Cervical Cancer Classification From Pap Smear Images Using Deep Convolutional Neural Network Models.

As one of the most common female cancers, cervical cancer often develops years after a prolonged and reversible pre-cancerous stage. Traditional classification algorithms used for detection of cervical cancer often require cell segmentation and feature extraction techniques, while convolutional neural network (CNN) models demand a large dataset to mitigate over-fitting and poor generalization problems. To this end, this study aims to develop deep learning models for automated cervical cancer detection that do not rely on segmentation methods or custom features. Due to limited data availability, transfer learning was employed with pre-trained CNN models to directly operate on Pap smear images for a seven-class classification task. Thorough evaluation and comparison of 13 pre-trained deep CNN models were performed using the publicly available Herlev dataset and the Keras package in Google Collaboratory. In terms of accuracy and performance, DenseNet-201 is the best-performing model. The pre-trained CNN models studied in this paper produced good experimental results and required little computing time.

Developments in the detection of diabetic retinopathy: a state-of-the-art review of computer-aided diagnosis and machine learning methods.

The exponential increase in the number of diabetics around the world has led to an equally large increase in the number of diabetic retinopathy (DR) cases which is one of the major complications caused by diabetes. Left unattended, DR worsens the vision and would lead to partial or complete blindness. As the number of diabetics continue to increase exponentially in the coming years, the number of qualified ophthalmologists need to increase in tandem in order to meet the demand for screening of the growing number of diabetic patients. This makes it pertinent to develop ways to automate the detection process of DR. A computer aided diagnosis system has the potential to significantly reduce the burden currently placed on the ophthalmologists. Hence, this review paper is presented with the aim of summarizing, classifying, and analyzing all the recent development on automated DR detection using fundus images from 2015 up to this date. Such work offers an unprecedentedly thorough review of all the recent works on DR, which will potentially increase the understanding of all the recent studies on automated DR detection, particularly on those that deploys machine learning algorithms. Firstly, in this paper, a comprehensive state-of-the-art review of the methods that have been introduced in the detection of DR is presented, with a focus on machine learning models such as convolutional neural networks (CNN) and artificial neural networks (ANN) and various hybrid models. Each AI will then be classified according to its type (e.g. CNN, ANN, SVM), its specific task(s) in performing DR detection. In particular, the models that deploy CNN will be further analyzed and classified according to some important properties of the respective CNN architectures of each model. A total of 150 research articles related to the aforementioned areas that were published in the recent 5 years have been utilized in this review to provide a comprehensive overview of the latest developments in the detection of DR. Supplementary Information: The online version contains supplementary material available at 10.1007/s10462-022-10185-6.

Tchebichef moment based restoration of Gaussian blurred images.

With the knowledge of how edges vary in the presence of a Gaussian blur, a method that uses low-order Tchebichef moments is proposed to estimate the blur parameters: sigma (σ) and size (w). The difference between the Tchebichef moments of the original and the reblurred images is used as feature vectors to train an extreme learning machine for estimating the blur parameters (σ,w). The effectiveness of the proposed method to estimate the blur parameters is examined using cross-database validation. The estimated blur parameters from the proposed method are used in the split Bregman-based image restoration algorithm. A comparative analysis of the proposed method with three existing methods using all the images from the LIVE database is carried out. The results show that the proposed method in most of the cases performs better than the three existing methods in terms of the visual quality evaluated using the structural similarity index.

Correlation between subjective and objective assessment of magnetic resonance (MR) images.

