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1.
J Trauma Nurs ; 30(3): 164-170, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37144807

RESUMEN

BACKGROUND: Ongoing evaluation of massive transfusion protocol adherence is critical to ensure better trauma patient outcomes. OBJECTIVE: This quality improvement initiative aimed to determine provider adherence to a recently revised massive transfusion protocol and its relationship to clinical outcomes among trauma patients requiring massive transfusion. METHODS: A retrospective, descriptive, correlational design was used to determine the association between provider adherence to a recently revised massive transfusion protocol and clinical outcomes in trauma patients with hemorrhage treated at a Level I trauma center from November 2018 to October 2020. Patient characteristics, provider massive transfusion protocol adherence, and patient outcomes were assessed. Patient characteristics and massive transfusion protocol adherence associations with 24-hr survival and survival to discharge were determined using bivariate statistical methods. RESULTS: A total of 95 trauma patients with massive transfusion protocol activation were evaluated. Of the 95, 71 (75%) survived the initial 24 hr following massive transfusion protocol activation and 65 (68%) survived to discharge. Based on protocol applicable items, the median massive transfusion protocol overall adherence rate per patient was 75% (IQR = 57.1-85.7) for the 65 survivors and 25% (IQR = 12.5-50.0) for the 21 nonsurvivors to discharge whose death occurred at least 1 hr after massive transfusion protocol activation (p < .001). CONCLUSION: Findings indicate the importance of ongoing evaluations of adherence to massive transfusion protocols in hospital trauma settings to target areas for improvement.


Asunto(s)
Transfusión Sanguínea , Heridas y Lesiones , Humanos , Estudios Retrospectivos , Transfusión Sanguínea/métodos , Hemorragia/terapia , Centros Traumatológicos , Resucitación/métodos , Heridas y Lesiones/diagnóstico , Heridas y Lesiones/terapia
2.
JMIR Form Res ; 7: e40359, 2023 Apr 20.
Artículo en Inglés | MEDLINE | ID: mdl-36962700

RESUMEN

BACKGROUND: Given the importance of self-management in type 2 diabetes mellitus (T2DM), a major aspect of health is providing diabetes self-management education and support. Known barriers include access, availability, and the lack of follow through on referral to education programs. Virtual education and support have increased in use over the last few years. OBJECTIVE: The purpose of the Diabetes Learning in a Virtual Environment (LIVE) study was to compare the effects of the LIVE intervention (educational 3D world) to a diabetes self-management education and support control website on diet and physical activity behaviors and behavioral and metabolic outcomes in adults with T2DM over 12 months. METHODS: The LIVE study was a 52-week multisite randomized controlled trial with longitudinal repeated measures. Participants were randomized to LIVE (n=102) or a control website (n=109). Both contained the same educational materials, but the virtual environment was synchronous and interactive, whereas the control was a flat website. Data were collected at baseline and 3, 6, and 12 months using surveys and clinical, laboratory, and Fitbit measures. Descriptive statistics included baseline characteristics and demographics. The effects of the intervention were initially examined by comparing the means and SDs of the outcomes across the 4 time points between study arms, followed by multilevel modeling on trajectories of the outcomes over the 12 months. RESULTS: This trial included 211 participants who consented. The mean age was 58.85 (SD 10.1) years, and a majority were White (127/211, 60.2%), non-Hispanic (198/211, 93.8%), married (107/190, 56.3%), and female (125/211, 59.2%). Mean hemoglobin A1c (HbA1c) level at baseline was 7.64% (SD 1.79%) and mean BMI was 33.51 (SD 7.25). We examined weight loss status versus randomized group, where data with no weight change were eliminated, and the LIVE group experienced significantly more weight loss than the control group (P=.04). There were no significant differences between groups in changes in physical activity and dietary outcomes (all P>.05), but each group showed an increase in physical activity. Both groups experienced a decrease in mean HbA1c level, systolic and diastolic blood pressure, cholesterol, and triglycerides over the course of 12 months of study participation, including those participants whose baseline HbA1c level was 8.6% or higher. CONCLUSIONS: This study confirmed that there were minor positive changes on glycemic targets in both groups over the 12-month study period; however, the majority of the participants began with optimal HbA1c levels. We did find clinically relevant metabolic changes in those who began with an HbA1c level >8.6% in both groups. This study provided a variety of resources to our participants in both study groups, and we conclude that a toolkit with a variety of services would be helpful to improving self-care in the future for persons with T2DM. TRIAL REGISTRATION: ClinicalTrials.gov NCT02040038; https://clinicaltrials.gov/ct2/show/NCT02040038.

