Impacto de la pandemia por COVID-19 en un programa de cirugía cardiovascular pediátrica de un hospital público de Argentina / Impact of the COVID-19 pandemic on a pediatric cardiovascular surgery program of a public hospital from Argentina

Objetivo. Describir el impacto de la pandemia por COVID-19 en el programa de cirugía cardiovascular pediátrica y estimar el tiempo para reducir la lista de espera quirúrgica. Métodos. Estudio descriptivo y retrospectivo. Se compararon resultados quirúrgicos del período preCOVID versus el período COVID. Se utilizó un modelo matemático para estimar el tiempo para reducir la lista de espera. Resultados. Entre el 23 de marzo y el 31 de agosto de 2020 se operaron 83 pacientes, que representan una reducción del 60 %, respecto al período preCOVID. La mediana de edad fue de 6 meses (rango intercuartílico [RIC]: 25-75, 1,8 meses a 2,9 años; p = 0,0023. El tiempo para eliminar la lista de espera varía entre 10 y 19 meses. Conclusiones. El programa tuvo una reducción del 60 %. El tiempo de resolución de la lista de espera puede ser al menos 10 a 19 meses

Objective. To describe the impact of the COVID-19 pandemic on a pediatric cardiovascular surgery program and estimate the necessary time to reduce the surgery waiting list. Methods. Retrospective, descriptive study. Surgical outcomes from the pre-COVID-19 period and COVID-19 period were compared. A mathematical model was used to estimate the time necessary to reduce the waiting list. Results. Between March 23rd and August 31st, 2020, 83 patients underwent surgery, accounting for a 60 % reduction compared to the pre-COVID-19 period. Their median age was 6 months (interquartile range [IQR]: 25-75, 1.8 months to 2.9 years; p = 0.0023). The time necessary to eliminate the waiting list ranges from 10 to 19 months. Conclusions. There was a 60 % reduction in the program. The time required to clear the backlog of cases may range from, at least, 10 to 19 month

Impact of the COVID-19 pandemic on a pediatric cardiovascular surgery program of a public hospital from Argentina. / Impacto de la pandemia por COVID-19 en un programa de cirugía cardiovascular pediátrica de un hospital público de Argentina.

OBJECTIVE: To describe the impact of the COVID-19 pandemic on a pediatric cardiovascular surgery program and estimate the necessary time to reduce the surgery waiting list. METHODS: Retrospective, descriptive study. Surgical outcomes from the pre-COVID-19 period and COVID-19 period were compared. A mathematical model was used to estimate the time necessary to reduce the waiting list. RESULTS: Between March 23rd and August 31st, 2020, 83 patients underwent surgery, accounting for a 60 % reduction compared to the pre-COVID-19 period. Their median age was 6 months (interquartile range [IQR]: 25-75, 1.8 months to 2.9 years; p = 0.0023). The time necessary to eliminate the waiting list ranges from 10 to 19 months. CONCLUSIONS: There was a 60 % reduction in the program. The time required to clear the backlog of cases may range from, at least, 10 to 19 months.

Objetivo. Describir el impacto de la pandemia por COVID-19 en el programa de cirugía cardiovascular pediátrica y estimar el tiempo para reducir la lista de espera quirúrgica. Métodos. Estudio descriptivo y retrospectivo. Se compararon resultados quirúrgicos del período preCOVID versus el período COVID. Se utilizó un modelo matemático para estimar el tiempo para reducir la lista de espera. Resultados. Entre el 23 de marzo y el 31 de agosto de 2020 se operaron 83 pacientes, que representan una reducción del 60 %, respecto al período preCOVID. La mediana de edad fue de 6 meses (rango intercuartílico [RIC]: 25-75, 1,8 meses a 2,9 años; p = 0,0023. El tiempo para eliminar la lista de espera varía entre 10 y 19 meses. Conclusiones. El programa tuvo una reducción del 60 %. El tiempo de resolución de la lista de espera puede ser al menos 10 a 19 meses.