Medical Image Quality Assessment (IQA) plays an important role in assisting and evaluating the development of any new hardware, imaging sequences, pre-processing or post-processing algorithms. We have performed a quantitative analysis of the correlation between subjective and objective Full Reference - IQA (FR-IQA) on Magnetic Resonance (MR) images of the human brain, spine, knee and abdomen. We have created a MR image database that consists of 25 original reference images and 750 distorted images. The reference images were distorted with six types of distortions: Rician Noise, Gaussian White Noise, Gaussian Blur, DCT compression, JPEG compression and JPEG2000 compression, at various levels of distortion. Twenty eight subjects were chosen to evaluate the images resulting in a total of 21,700 human evaluations. The raw scores were then converted to Difference Mean Opinion Score (DMOS). Thirteen objective FR-IQA metrics were used to determine the validity of the subjective DMOS. The results indicate a high correlation between the subjective and objective assessment of the MR images. The Noise Quality Measurement (NQM) has the highest correlation with DMOS, where the mean Pearson Linear Correlation Coefficient (PLCC) and Spearman Rank Order Correlation Coefficient (SROCC) are 0.936 and 0.938 respectively. The Universal Quality Index (UQI) has the lowest correlation with DMOS, where the mean PLCC and SROCC are 0.807 and 0.815 respectively. Student's T-test was used to find the difference in performance of FR-IQA across different types of distortion. The superior IQAs tested statistically are UQI for Rician noise images, Visual Information Fidelity (VIF) for Gaussian blur images, NQM for both DCT and JPEG compressed images, Peak Signal-to-Noise Ratio (PSNR) for JPEG2000 compressed images.

Real-Time Head Pose Tracking with Online Face Template Reconstruction.

We propose a real-time method to accurately track the human head pose in the 3-dimensional (3D) world. Using a RGB-Depth camera, a face template is reconstructed by fitting a 3D morphable face model, and the head pose is determined by registering this user-specific face template to the input depth video.

Visual Quality Evaluation of Image Object Segmentation: Subjective Assessment and Objective Measure.

A visual quality evaluation of image object segmentation as one member of the visual quality evaluation family has been studied over the years. Researchers aim at developing the objective measures that can evaluate the visual quality of object segmentation results in agreement with human quality judgments. It is also significant to construct a platform for evaluating the performance of the objective measures in order to analyze their pros and cons. In this paper, first, we present a novel subjective object segmentation visual quality database, in which a total of 255 segmentation results were evaluated by more than thirty human subjects. Then, we propose a novel full-reference objective measure for an object segmentation visual quality evaluation, which involves four human visual properties. Finally, our measure is compared with some state-of-the-art objective measures on our database. The experiment demonstrates that the proposed measure performs better in matching subjective judgments. Moreover, the database is available publicly for other researchers in the field to evaluate their measures.

Moment domain representation of nonblind image deblurring.

In this paper, we propose the use of geometric moments to the field of nonblind image deblurring. Using the developed relationship of geometric moments for original and blurred images, a mathematical formulation based on the Euler-Lagrange identity and variational techniques is proposed. It uses an iterative procedure to deblur the image in moment domain. The theoretical framework is validated by a set of experiments. A comparative analysis of the results obtained using the spatial and moment domains are evaluated using a quality assessment method known as the Blind/Reference-less Image Spatial Quality Evaluator (BRISQUE). The results show that the proposed method yields a higher quality score when compared with the spatial domain method for the same number of iterations.

Geometric moment extraction equipment for image processing applications.

An equipment for calculating 2nd, 3rd, and higher order geometric moments by using accumulators, adders, subtractors, and multiplier blocks has been presented. The performance analysis of the proposed equipment with the existing systems in terms of speed and power dissipation has been carried out and has been shown that the computational time to calculate the geometric moments is reduced to half and the power dissipation is reduced by a factor of about 3 at a clock frequency of 10 MHz. The hardware has been implemented in BSIM4.3.0 50 nm technology operating at 1 V and its functionality has been verified using P-Spice simulator.

Recursive formula to compute Zernike radial polynomials.

In optics, Zernike polynomials are widely used in testing, wavefront sensing, and aberration theory. This unique set of radial polynomials is orthogonal over the unit circle and finite on its boundary. This Letter presents a recursive formula to compute Zernike radial polynomials using a relationship between radial polynomials and Chebyshev polynomials of the second kind. Unlike the previous algorithms, the derived recurrence relation depends neither on the degree nor on the azimuthal order of the radial polynomials. This leads to a reduction in the computational complexity.

Image analysis using hahn moments.

This paper shows how Hahn moments provide a unified understanding of the recently introduced Chebyshev and Krawtchouk moments. The two latter moments can be obtained as particular cases of Hahn moments with the appropriate parameter settings, and this fact implies that Hahn moments encompass all their properties. The aim of this paper is twofold: 1) To show how Hahn moments, as a generalization of Chebyshev and Krawtchouk moments, can be used for global and local feature extraction, and 2) to show how Hahn moments can be incorporated into the framework of normalized convolution to analyze local structures of irregularly sampled signals.