3.
J Perianesth Nurs ; 38(4): 543-552, 2023 08.
Artículo en Inglés | MEDLINE | ID: mdl-36599790

RESUMEN

PURPOSE: The purpose of this project was to improve the consistency of verbal and written discharge instructions for women of childbearing age (13-55 years) taking hormonal contraceptives who receive aprepitant perioperatively, to address the need to use a secondary form of birth control for 28 days, as well as to increase the knowledge and confidence of Registered Nurses when providing discharge instructions. DESIGN: This quality improvement project used a pre-/postdesign to evaluate two separate groups of patients and registered nurses. METHODS: The patient sample consisted of 30 total women of childbearing age who received aprepitant during the perioperative period (15 pre and 15 post). The PACU nurse sample included 15 ambulatory surgery center nurses and 58 main hospital nurses for a combined sample of 73 PACU nurses. The PACU nurses were provided with educational in-service regarding information about aprepitant and its drug interactions. PACU nurses were additionally instructed to provide patient discharge instructions using both a written and verbal format. Patients were called postoperatively before and after both the written after visit summary (AVS) changes and the PACU nurse in-services, PACU nurses were evaluated on their knowledge, confidence, and frequency of discharge teaching before and after their educational in-service. The PACU nurses were surveyed 90 days after the intervention to assess their long-term knowledge retention. FINDINGS: There was a significant increase in nurse knowledge about aprepitant from preimplementation to postimplementation (61.39% vs 81.95%, P < .001). Nursing knowledge showed a nonsignificant decline at 90-days postimplementation (81.95% vs 73.68%, P = .096) although remained significantly higher than preimplementation scores (73.68% vs 61.39%, P = .003). There was an overall 33.3% increase in the percentage of patients who were able to recall receiving aprepitant and the need to use a secondary form of birth control when comparing the preintervention group to the postintervention group (26.7% vs 60%, P = .123). CONCLUSIONS: The findings suggest that providing a standardized presentation about aprepitant may improve the PACU nurses' ability to verbalize key information about aprepitant, including the need for patients to use a secondary form of birth control. This increase in nursing knowledge and confidence, along with improved written discharge instructions, may have led to improved patient comprehension of aprepitant discharge education. Additionally, there was an increase in the percentage of patients who were able to recall the need to use a secondary form birth control for 28 days, to reduce the likelihood of an unintentional pregnancy.


Asunto(s)
Anticoncepción Hormonal , Enfermeras y Enfermeros , Humanos , Femenino , Adolescente , Adulto Joven , Adulto , Persona de Mediana Edad , Aprepitant , Competencia Clínica , Educación del Paciente como Asunto
4.
Nurs Outlook ; 70(6): 846-855, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36396500

RESUMEN

BACKGROUND: Doctor of Nursing Practice (DNP) programs require a project to improve outcomes in a health care setting. However, dissemination methods vary. PURPOSE: This evaluation examined benefits and challenges associated with submitting project manuscripts to a peer-reviewed health care journal in a DNP program with this requirement. METHODS: Benefits and challenges were assessed with surveys completed by 85 DNP program alumni and 28 DNP mentors and by interviewing 5 faculty who teach in the DNP program and 5 editors of nursing journals. FINDINGS: Benefits of completing a manuscript included sharing knowledge to improve health care outcomes and enhancing nursing scholarship. Among alumni, 81% reported manuscript development was beneficial and 69% published their work. Most students, most faculty, and all editors endorsed the requirement with alternatives for projects lacking rigor or innovation. Challenges included need for faculty involvement and editorial/statistical resources. DISCUSSION: Despite challenges, there are benefits of publishing rigorous and innovative DNP work.