Asistencia con membrana de oxigenación extracorpórea en recuperación cardiovascular pediátrica: experiencia de un centro de Argentina / Extracorporeal membrane oxygenation in pediatric cardiovascular care: Experience of a center in Argentina

Objetivo: Describir resultados de membrana de oxigenación extracorpórea en pacientes con cirugía cardíaca y analizar los factores de riesgos de morbimortalidad. Métodos: Estudio retrospectivo, de pacientes cardíacos con asistencia circulatoria. Se registraron variables, diagnóstico, cirugía, puntaje Risk Adjustment for Congenital Heart Surgery (RACHS), momento de colocación, canulación, días de asistencia en internación, complicaciones, sobrevida y seguimiento. Se analizaron los riesgos edad, peso, RACHS, patología uni- o biventricular, momento de colocación, días de asistencia e internación, y complicaciones. Análisis estadístico descriptivo y de regresión logística para factores de riesgo. Resultados: En 5295 admisiones, 72 pacientes requirieron membrana de oxigenación extracorpórea (1,37 %). Edad mediana: 6,5 meses (rango intercuartilo -RIQ-: 20 días-2 años); peso: 5,5 kg (RIQ: 3,25-9,5); tiempo de bomba: 188 min (RIQ: 134-246,5); de clampeo: 92 min (65-117). La canulación fue en quirófano en 34 casos (47 %). La mediana de asistencia fue 3 días (RIQ: 2-5), y de internación, 20 (RIQ: 11-32). La sobrevida al alta fue 49 %; 8 pacientes fallecieron durante el seguimiento. La complicación más frecuente fue hemorragia ( 57 %). El peso <5 kg (p = 0,01) y vasopresores en asistencia (p = 0,012) tuvieron riesgo de mortalidad. La sobrevida a 10 años fue del 77 %, con 84 % en clase funcional 1-2 y el 37 % presentaba algún grado de retardo madurativo. Conclusiones: La complicación más frecuente fue la hemorragia; peso y vasopresores se asociaron con mortalidad.

Objective: To describe the results of extracorporeal membrane oxygenation in patients undergoing heart surgery and analyze the risk factors for morbidity and mortality. Methods: Retrospective study conducted in cardiac patients under circulatory support. Outcome measures, diagnosis, surgery, Risk Adjustment for Congenital Heart Surgery (RACHS) score, implantation time, cannulation, length of support during stay, complications, survival, and follow-up were recorded. Risks were analyzed in relation to age, weight, RACHS score, single-ventricle or biventricular disease, implantation time, length of support and stay, and complications. Descriptive statistical and logistic regression analyses for risk factors were done. Results: Among 5295 hospitalizations, 72patients required extracorporeal membrane oxygenation (1.37 %). Median age: 6.5 months (interquartile range [IQR]: 20 days-2 years); weight: 5.5 kg (IQR: 3.25-9.5); pump time: 188 min (IQR: 134- 246.5); clamp time: 92 min (65-117). Cannulation was done in the operating room in 34 cases (47 %). The median length of support was 3 days (IQR: 2-5), and of stay, 20 days (IQR: 11-32). Survival at discharge was 49 %; 8 patients died during follow-up. The most common complication was bleeding (57 %). Weight<5 kg (p = 0.01) and vasopressor use during support (p = 0.012) were associated with a risk for mortality. The survival rate at 10 years was 77 %; 84% of patients corresponded to functional class 1-2, and 37% had some degree of developmental delay.

Extracorporeal membrane oxygenation in pediatric cardiovascular care: Experience of a center in Argentina. / Asistencia con membrana de oxigenación extracorpórea en recuperación cardiovascular pediátrica: experiencia de un centro de Argentina.