An efficient method for the computation of Legendre moments.

Legendre moments are continuous moments, hence, when applied to discrete-space images, numerical approximation is involved and error occurs. This paper proposes a method to compute the exact values of the moments by mathematically integrating the Legendre polynomials over the corresponding intervals of the image pixels. Experimental results show that the values obtained match those calculated theoretically, and the image reconstructed from these moments have lower error than that of the conventional methods for the same order. Although the same set of exact Legendre moments can be obtained indirectly from the set of geometric moments, the computation time taken is much longer than the proposed method.

Selection of a Subset of EEG Channels using PCA to classify Alcoholics and Non-alcoholics.

The Principal Component Analysis (PCA) is proposed as feature selection method in choosing a subset of channels for Visual Evoked Potentials (VEP). The selected channels are to preserve as much information present as compared to the full set of 61 channels as possible. The method is applied to classify two categories of subjects: alcoholics and non-alcoholics. The electroencephalogram (EEG) was recorded when the subjects were presented with single trial visual stimuli. The proposed method is successful in selecting the a subset of channels that contribute to high accuracy in the classification of alcoholics and non-alcoholics.

Noise removal of ECG S signals using Legendre moments.

This paper proposes a method to remove the noise in the ECG (Electrocardiogram) signals using Legendre moments. Noise is removed in the reconstructed ECG signals when lower order Legendre moments are used. RMSE (Root Mean Square Error) is used as the distortion measure for the reconstructed ECG signals. With sampling rate of 256 Hz and number of moments used is 13% of the data in each interval, experimental results show that reconstruction of ECG signal using Legendre moments can produce a smoother signal without noise while maintaining signal quality that is acceptable to cardiologist.

Image analysis by Krawtchouk moments.

In this paper, a new set of orthogonal moments based on the discrete classical Krawtchouk polynomials is introduced. The Krawtchouk polynomials are scaled to ensure numerical stability, thus creating a set of weighted Krawtchouk polynomials. The set of proposed Krawtchouk moments is then derived from the weighted Krawtchouk polynomials. The orthogonality of the proposed moments ensures minimal information redundancy. No numerical approximation is involved in deriving the moments, since the weighted Krawtchouk polynomials are discrete. These properties make the Krawtchouk moments well suited as pattern features in the analysis of two-dimensional images. It is shown that the Krawtchouk moments can be employed to extract local features of an image, unlike other orthogonal moments, which generally capture the global features. The computational aspects of the moments using the recursive and symmetry properties are discussed. The theoretical framework is validated by an experiment on image reconstruction using Krawtchouk moments and the results are compared to that of Zernike, pseudo-Zernike, Legendre, and Tchebyscheff moments. Krawtchouk moment invariants are constructed using a linear combination of geometric moment invariants; an object recognition experiment shows Krawtchouk moment invariants perform significantly better than Hu's moment invariants in both noise-free and noisy conditions.

A new brain-computer interface design using fuzzy ARTMAP.

This paper proposes a new brain-computer interface (BCI) design using fuzzy ARTMAP (FA) neural network, as well as an application of the design. The objective of this BCI-FA design is to classify the best three of the five available mental tasks for each subject using power spectral density (PSD) values of electroencephalogram (EEG) signals. These PSD values are extracted using the Wiener-Khinchine and autoregressive methods. Ten experiments employing different triplets of mental tasks are studied for each subject. The findings show that the average BCI-FA outputs for four subjects gave less than 6% of error using the best triplets of mental tasks identified from the classification performances of FA. This implies that the BCI-FA can be successfully used with a tri-state switching device. As an application, a proposed tri-state Morse code scheme could be utilized to translate the outputs of this BCI-FA design into English letters. In this scheme, the three BCI-FA outputs correspond to a dot and a dash, which are the two basic Morse code alphabets and a space to denote the end (or beginning) of a dot or a dash. The construction of English letters using this tri-state Morse code scheme is determined only by the sequence of mental tasks and is independent of the time duration of each mental task. This is especially useful for constructing letters that are represented as multiple dots or dashes. This combination of BCI-FA design and the tri-state Morse code scheme could be developed as a communication system for paralyzed patients.