Asunto(s)
Educación de Postgrado en Enfermería , Publicaciones Periódicas como Asunto , Estudiantes de Enfermería , Humanos , Docentes de Enfermería , Atención a la Salud
5.
PLoS One ; 17(10): e0274749, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36219615

RESUMEN

BACKGROUND: Postoperative pulmonary complications (PPCs) are an important cause of perioperative morbidity and mortality. Although risk factors for PPCs have been identified in high-income countries, less is known about PPCs and their risk factors in low- and middle-income countries, such as South Africa. This study examined the incidence of PPCs and their associated risk factors among general surgery patients in a public hospital in the province of KwaZulu-Natal, South Africa to inform future quality improvement initiatives to decrease PPCs in this clinical population. METHODS: A retrospective secondary analysis of adult patients with general surgery admissions from January 1, 2013 to December 31, 2017 was conducted using data from the health system's Hybrid Electronic Medical Registry. The sample was comprised of 5352 general surgery hospitalizations. PPCs included pneumonia, atelectasis, acute respiratory distress syndrome, pulmonary edema, pulmonary embolism, prolonged ventilation, hemothorax, pneumothorax, and other respiratory morbidity which encompassed empyema, aspiration, pleural effusion, bronchopleural fistula, and lower respiratory tract infection. Risk factors examined were age, tobacco use, number and type of pre-existing comorbidities, emergency surgery, and number and type of surgeries. Bivariate and multivariable logistic regression models were conducted to identify risk factors for developing a PPC. RESULTS: The PPC rate was 7.8%. Of the 418 hospitalizations in which a patient developed a PPC, the most common type of PPC was pneumonia (52.4%) and the mortality rate related to the PPC was 11.7%. Significant risk factors for a PPC were increasing age, greater number of comorbidities, emergency surgery, greater number of general surgeries, and abdominal surgery. CONCLUSIONS: PPCs are common in general surgery patients in low- and middle-income countries, with similar rates observed in high-income countries. These complications worsen patient outcomes and increase mortality. Quality improvement initiatives that employ resource-conscious methods are needed to reduce PPCs in low- and middle-income countries.


Asunto(s)
Enfermedades Pulmonares , Neumonía , Atelectasia Pulmonar , Adulto , Humanos , Enfermedades Pulmonares/epidemiología , Enfermedades Pulmonares/etiología , Neumonía/complicaciones , Neumonía/etiología , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Estudios Retrospectivos , Factores de Riesgo , Sudáfrica/epidemiología
6.
AANA J ; 90(3): 215-223, 2022 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-35604864

RESUMEN

Utilization of opioids for acute pain control during surgical procedures is commonplace for anesthesia providers. Opioid use is associated with many undesirable side effects, including opioid use disorder. Opioid-free anesthesia for surgical procedures using a multimodal approach can reduce these side effects. This quality improvement project evaluated the implementation of an opioid-free anesthesia protocol for elective abdominal surgical procedures in a community hospital. The project had specific aims of detecting a reduction in opioid consumption in the operating room and the first 30 minutes in the post anesthesia recovery unit (PACU) while confirming pain relief comparable to that seen with opioid analgesia. Implementation of the quality improvement protocol resulted in a 79% reduction in the number of patients who received opioids during surgery and provided pain relief through the first 30 minutes in PACU comparable to anesthesia that included opioids. This project confirmed that an opioid-free anesthesia protocol could be successfully implemented within a community hospital for healthy adults undergoing elective abdominal surgery.


