RESUMEN
A 1.9-year-old girl was presented to the hospital with dancing eye movements, ataxia, and behavioral disorders. The MRI showed a retroperitoneal tumor (transversal size: 3.9 x 2.5 cm, craniocaudal size: 4.6 cm) extending from T12 to L3 vertebral bodies (Figure), which was suspicious for neuroblastoma. Afterwards, biopsy of the lesion and bone marrow was performed. The initial pathological evaluation (CD56+, PHOX2B+, NKX2-, Ki67 50%-55%, NSE+, CD99-) of the tumor and bone marrow confirmed the diagnosis of poorly differentiated, high-risk neuroblastoma.
Asunto(s)
Neoplasias de la Médula Ósea/secundario , Neuroblastoma/complicaciones , Neuroblastoma/patología , Síndrome de Opsoclonía-Mioclonía/etiología , Antineoplásicos/uso terapéutico , Femenino , Humanos , Recién Nacido , Neuroblastoma/fisiopatología , Síndrome de Opsoclonía-Mioclonía/tratamiento farmacológico , Síndrome de Opsoclonía-Mioclonía/fisiopatologíaRESUMEN
KEY POINTS ⢠Synovial sarcomas are often mistreated with unplanned tumor resection. ⢠Attention from specialists early in the course of SS can minimize the risk of recurrence, metastases, and the necessity for resurgery, all of which are increased with unplanned tumor resection. ⢠Chemotherapy alone does not provide sufficient local control of the tumor. ⢠Resurgery, in conjunction with radiotherapy and chemotherapy, is the best choice of management for this patient.