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1.
J Acoust Soc Am ; 151(6): 3895, 2022 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-35778174

RESUMEN

Probability distributions of acoustic signals propagating through the near-ground atmosphere are simulated by the parabolic equation method. The simulations involve propagation at four angles relative to the mean wind, with frequencies of 100, 200, 400, and 800 Hz. The environmental representation includes realistic atmospheric refractive profiles, turbulence, and ground interactions; cases are considered with and without parametric uncertainties in the wind velocity and surface heat flux. The simulated signals are found to span a broad range of scintillation indices, from near zero to exceeding ten. In the absence of uncertainties, the signal power (or intensity) is fit well by a two-parameter gamma distribution, regardless of the frequency and refractive conditions. When the uncertainties are included, three-parameter distributions, namely, the compound gamma or generalized gamma, are needed for a good fit to the simulation data. The compound gamma distribution appears preferable because its parameters have a straight forward interpretation related to the saturation and modulation of the signal by uncertainties.

2.
BMJ Open ; 12(3): e052681, 2022 03 10.
Artículo en Inglés | MEDLINE | ID: mdl-35273043

RESUMEN

INTRODUCTION: The complex dynamics of the coronavirus disease 2019 (COVID-19) pandemic has made obtaining reliable long-term forecasts of the disease progression difficult. Simple mechanistic models with deterministic parameters are useful for short-term predictions but have ultimately been unsuccessful in extrapolating the trajectory of the pandemic because of unmodelled dynamics and the unrealistic level of certainty that is assumed in the predictions. METHODS AND ANALYSIS: We propose a 22-compartment epidemiological model that includes compartments not previously considered concurrently, to account for the effects of vaccination, asymptomatic individuals, inadequate access to hospital care, post-acute COVID-19 and recovery with long-term health complications. Additionally, new connections between compartments introduce new dynamics to the system and provide a framework to study the sensitivity of model outputs to several concurrent effects, including temporary immunity, vaccination rate and vaccine effectiveness. Subject to data availability for a given region, we discuss a means by which population demographics (age, comorbidity, socioeconomic status, sex and geographical location) and clinically relevant information (different variants, different vaccines) can be incorporated within the 22-compartment framework. Considering a probabilistic interpretation of the parameters allows the model's predictions to reflect the current state of uncertainty about the model parameters and model states. We propose the use of a sparse Bayesian learning algorithm for parameter calibration and model selection. This methodology considers a combination of prescribed parameter prior distributions for parameters that are known to be essential to the modelled dynamics and automatic relevance determination priors for parameters whose relevance is questionable. This is useful as it helps prevent overfitting the available epidemiological data when calibrating the parameters of the proposed model. Population-level administrative health data will serve as partial observations of the model states. ETHICS AND DISSEMINATION: Approved by Carleton University's Research Ethics Board-B (clearance ID: 114596). Results will be made available through future publication.


Asunto(s)
COVID-19 , Algoritmos , Teorema de Bayes , COVID-19/epidemiología , COVID-19/prevención & control , Calibración , Modelos Epidemiológicos , Humanos , SARS-CoV-2
3.
Int J Health Geogr ; 20(1): 36, 2021 08 18.
Artículo en Inglés | MEDLINE | ID: mdl-34407828

RESUMEN

BACKGROUND: There is consensus that planning professionals need clearer guidance on the features that are likely to produce optimal community-wide health benefits. However, much of this evidence resides in academic literature and not in tools accessible to the diverse group of professionals shaping our cities. Incorporating health-related metrics into the planning support systems (PSS) provides an opportunity to apply empirical evidence on built environment relationships with health-related outcomes to inform real-world land use and transportation planning decisions. This paper explores the role of planning support systems (PSS) to facilitate the translation and application of health evidence into urban planning and design practices to create healthy, liveable communities. METHODS: A review of PSS software and a literature review of studies featuring a PSS modelling built environmental features and health impact assessment for designing and creating healthy urban areas was undertaken. Customising existing software, a health impact PSS (the Urban Health Check) was then piloted with a real-world planning application to evaluate the usefulness and benefits of a health impact PSS for demonstrating and communicating potential health impacts of design scenarios in planning practice. RESULTS: Eleven PSS software applications were identified, of which three were identified as having the capability to undertake health impact analyses. Three studies met the inclusion criteria of presenting a planning support system customised to support health impact assessment with health impacts modelled or estimated due to changes to the built environment. Evaluation results indicated the Urban Health Check PSS helped in four key areas: visualisation of how the neighbourhood would change in response to a proposed plan; understanding how a plan could benefit the community; Communicate and improve understanding health of planning and design decisions that positively impact health outcomes. CONCLUSIONS: The use of health-impact PSS have the potential to be transformative for the translation and application of health evidence into planning policy and practice, providing those responsible for the policy and practice of designing and creating our communities with access to quantifiable, evidence-based information about how their decisions might impact community health.