Asunto(s)
Analgésicos Opioides , Anestesia , Músculos Abdominales , Adulto , Analgésicos Opioides/uso terapéutico , Hospitales Comunitarios , Humanos , Dolor Postoperatorio/tratamiento farmacológico , Dolor Postoperatorio/prevención & control
7.
J Perianesth Nurs ; 37(4): 445-451, 2022 08.
Artículo en Inglés | MEDLINE | ID: mdl-35305914

RESUMEN

PURPOSE: The quality improvement (QI) project implemented a postoperative nausea and vomiting (PONV) risk screening tool and introduced a risk-tailored prophylactic guideline to identify patients at risk for PONV and aimed to minimize PONV adverse events. DESIGN: This project represents the initial PDSA (Plan-Do-Study-Act) cycle for quality improvement with use of a pre-post design with two independent groups designed to compare PONV rates before and after implementation of an Apfel Simplified Risk Score screening and prophylactic guideline intervention. METHODS: The project implemented the screening of patient PONV risk using the Apfel Simplified Risk Score and a combination antiemetic drug class prophylactic guideline for adult patients undergoing elective same-day surgery procedures. An online education module was provided to anesthesia professionals and was reviewed in-person with the relevant anesthesia professional team prior to surgery. Pre-implementation (N=107) PONV outcomes were collected. Data collected from a retrospective chart review was used to compare pre- and post-implementation PONV rates (N=96) and determine post-implementation anesthesia professional adherence to guideline recommendations. FINDINGS: Forty percent of screened patients were identified as having an increased PONV risk with an Apfel Simplified Risk Score of 3 or 4. The PONV rates for the pre-group (19.6%) and post-group (22.9%) did not significantly differ (P=.5567). Anesthesia professional adherence to administration of the recommended number of antiemetic drug classes was 89.6%. A Spearman point-biserial correlation analysis indicated a significant positive relationship between Apfel Simplified Risk Score and PONV onset in the post-group (rs=0.21, P=.0428). CONCLUSIONS: The Apfel Simplified Risk Score and prophylactic guideline increased identification of patients at risk for PONV but did not affect PONV rate despite a high anesthesia professional adherence to the guideline recommendations.


Asunto(s)
Antieméticos , Náusea y Vómito Posoperatorios , Adulto , Procedimientos Quirúrgicos Ambulatorios , Antieméticos/uso terapéutico , Humanos , Náusea y Vómito Posoperatorios/tratamiento farmacológico , Náusea y Vómito Posoperatorios/prevención & control , Estudios Retrospectivos , Factores de Riesgo
8.
J Perianesth Nurs ; 36(4): 351-358, 2021 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-33745828

RESUMEN

PURPOSE: The purpose of this quality improvement project was to improve consistency of discharge teaching in women who used progesterone-containing hormonal contraceptive medications and received sugammadex during general anesthesia, as there is a risk of unintended pregnancy for 1 week after administration of sugammadex. DESIGN: This project used a predesign and postdesign using two separate sample groups of patients and postanesthesia care unit (PACU) nurses. METHODS: The sample consisted of 31 total women of childbearing age and 59 PACU nurses. Simplification of sugammadex discharge instructions was achieved by incorporating evidence-based recommendations for electronic discharge instructions and nursing education. PACU nurses were educated and surveyed before and after regarding frequency of discharge teaching, clarity, and comprehension of the after-visit summary and knowledge of sugammadex. Patients were called via telephone postoperatively to assess recall of sugammadex discharge teaching. FINDINGS: Postoperative patient phone calls identified a small increase in patient recall of discharge instructions from 5 of 14 patients (35.7%) before implementation to 7 of 17 after implementation (41.2%). PACU nurse surveys indicated an increase in self-reported frequency of sugammadex discharge teaching (34.8% vs 64.2%, P = .024) and that new discharge instructions contained more clear, comprehensive information as compared with previous instructions (29.4% vs 75.5%, P = .001). CONCLUSIONS: This quality improvement project successfully implemented more consistent and comprehensive discharge instructions for women who receive sugammadex intraoperatively. Limitations of the project included a small sample size and short implementation intervals. As a result of switching to uniform discharge instructions, more patients received important discharge teaching from PACU nurses, and the percentage of patients who recalled this information increased.


