RESUMEN
It is critical to monitor the structural evolution of complex fluids for optimal manufacturing performance, including textile spinning. However, in situ measurements in a textile-spinning process suffer from the paucity of non-destructive instruments and interpretations of the measured data. In this work, kinetic and rheo-optic properties of a cellulose/ionic liquid solution are measured simultaneously while fibers are regenerated in aqueous media from a model wet-spinning process via a customized polarized microscope. This system enables to capture key geometrical and structural information of the fiber under spinning at varying draw ratios and residence time, including the flow kinematics extracted from feature tracking, and the flow-induced morphology and birefringent responses. A physics-oriented rheological model is applied to connect the kinematic and structural measurements in a wet-spinning process incorporating both shear and extensional flows. The birefringent responses of fibers under coagulation are compared with an orientation factor incorporated in the constitutive model, from which a superposed structure-optic relationship under varying spinning conditions is identified. Such structural characterizations inferred from the flow dynamics of spinning dopes exhibit strong connections with the mechanical properties of the fully-regenerated fibers, thus enabling to predict the spinning performance in a non-destructive protocol.
RESUMEN
OBJECTIVE: The Finnish Diabetes Risk Score (FINDRISC) includes anthropometric, metabolic, and lifestyle factors that predict type 2 diabetes mellitus. The objective of this study was to evaluate the FINDRISC modified for Latin America (LA-FINDRISC) as a screening tool for persons with impaired glucose metabolism in Ciudad Bolívar, Venezuela. METHODS: Subjects aged between 18 and 70 years of both sexes without known diabetes were invited to participate. After informed consent, they were screened with the LA-FINDRISC questionnaire and then given an oral glucose tolerance test, using the American Diabetes Association criteria for diagnosis. To obtain the cutoff point of LA-FINDRISC for predicting impaired glucose regulation, a receiver operating characteristic curve was constructed. RESULTS: A total of 200 subjects were evaluated, 64.5% female, with a mean age of 35.20 ± 13.84 years. Of these, 158 (79%) did not present with carbohydrate metabolism disorder, while 42 (21%) did. Age (p = 0.0001), body mass index (p = 0.011), and waist circumference (p = 0.031) were significantly higher in subjects with impaired glucose regulation when compared to those without it. There were a significantly greater number of sedentary (p = 0.039) and hypertensive subjects (p = 0.0001), as well as those with a history of glucose >100 mg/dL (p = 0.0001), in the impaired glucose metabolism group. A cutoff LA-FINDRISC of 14 points predicted a high risk of impaired glucose regulation with a sensitivity of 45.2% and a specificity of 89.9%. CONCLUSION: A LA-FINDRISC >14 points had low sensitivity but high specificity for predicting carbohydrate metabolism disorders in this group of patients from Ciudad Bolívar.