Objective: To describe the results of extracorporeal membrane oxygenation in patients undergoing heart surgery and analyze the risk factors for morbidity and mortality. Methods: Retrospective study conducted in cardiac patients under circulatory support. Outcome measures, diagnosis, surgery, Risk Adjustment for Congenital Heart Surgery (RACHS) score, implantation time, cannulation, length of support during stay, complications, survival, and follow-up were recorded. Risks were analyzed in relation to age, weight, RACHS score, single-ventricle or biventricular disease, implantation time, length of support and stay, and complications. Descriptive statistical and logistic regression analyses for risk factors were done. Results: Among 5295hospitalizations, 72 patients required extracorporeal membrane oxygenation (1.37 %). Median age: 6.5 months (interquartile range [IQR]: 20 days-2 years); weight: 5.5 kg (IQR: 3.25-9.5); pump time: 188 min (IQR: 134246.5); clamp time: 92 min (65-117). Cannulation was done in the operating room in 34 cases (47 %). The median length of support was 3 days (IQR: 2-5), and of stay, 20 days (IQR: 1132). Survival at discharge was 49 %; 8 patients died during follow-up. The most common complication was bleeding (57 %). Weight < 5 kg (p = 0.01) and vasopressor use during support (p = 0.012) were associated with a risk for mortality. The survival rate at 10 years was 77 %; 84 % of patients corresponded to functional class 1-2, and 37 % had some degree of developmental delay. Conclusions: The most common complication was bleeding; weight and vasopressor use were associated with mortality.

Objetivo: Describir resultados de membrana de oxigenación extracorpórea en pacientes con cirugía cardíaca y analizar los factores de riesgos de morbimortalidad. Métodos: Estudio retrospectivo, de pacientes cardíacos con asistencia circulatoria. Se registraron variables, diagnóstico, cirugía, puntaje Risk Adjustment for Congenital Heart Surgery (RACHS), momento de colocación, canulación, días de asistencia en internación, complicaciones, sobrevida y seguimiento. Se analizaron los riesgos edad, peso, RACHS, patología uni- o biventricular, momento de colocación, días de asistencia e internación, y complicaciones. Análisis estadístico descriptivo y de regresión logística para factores de riesgo. Resultados: En 5295 admisiones, 72 pacientes requirieron membrana de oxigenación extracorpórea (1,37 %). Edad mediana: 6,5 meses (rango intercuartilo -RIQ-: 20 días-2 años); peso: 5,5 kg (RIQ: 3,25-9,5); tiempo de bomba: 188 min (RIQ: 134-246,5); de clampeo: 92 min (65-117). La canulación fue en quirófano en 34 casos (47 %). La mediana de asistencia fue 3 días (RIQ: 2-5), y de internación, 20 (RIQ: 11-32). La sobrevida al alta fue 49 %; 8 pacientes fallecieron durante el seguimiento. La complicación más frecuente fue hemorragia ( 57 %). El peso <5 kg (p = 0,01) y vasopresores en asistencia (p = 0,012) tuvieron riesgo de mortalidad. La sobrevida a 10 años fue del 77 %, con 84 % en clase funcional 1-2 y el 37 % presentaba algún grado de retardo madurativo. Conclusiones: La complicación más frecuente fue la hemorragia; peso y vasopresores se asociaron con mortalidad.

Morbilidad en cirugía de cardiopatìa congénita en un hospital público en Argentina / Morbidity in congenital heart surgery in a public hospital in Argentina