Asunto(s)
Planificación de Ciudades , Salud Pública , Ciudades , Planificación Ambiental , Humanos , Transportes , Salud Urbana
4.
J Acoust Soc Am ; 149(6): 4384, 2021 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-34241466

RESUMEN

Conventional numerical methods can capture the inherent variability of long-range outdoor sound propagation. However, computational memory and time requirements are high. In contrast, machine-learning models provide very fast predictions. This comes by learning from experimental observations or surrogate data. Yet, it is unknown what type of surrogate data is most suitable for machine-learning. This study used a Crank-Nicholson parabolic equation (CNPE) for generating the surrogate data. The CNPE input data were sampled by the Latin hypercube technique. Two separate datasets comprised 5000 samples of model input. The first dataset consisted of transmission loss (TL) fields for single realizations of turbulence. The second dataset consisted of average TL fields for 64 realizations of turbulence. Three machine-learning algorithms were applied to each dataset, namely, ensemble decision trees, neural networks, and cluster-weighted models. Observational data come from a long-range (out to 8 km) sound propagation experiment. In comparison to the experimental observations, regression predictions have 5-7 dB in median absolute error. Surrogate data quality depends on an accurate characterization of refractive and scattering conditions. Predictions obtained through a single realization of turbulence agree better with the experimental observations.

5.
J Acoust Soc Am ; 148(4): EL347, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-33138545

RESUMEN

This Letter considers probability density functions (pdfs) involving products of the complex amplitudes observed at two points (which may, in general, involve separations in space, time, or frequency) in conditions of fully saturated scattering. First, the pdf is derived for the product of the complex amplitude at one point with the conjugate of the complex amplitude at another point. It is shown that the real and imaginary parts of this product each have a variance gamma pdf. Second, expressions are derived for several joint pdfs involving complex amplitude products and powers at two points.

6.
J Acoust Soc Am ; 142(5): 2905, 2017 11.
Artículo en Inglés | MEDLINE | ID: mdl-29195460

RESUMEN

A multilevel (hierarchical) model is devised that separates noise tolerance into variations occurring at the levels of individual listeners and communities. This approach successfully describes the characteristics of real community transportation noise surveys, with the individual- and community-level variations producing distinct statistical signatures, both of which are evident in the surveys. Predictions are provided for quantities such as the probability of annoyance based on the observed noise level and statistical parameters characterizing the community tolerance. Regression analyses are performed using a multilevel, generalized linear model, which provides an appropriate generalization encompassing both no pooling (separate community-by-community analysis) and full pooling (all communities together) of survey data, and enables noise tolerances and their variations at the individual and community levels to be distinguished and quantified. Variations in individual tolerance and sound exposure within communities are found to be larger than variations in tolerance between communities; however, the variations between communities are still significant and observable. Analysis of multiple types of transportation noise with the multilevel model indicates that tolerance is highest for railway noise with low vibrations, followed by roadway noise, airport noise, and railway noise with high vibrations, as consistent with previous studies.


Asunto(s)
Percepción Auditiva , Exposición a Riesgos Ambientales/efectos adversos , Monitoreo del Ambiente/métodos , Genio Irritable , Modelos Estadísticos , Ruido del Transporte/efectos adversos , Humanos
7.
J Cardiothorac Surg ; 11(1): 118, 2016 Aug 02.
Artículo en Inglés | MEDLINE | ID: mdl-27484472