Asunto(s)
Anticoncepción Hormonal , Mejoramiento de la Calidad , Anestesia General , Femenino , Humanos , Persona de Mediana Edad , Embarazo , Sugammadex , Encuestas y Cuestionarios
9.
Public Health Nurs ; 38(4): 671-674, 2021 07.
Artículo en Inglés | MEDLINE | ID: mdl-33682156

RESUMEN

More than 80 percent of African American women struggle with overweight and obesity. We implemented a 5-week physical activity intervention using Facebook™ and pedometers with African American women. Twenty-seven African American women participated in a single-group pre/post design intervention to promote walking and physical activity. Participants were given access to a private Facebook™ group along with a free Omron Alvita pedometer. The five-week intervention challenged participants to increase weekly daily steps and the number of days they were physically active. At the end of the intervention, participants had significantly increased their weekly steps by 190% as compared to baseline (p = .005). Nearly, 80% of participants reported being active two or more days per week as compared to baseline (35.7%). Technologies such as social media and pedometers can assist in educating individuals and improving physical activity. These findings are relevant to public health nurses when implementing programs to increase physical activity for African American women.


Asunto(s)
Actigrafía , Negro o Afroamericano , Ejercicio Físico , Femenino , Promoción de la Salud , Humanos , Caminata
10.
J Surg Res ; 262: 47-56, 2021 06.
Artículo en Inglés | MEDLINE | ID: mdl-33548673

RESUMEN

BACKGROUND: The trauma burden in South Africa is significant. The objective of this project was to investigate the incidence of posttrauma pulmonary complications (PPCs) and to identify patient, health risks, and hospital factors, which predispose trauma patients to develop PPCs hospital in Pietermaritzburg, South Africa. METHODS: The design was a retrospective secondary data analysis of patients who presented as a trauma admission via the health systems' Hybrid Electronic Medical Registry. The final data set included 6382 trauma admissions. RESULTS: The PPC rate was 9.4% for patients with a surgical intervention versus 1.9% for those without a surgical intervention. Of the total 289 PPCs reported, the most common included pneumonia or atelectasis (46.4%) and prolonged ventilation (36.0%). The risk of developing a PPC was statistically significantly (P < 0.0001) associated with surgical intervention and the number of surgeries. CONCLUSIONS: The trauma burden in South Africa requires complex medical and surgical interventions. The incidence of PPCs is significantly associated with surgical intervention. With the increasing demand to harness data and improve patient care, the Hybrid Electronic Medical Registry proves to be a driver for quality improvement.


Asunto(s)
Análisis de Datos , Enfermedades Pulmonares/etiología , Heridas y Lesiones/complicaciones , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Recuperación Mejorada Después de la Cirugía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Neumonía/etiología , Atelectasia Pulmonar/etiología , Estudios Retrospectivos , Factores de Riesgo , Adulto Joven
12.
Menopause ; 27(11): 1295-1301, 2020 11.
Artículo en Inglés | MEDLINE | ID: mdl-33110046