Objetivo: Describir las complicaciones asociadas a cirugía cardíaca, compararlas con una población de referencia e identificar factores de riesgo de mortalidad. Pacientes y métodos: Estudio retrospectivo, descriptivo. Se incluyeron todos los pacientes operados en 2013-2015 en el Hospital Garrahan. Se registró edad, peso, procedimiento, ventilación mecánica, días de internación, morbilidad y evolución. Se consideró morbilidad la insuficiencia renal con diálisis, déficit neurológico, marcapaso permanente, asistencia circulatoria, parálisis frénica o de cuerdas vocales, reoperación, infección de herida, quilotórax y traqueotomía. Se realizó un análisis estadístico descriptivo y por categorías de riesgo utilizando la escala de morbilidad de la Sociedad de Cirugía Torácica (Surgical Thoracic Society, STS). Resultados: 1536 pacientes, mediana de 12 meses (rango intercuartílico -RIC- 25-75: 3-60), peso de 8 kg (RIC25-75: de 4,4 a 17,5), con mortalidad de 5%. Se registraron 361 eventos en 183 pacientes. La reoperación no planificada fue el más frecuente (7,2%); los restantes ocurrieron en ≤ 3% de los pacientes. En comparación con los pacientes sin complicaciones, los pacientes con eventos tuvieron más días de ventilación mecánica: 9,95 (RIC25-75: 7,65-12,24) vs. 1,8 (RIC25- 75: 1,46-2,14), p< 0,00001; mayor internación: 28,8 (RIC25-75: 25,1-32,5) vs. 8,5 (RIC25-75: 7,99,2), p <0,0001; y mayor mortalidad: 19,6% vs. 3,1%(RR 4,58;IC95%: de 3,4 a 6,0), p <0,0001. La asistencia circulatoria e insuficiencia renal se asociaron con mayor mortalidad. Conclusiones: La reoperación no planificada fue el evento más frecuente. Los pacientes con complicaciones tuvieron más días de ventilación mecánica, de internación y mayor mortalidad. La asistencia circulatoria y la insuficiencia renal se asociaron con mayor mortalidad.

Objective: To describe the complications associated with heart surgery, compare them to a reference population, and identify mortality risk factors. Patients and methods: Retrospective and descriptive study. All patients who underwent surgery at Hospital Garrahan in the 2013-2015 period were included. Age, weight, procedure, mechanical ventilation, length of stay in days, morbidity, and course were recorded. Renal failure requiring dialysis, neurological deficit, permanent pacemaker, circulatory support, phrenic nerve or vocal cord palsy, reoperation, wound infection, chylothorax, and tracheotomy were considered morbidities. A descriptive, statistical analysis by risk category was done using the Society of Thoracic Surgeons (STS) morbidity score. Results: 1536 patients, median age: 12 months (interquartile range --#91;IQR--#93; 25-75: 3-60), weight: 8 kg (IQR 25-75: 4.4 to 17.5), mortality: 5%. A total of 361 events were recorded in 183 patients. An unplanned reoperation was the most common event (7.2%); the rest occurred in < 3% of patients. Compared to patients without complications, patients who had events required more days on mechanical ventilation: 9.95 (IQR 25-75: 7.6512.24) versus 1.8 (IQR 2575: 1.46-2.14), p< 0.00001; a longer length of stay: 28.8 (IQR 25-75: 25.1-32.5) versus 8.5 (IQR 25-75: 7.9-9.2), p< 0.0001; and had a higher mortality: 19.6% versus 3.1% (RR: 4.58, 95% CI: 3.4 to 6.0), p< 0.0001. Circulatory support and renal failure were associated with a higher mortality. Conclusions: An unplanned reoperation was the most common event. Patients with complications required more days on mechanical ventilation and a longer length of stay and had a higher mortality. Circulatory support and renal failure were associated with a higher mortality.

Morbidity in congenital heart surgery in a public hospital in Argentina. / Morbilidad en cirugía de cardiopatìa congénita en un hospital público en Argentina.