RESUMEN

BACKGROUND: The purpose of this study is (1) to define the proportion of patients undergoing emergent open repair of thoracic aortic dissection admitted directly through the emergency room versus those transferred from outside hospitals and (2) to determine if a volume-outcomes relationship exists for those patients across admission types. METHODS: De-identified patient-level data was obtained from the Nationwide Inpatient Sample (2004-2008). Patients undergoing emergent aortic surgery for thoracic aortic dissection (n = 1,507) were identified by ICD-9 codes and stratified by annual center volume into low volume (≤5 cases/year) (n = 963; 63.9 %), intermediate volume (6-10 cases/year) (n = 370; 24.5 %), and high volume (≥11 cases/year) (n = 174; 11.6 %) groups. The analysis was further stratified by admission type: direct admission (DA), transfer admission (TA), and other. The primary outcome was in-hospital mortality. Multivariate logistic regression analysis was performed comparing outcomes between high vs low and high vs intermediate volume centers. RESULTS: Overall in-hospital mortality was 21.8 % (n = 328/1,507). Absolute percent mortality at high volume centers was significantly lower (12.6 %) than at medium (20.6 %) and low volume (23.9 %) centers. For DA patients, mortality was 10.6, 21.4, and 24.0 % for high, medium, and low volume centers respectively. For TA patients, mortality was 10.2, 12.7, and 23.5 % for high, medium, and low volume centers, respectively. Multivariate analysis suggested that patients in low volume center were more likely to die compared to high volume center (Odds Ratio 2.06, 95 % CI 1.25 - 3.38, p = 0.004). Admission source was not associated with increased mortality. CONCLUSIONS: Direct admissions comprise the largest proportion of dissections regardless of volume strata, and they comprise the largest proportion in the low and intermediate volume cohorts. Admission to low volume center is an independent risk factor for increased mortality. Patients transferred to high volume centers from low volume centers have similar outcome as direct admits in terms of mortality.


Asunto(s)
Aneurisma de la Aorta Torácica/cirugía , Disección Aórtica/cirugía , Hospitalización/estadística & datos numéricos , Transferencia de Pacientes/estadística & datos numéricos , Adulto , Anciano , Disección Aórtica/mortalidad , Aneurisma de la Aorta Torácica/mortalidad , Femenino , Mortalidad Hospitalaria , Humanos , Masculino , Persona de Mediana Edad , Admisión del Paciente/estadística & datos numéricos , Factores de Riesgo , Resultado del Tratamiento , Estados Unidos/epidemiología
8.
J Acoust Soc Am ; 139(5): 2640, 2016 05.
Artículo en Inglés | MEDLINE | ID: mdl-27250158

RESUMEN

Many outdoor sound propagation models exist, ranging from highly complex physics-based simulations to simplified engineering calculations, and more recently, highly flexible statistical learning methods. Several engineering and statistical learning models are evaluated by using a particular physics-based model, namely, a Crank-Nicholson parabolic equation (CNPE), as a benchmark. Narrowband transmission loss values predicted with the CNPE, based upon a simulated data set of meteorological, boundary, and source conditions, act as simulated observations. In the simulated data set sound propagation conditions span from downward refracting to upward refracting, for acoustically hard and soft boundaries, and low frequencies. Engineering models used in the comparisons include the ISO 9613-2 method, Harmonoise, and Nord2000 propagation models. Statistical learning methods used in the comparisons include bagged decision tree regression, random forest regression, boosting regression, and artificial neural network models. Computed skill scores are relative to sound propagation in a homogeneous atmosphere over a rigid ground. Overall skill scores for the engineering noise models are 0.6%, -7.1%, and 83.8% for the ISO 9613-2, Harmonoise, and Nord2000 models, respectively. Overall skill scores for the statistical learning models are 99.5%, 99.5%, 99.6%, and 99.6% for bagged decision tree, random forest, boosting, and artificial neural network regression models, respectively.

9.
Nanotechnology ; 27(12): 125501, 2016 Mar 29.
Artículo en Inglés | MEDLINE | ID: mdl-26883303

RESUMEN

During dynamic atomic force microscopy (AFM), the deflection of a scanning cantilever generates multiple frequency terms due to the nonlinear nature of AFM tip-sample interactions. Even though each frequency term is reasonably expected to encode information about the sample, only the fundamental frequency term is typically decoded to provide topographic mapping of the measured surface. One of main reasons for discarding higher harmonic signals is their low signal-to-noise ratio. Here, we introduce a new design concept for multi-harmonic AFM, exploiting intentional nonlinear internal resonance for the enhancement of higher harmonics. The nonlinear internal resonance, triggered by the non-smooth tip-sample dynamic interactions, results in nonlinear energy transfers from the directly excited fundamental bending mode to the higher-frequency mode and, hence, enhancement of the higher harmonic of the measured response. It is verified through detailed theoretical and experimental study that this AFM design can robustly incorporate the required internal resonance and enable high-frequency AFM measurements. Measurements on an inhomogeneous polymer specimen demonstrate the efficacy of the proposed design, namely that the higher harmonic of the measured response is capable of enhanced simultaneous topography imaging and compositional mapping, exhibiting less crosstalk with an abrupt height change.

