study aimed to synthesize stable tin oxide nanoparticles (SnO2-NPs) using S. rhizophila as a mediator. METHODS: The nanoparticles that were created by biosynthesis was examined using several analytical techniques, including Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM), X-ray diffraction (XRD), UV-visible (UV-vis) spectroscopy, and energy dispersive X-ray spectroscopy (EDS). RESULTS: The results obtained from the characterization techniques suggest that S. rhizophila effectively catalyzed the reduction of SnCl2 to SnO2-NPs duration of 90 min at ambient temperature with the ƛmax of 328 nm. The size of the nano crystallite formations was measured to be 23 nm. The present study investigates nanoscale applications' antibacterial efficacy against four bacterial strains, including Klebsiella Sp, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. The observed zone of inhibition for the nanoparticles (NPs) varied from 10 to 25 mm. The research findings demonstrate that the nanoparticles (NPs) are effective as antibacterial, phytotoxic, and cytotoxic agents.


Asunto(s)
Antibacterianos , Biopelículas , Pruebas de Sensibilidad Microbiana , Compuestos de Estaño , Difracción de Rayos X , Compuestos de Estaño/química , Compuestos de Estaño/farmacología , Biopelículas/efectos de los fármacos , Antibacterianos/farmacología , Antibacterianos/química , Animales , Staphylococcus aureus/efectos de los fármacos , Nanopartículas/química , Bacterias/efectos de los fármacos , Nanopartículas del Metal/química , Nanopartículas del Metal/toxicidad , Escherichia coli/efectos de los fármacos , Pseudomonas aeruginosa/efectos de los fármacos , Microscopía Electrónica de Transmisión , Microscopía Electrónica de Rastreo , Tamaño de la Partícula
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