RESUMEN

OBJECTIVE: Genitourinary syndrome of menopause (GSM) affects nearly 50% of postmenopausal women. Yet women fail to recognize GSM as a chronic condition and are reluctant to discuss their vaginal or sexual complaints with a health care provider. This quality improvement project implemented the Day-to-Day Impact of Vaginal Aging (DIVA) questionnaire to improve the identification and diagnosis of GSM in women ≥ 45 years of age presenting for an annual wellness examination or a vulvovaginal/genitourinary complaint. METHODS: From October 2019 to February 2020, the DIVA questionnaire was distributed in a large women's health practice setting to women ≥ 45 years of age, for completion before their annual wellness visit or for evaluation of a GSM-related complaint. GSM diagnosis rates during the implementation period were compared with diagnosis rates during a 4-month period immediately preceding the implementation. Data collected during the implementation period were examined to evaluate if GSM diagnosis was more likely in patients who completed the DIVA questionnaire when compared to those women who did not complete the questionnaire. RESULTS: Of the 175 women who met the inclusion criteria, 113 completed the DIVA questionnaire. Completion of the DIVA questionnaire demonstrated a relative percentage increase in GSM diagnosis by 30.7% when compared to the 4-month preimplementation period (10.1% to 13.2%, P = 0.231). This change was not statistically significant. During the implementation period, a statistically significant difference in GSM diagnosis was observed for patients who completed the DIVA questionnaire when compared to those patients who did not complete the questionnaire (37.2% vs 9.7%, P < 0.001). When results were stratified by visit type, women presenting for an annual wellness visit who completed the DIVA questionnaire had a higher GSM diagnosis rate than those who did not complete the questionnaire (37.2% vs 10%, P < 0.001). When results were stratified by menopausal status, GSM diagnosis rates were also more likely for postmenopausal women who completed the DIVA questionnaire when compared to those who did not complete the questionnaire (44.2% vs 8.5%, P < 0.001). CONCLUSIONS: The DIVA questionnaire is a brief, but comprehensive screening tool that can increase GSM identification and treatment, particularly for postmenopausal, and midlife women presenting for an annual wellness visit in a busy women's health practice setting. : Video Summary:http://links.lww.com/MENO/A655.


Video Summary:http://links.lww.com/MENO/A655.


Asunto(s)
Menopausia , Posmenopausia , Envejecimiento , Atrofia/patología , Femenino , Humanos , Encuestas y Cuestionarios , Vagina/patología
13.
Clin Diabetes ; 38(3): 213-221, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-32699469

RESUMEN

A culturally sensitive Healthy Interactions Conversations Maps program was implemented for teaching diabetes self-management education (DSME) to Latinos with type 2 diabetes using peer-led educators in a community health center. Patients were invited to participate in a group care setting to improve access to providers and DSME. Goals were to improve diabetes distress, self-efficacy, and glycemic control as measured by A1C. Significant improvements were found for mean diabetes self-efficacy scores from before (2.53 ± 0.59) to after (2.91 ± 0.50) DSME (P <0.001). Mean A1C decreased significantly from before (9.51 ± 1.72%) to after (8.79 ± 1.68%) DSME (P = 0.043) at the end of the 6-month intervention. Thus, this program was found to be a useful tool for providing DSME in community health clinics serving low-income Latinos.

14.
Clin Diabetes ; 38(2): 152-158, 2020 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-32327887

RESUMEN

Adolescents with type 1 diabetes face self-management challenges that make it difficult for them to achieve good glycemic control. In our population of adolescents with poorly controlled type 1 diabetes, the use of continuous glucose monitoring (CGM) improved patients' glycemic time in range (TIR) and identified hypoglycemia more frequently than with intermittent self-monitoring of blood glucose throughout a 4-week interval. However, the adolescents were unable to synthesize this information to problem-solve or reduce the frequency of hypoglycemic events. Setting SMART (specific, measurable, achievable, relevant, and time-bound) diabetes management goals and providing intensive diabetes education and support could increase adolescents' TIR and prevent hypoglycemia.

16.
Clin Diabetes ; 37(3): 242-249, 2019 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-31371855

RESUMEN

IN BRIEF A1C point-of-care testing (POCT) paired with face-to-face education potentially improves glycemic control in under-resourced populations. In this study, A1C POCT was implemented with same-day face-to-face medication management and education for adults with type 2 diabetes in a public health department in southeastern North Carolina. The combination of POCT, medication management, and education provided together improved glycemic control and decreased clinical inertia in a setting in which access to health care is limited.