10.
Artículo en Inglés | MEDLINE | ID: mdl-26056500

RESUMEN

OBJECTIVES: This study examines outcomes in a national sample of patients undergoing isolated aortic valve replacement (AVR) for aortic stenosis, with particular focus on advanced-age patients and those with extreme severity of comorbid illness (SOI). METHODS: Data were obtained from the Nationwide Inpatient Sample and included all patients undergoing AVRs performed from January 1, 2006 to December 31, 2008. Patients with major concomitant cardiac procedures, as well as those aged, 20 years, and those with infective endocarditis or aortic insufficiency without aortic stenosis, were excluded from analysis. The analysis included 13,497 patients. Patients were stratified by age and further stratified by All Patient Refined Diagnosis Related Group SOI into mild/moderate, major, and extreme subgroups. RESULTS: Overall in-hospital mortality was 2.96% (n=399); in-hospital mortality for the ≥80-year-old group (n=139, 4.78%) was significantly higher than the 20- to 49-year-old (n=9, 0.84%, P<0.001) or 50- to 79-year-old (n=251, 2.64%, P<0.001) groups. In-hospital mortality was significantly higher in the extreme SOI group (n=296, 15.33%) than in the minor/moderate (n=22, 0.35%, P<0.001) and major SOI groups (n=81, 1.51%, P<0.001). Median in-hospital costs in the mild/moderate, major, and extreme SOI strata were $29,202.08, $36,035.13, and $57,572.92, respectively. CONCLUSION: In the minor, moderate, and major SOI groups, in-hospital mortality and costs are low regardless of age; these groups represent >85% of patients undergoing isolated AVR for aortic stenosis. Conversely, in patients classified as having extreme SOI, surgical therapy is associated with exceedingly high inpatient mortality, low home discharge rates, and high resource utilization, particularly in the advanced age group.

11.
J Acoust Soc Am ; 136(3): 1013, 2014 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-25190377

RESUMEN

The accuracy of outdoor sound propagation predictions is often limited by imperfect knowledge of the atmospheric and ground properties, and random environmental variations such as turbulence. This article describes the impact of such uncertainties, and how they can be efficiently addressed and quantified with stochastic sampling techniques such as Monte Carlo and Latin hypercube sampling (LHS). Extensions to these techniques, such as importance sampling based on simpler, more efficient propagation models, and adaptive importance sampling, are described. A relatively simple example problem involving the Lloyd's mirror effect for an elevated sound source in a homogeneous atmosphere is considered first, followed by a more complicated example involving near-ground sound propagation with refraction and scattering by turbulence. When uncertainties in the atmospheric and ground properties dominate, LHS with importance sampling is found to converge to an accurate estimate with the fewest samples. When random turbulent scattering dominates, the sampling method has little impact. A comprehensive computational approach is demonstrated that is both efficient and accurate, while simultaneously incorporating broadband sources, turbulent scattering, and uncertainty in the environmental properties.

12.
Public Health Res Pract ; 25(1)2014 Nov 28.
Artículo en Inglés | MEDLINE | ID: mdl-25828444

RESUMEN

AIM: Liveable communities create the conditions to optimise health and wellbeing outcomes in residents by influencing various social determinants of health - for example, neighbourhood walkability and access to public transport, public open space, local amenities, and social and community facilities. This study will develop national liveability indicators that are (a) aligned with state and federal urban policy, (b) developed using national data (where available), (c) standard and consistent over time, (d) suitable for monitoring progress towards creating more liveable, equitable and sustainable communities, (e) validated against selected noncommunicable disease risk behaviours and/or health outcomes, and (f) practical for measuring local, national and federal built environment interventions. STUDY TYPE: Protocol. METHOD: Over two years, the National Liveability Study, funded through The Australian Prevention Partnership Centre (TAPPC), will develop and validate a national set of spatially derived built environment liveability indicators related to noncommunicable disease risk behaviours and/or health outcomes, informed by a review of relevant policies in selected Australian state and territory governments. To create national indicators, we will compare measures developed using national data with finer-grained state-level data, which have been validated against a range of outcomes. Finally, we will explore the creation of a national database of built environment spatial indicators. RESULTS: A national advisory group comprising stakeholders in state and federal government, federal nongovernment organisations and state-based technical working groups located in the ACT, Victoria, NSW, Queensland and WA has been established; a policy analysis is under way and work programs are being prepared. CONCLUSION: This project seeks to build the capacity for built environment and health systems research by developing national indicators to monitor progress towards creating healthy and liveable communities. This ambition requires multisector engagement and an interdisciplinary research team.


Asunto(s)
Enfermedad Crónica/prevención & control , Planificación de Ciudades/normas , Planificación Ambiental/normas , Conductas Relacionadas con la Salud , Promoción de la Salud/normas , Determinantes Sociales de la Salud , Australia , Ciclismo , Promoción de la Salud/métodos , Humanos , Evaluación de Programas y Proyectos de Salud/métodos , Evaluación de Programas y Proyectos de Salud/normas , Conducta de Reducción del Riesgo , Seguridad/normas , Transportes/métodos , Transportes/normas , Caminata
13.
J Acoust Soc Am ; 133(3): EL195-201, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23464128

RESUMEN

Statistical evidence for various models relating day-night sound level (DNL) to community noise annoyance is assessed with the Akaike information criterion. In particular, community-specific adjustments such as the community tolerance level (CTL, the DNL at which 50% of survey respondents are highly annoyed) and community tolerance spread (CTS, the difference between the DNL at which 90% and 10% are highly annoyed) are considered. The results strongly support models characterizing annoyance on a community-by-community basis, rather than with complete pooling and analysis of all available surveys. The most likely model was found to be a 2-parameter logistic model, with CTL and CTS fit independently to survey data from each community.


Asunto(s)
Aeronaves , Percepción Auditiva , Exposición a Riesgos Ambientales , Genio Irritable , Modelos Logísticos , Ruido del Transporte/efectos adversos , Actitud , Monitoreo del Ambiente , Humanos , Modelos Lineales , Características de la Residencia , Factores de Tiempo
14.
J Acoust Soc Am ; 122(3): 1374, 2007 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-17927400

RESUMEN

Outdoor sound propagation predictions are compromised by uncertainty and error in the atmosphere and terrain representations, and sometimes also by simplified or incorrect physics. A model's predictive power, i.e., its accurate representation of the sound propagation, cannot be assessed without first quantifying the ensemble sound pressure variability and sensitivity to uncertainties in the model's governing parameters. This paper describes fundamental steps toward this goal for a single-frequency point source. The atmospheric surface layer is represented through Monin-Obukhov similarity theory and the acoustic ground properties with a relaxation model. Sound propagation is predicted with the parabolic equation method. Governing parameters are modeled as independent random variables across physically reasonable ranges. Latin hypercube sampling and proper orthogonal decomposition (POD) are employed in conjunction with cluster-weighted models to develop compact representations of the sound pressure random field. Full-field sensitivity of the sound pressure field is computed via the sensitivities of the POD mode coefficients to the system parameters. Ensemble statistics of the full-field sensitivities are computed to illustrate their relative importance at every down range location. The central role of sensitivity analysis in uncertainty quantification of outdoor sound propagation is discussed and pitfalls of sampling-based sensitivity analysis for outdoor sound propagation are described.


Asunto(s)
Atmósfera , Sonido , Modelos Biológicos , Modelos Teóricos , Presión , Reproducibilidad de los Resultados , Sensibilidad y Especificidad , Espectrografía del Sonido
15.
J Acoust Soc Am ; 121(5 Pt1): EL177-83, 2007 May.
Artículo en Inglés | MEDLINE | ID: mdl-17550200

RESUMEN

Predictive skill for outdoor sound propagation is assessed using high-resolution atmospheric fields from large-eddy simulations (LES). Propagation calculations through the full LES fields are compared to calculations through subsets of the LES fields that have been processed in typical ways, such as mean vertical profiles and instantaneous vertical profiles synchronized to the sound propagation. It is found that mean sound pressure levels can be predicted with low errors from the mean profiles, except in refractive shadow regions. Prediction of sound pressure levels for short-duration events is much less accurate, with errors of 8 -10 dB for near-ground propagation being typical.


Asunto(s)
Ambiente , Movimiento (Física) , Sonido , Atmósfera , Modelos Estadísticos , Valor Predictivo de las Pruebas , Viento
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