17.
AORN J ; 109(3): 336-344, 2019 03.
Artículo en Inglés | MEDLINE | ID: mdl-30811577

RESUMEN

Ineffective communication can contribute to perioperative adverse events even when a safety checklist is used. The purpose of this project was to improve the overall debriefing process of the surgical safety checklist. We included coaches and used the International Classification for Patient Safety for categorizing any opportunities for improvement that were identified during the debriefing process. The results of our project showed an increase in both the total number of debriefings completed and the number of items discussed when completing the debriefing checklist in comparison with the preintervention compliance audits. We concluded that by using a coaching strategy and method to categorize perioperative opportunities for improvement during the debriefing process, there was improved compliance with completing the debriefing process in our facility.


Asunto(s)
Lista de Verificación/métodos , Relaciones Interprofesionales , Grupo de Atención al Paciente , Calidad de la Atención de Salud/normas , Humanos , Quirófanos/organización & administración , Quirófanos/tendencias , Seguridad del Paciente/normas , Desarrollo de Programa/métodos , Mejoramiento de la Calidad
18.
Med. interna (Caracas) ; 35(3): 99-106, 2019. tab, graf
Artículo en Español | LIVECS, LILACS | ID: biblio-1052938

RESUMEN

Los Accidentes de Tránsito (AT) son un problema mundial de salud pública. Existe evidencia de que los individuos que presentan Trastorno por Déficit de Atención e Hiperactividad (TDAH) tienen mayor riesgo de experimentar AT. Objetivos: determinar la presencia del TDAH y evaluar su relación sobre la incidencia de accidentes motociclísticos en pacientes lesionados por esta causa. Método: Estudio de casos transversal, con muestra pareada por sexo y edad con relación 2.1. La población estuvo conformada por pacientes de 18-63 años de cualquier género, ingresados en el área de emergencia u hospitalización debido a accidente en motocicleta y por causa diferente a AT. Fue un estudio de casos, transversal, analítico, basado en la historia clínica de los pacientes, a quienes se aplicó el test de TDAH según el DSM5 y se dividieron entre pacientes que asistían o no por accidentes de motocicleta. Tratamiento estadístico: se realizó estadística descriptiva y para las comparaciones se calculó el riesgo relativo (OR) con intervalos de confianza 95% y se aplicó chi cuadrado. Resultados: 47 fueron casos y 94 controles, se obtuvo una media de 33 ± 11,74 años. El 93,6% de la población fue masculina. Se evi- denció mayor proporción de manifestaciones aso- ciadas a TDAH en los casos respecto a los contro- les (OR=3,00, IC: 95%, p<0,05), siendo el TDAH inatento el más frecuente. Discusión: Los estudios mundiales demuestran una relación entre el TDAH y los accidentes de tránsito en motorizados, lo cual coincide con los hallazgos obtenidos en la presen- te investigación. Conclusión: Existe una asocia- ción positiva entre la presencia de TDAH y una mayor ocurrencia de accidentes de moto. Es importante el conocimiento y diagnóstico precoz de esta patología para contribuir en la prevención de AT en personas que presentan esta condición(AU)


Traffic accidents (TA) are a public health issue worldwide. Every year the mortality rate increases due to these events. It has been demonstrated that individuals with Attention Deficit Hyperactivity Disorder (ADHD) are at greater risk of having TA than healthy individuals. Objectives: to determine the presence of ADHD and evaluate its effect on motorcycle accident's incidence in injured patients due to these acci- dents. Methods: Prospective, transverse, case-control study with sample matched by sex and age; we evaluated 141 patients between 18-63 years-old. The population included patients who were admitted to the emergency ward or hospitalization areas due to motorcycle accidents (cases), and those who were admitted due to a cause different from AT (controls). Results: there were 47 cases and 94 controls. The mean age was 33 ± 11,74 years and 93,6% were men. It was evident that the cases had more ADHD manifestations than the controls (OR=3,00, IC: 95%, p<0,05) being the inattentive ADHD subtype the most frequent findings. Conclusion: There's a positive relationship between having ADHD and a greater motorcycle accident frequency(AU)


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Trastorno por Déficit de Atención con Hiperactividad/diagnóstico , Trastorno por Déficit de Atención con Hiperactividad/tratamiento farmacológico , Motocicletas , Accidentes de Tránsito/mortalidad , Accidentes de Tránsito/psicología , Salud Pública , Medicina Interna
19.
Aging Cell ; 17(6): e12839, 2018 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-30295421

RESUMEN

SIRT1 is an NAD+ -dependent deacetylase that functions in a variety of cells and tissues to mitigate age-associated diseases. However, it remains unknown if SIRT1 also acts to prevent pathological changes that accrue in motor neurons during aging and amyotrophic lateral sclerosis (ALS). In this study, we show that SIRT1 expression decreases in the spinal cord of wild-type mice during normal aging. Using mouse models either overexpressing or lacking SIRT1 in motor neurons, we found that SIRT1 slows age-related degeneration of motor neurons' presynaptic sites at neuromuscular junctions (NMJs). Transcriptional analysis of spinal cord shows an overlap of greater than 90% when comparing alterations during normal aging with changes during ALS, revealing a substantial upregulation in immune and inflammatory response genes and a downregulation of synaptic transcripts. In addition, overexpressing SIRT1 in motor neurons delays progression to end-stage disease in high copy SOD1G93A mice. Thus, our findings suggest that there are parallels between ALS and aging, and interventions to impede aging may also slow the progression of this devastating disease.


Asunto(s)
Envejecimiento/patología , Esclerosis Amiotrófica Lateral/enzimología , Esclerosis Amiotrófica Lateral/patología , Unión Neuromuscular/enzimología , Unión Neuromuscular/patología , Sirtuina 1/metabolismo , Envejecimiento/genética , Esclerosis Amiotrófica Lateral/genética , Animales , Modelos Animales de Enfermedad , Ratones Endogámicos C57BL , Ratones Noqueados , Neuronas Motoras/metabolismo , Neuronas Motoras/patología , Transcripción Genética
20.
J Emerg Nurs ; 44(5): 459-465, 2018 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-29370946

RESUMEN

INTRODUCTION: There is a growing number of mental health illnesses (MHIs) in the nation and no standardization of the medical screening examination (MSE) in the emergency department. Many health care organizations are at the tipping point of discarding a battery of laboratory workups. A triage tool-specific to psychiatric chief complaints and cost effective-is needed for the emergency department. METHODS: A nonexperimental, retrospective overlay of the Triage Algorithm for Psychiatric Screening (TAPS) onto previous psychiatric patients' records was performed to determine the sensitivity and specificity of the TAPS in ruling out acute medical illness. The laboratory test results, length of stay (LOS), and cost of treatment for all psychiatric patients were examined to determine if there was a correlation with their TAPS scores or if the use of the TAPS would have resulted in efficient care and cost savings. RESULTS: This study shows the TAPS tool can be used reliably to rule out acute medical illness in patients with psychiatric chief complaints in a community hospital setting with an on-site inpatient psychiatric unit. The TAPS tool appropriately identified low-acuity patients without significant medical illness (TAPS of 0). As such, the TAPS tool could be used in selected settings to expedite psychiatric care and reduce unnecessary laboratory testing. IMPLICATIONS FOR PRACTICE: The results of this project represent a valuable step forward in improving the triage of adult patients who present to the emergency department with psychiatric chief complaints. A reproducible study of the TAPS method was the next practice step in determining feasibility. Use of the TAPS tool can be a method to decease costs and ED crowding. For research and quality improvement projects in the future, addiction chief complaints should be treated as a separate category from psychiatric or medical complaints, as they meet the criteria of both.


Asunto(s)
Algoritmos , Servicio de Urgencia en Hospital/organización & administración , Tamizaje Masivo/métodos , Trastornos Mentales/diagnóstico , Triaje/métodos , Adulto , Anciano , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Procedimientos Innecesarios
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