OBJECTIVE: To describe the complications associated with heart surgery, compare them to a reference population, and identify mortality risk factors. PATIENTS AND METHODS: Retrospective and descriptive study. All patients who underwent surgery at Hospital Garrahan in the 2013-2015 period were included. Age, weight, procedure, mechanical ventilation, length of stay in days, morbidity, and course were recorded. Renal failure requiring dialysis, neurological deficit, permanent pacemaker, circulatory support, phrenic nerve or vocal cord palsy, reoperation, wound infection, chylothorax, and tracheotomy were considered morbidities. A descriptive, statistical analysis by risk category was done using the Society of Thoracic Surgeons (STS) morbidity score. RESULTS: 1536 patients, median age: 12 months (interquartile range [IQR] 25-75: 3-60), weight: 8 kg (IQR 25-75: 4.4 to 17.5), mortality: 5%. A total of 361 events were recorded in 183 patients. An unplanned reoperation was the most common event (7.2%); the rest occurred in < 3% of patients. Compared to patients without complications, patients who had events required more days on mechanical ventilation: 9.95 (IQR 25-75: 7.6512.24) versus 1.8 (IQR 2575: 1.46-2.14), p< 0.00001; a longer length of stay: 28.8 (IQR 25-75: 25.1-32.5) versus 8.5 (IQR 25-75: 7.9-9.2), p< 0.0001; and had a higher mortality: 19.6% versus 3.1% (RR: 4.58, 95% CI: 3.4 to 6.0), p< 0.0001. Circulatory support and renal failure were associated with a higher mortality. CONCLUSIONS: An unplanned reoperation was the most common event. Patients with complications required more days on mechanical ventilation and a longer length of stay and had a higher mortality. Circulatory support and renal failure were associated with a higher mortality.

OBJETIVO: Describir las complicaciones asociadas a cirugía cardíaca, compararlas con una población de referencia e identificar factores de riesgo de mortalidad. PACIENTES Y MÉTODOS: Estudio retrospectivo, descriptivo. Se incluyeron todos los pacientes operados en 2013-2015 en el Hospital Garrahan. Se registró edad, peso, procedimiento, ventilación mecánica, días de internación, morbilidad y evolución. Se consideró morbilidad la insuficiencia renal con diálisis, déficit neurológico, marcapaso permanente, asistencia circulatoria, parálisis frénica o de cuerdas vocales, reoperación, infección de herida, quilotórax y traqueotomía. Se realizó un análisis estadístico descriptivo y por categorías de riesgo utilizando la escala de morbilidad de la Sociedad de Cirugía Torácica (Surgical Thoracic Society, STS). RESULTADOS: 1536 pacientes, mediana de 12 meses (rango intercuartílico -RIC- 25-75: 3-60), peso de 8 kg (RIC25-75: de 4,4 a 17,5), con mortalidad de 5%. Se registraron 361 eventos en 183 pacientes. La reoperación no planificada fue el más frecuente (7,2%); los restantes ocurrieron en ≤ 3% de los pacientes. En comparación con los pacientes sin complicaciones, los pacientes con eventos tuvieron más días de ventilación mecánica: 9,95 (RIC25-75: 7,65-12,24) vs. 1,8 (RIC25- 75: 1,46-2,14), p< 0,00001; mayor internación: 28,8 (RIC25-75: 25,1-32,5) vs. 8,5 (RIC25-75: 7,99,2), p <0,0001; y mayor mortalidad: 19,6% vs. 3,1%(RR 4,58;IC95%: de 3,4 a 6,0), p <0,0001. La asistencia circulatoria e insuficiencia renal se asociaron con mayor mortalidad. CONCLUSIONES: La reoperación no planificada fue el evento más frecuente. Los pacientes con complicaciones tuvieron más días de ventilación mecánica, de internación y mayor mortalidad. La asistencia circulatoria y la insuficiencia renal se asociaron con mayor mortalidad.

[Congenital heart disease: surgical results in a public hospital in Argentina]. / Cardiopatías congénitas: resultados quirúrgicos en un hospital público en Argentina.

OBJECTIVE: To describe the results of congenital heart surgery at the Hospital de Pediatría J. P.Garrahan. METHODS: Between 2004 and 2009, 2942 patients, median age 2.5 years (1 d to 22.5 y), median weight 11.5 kg (1.6 kg to 96 kg), and 84% with cardiopulmonary bypass, were analyzed. Adjusted mortality risk analysis using RACHS and Aristotle score was performed. Newborn surgery and one stage repair in Fallot and ventricular septal defect with coarctation were analyzed as subgroupes. RESULTS: Mortality was 5.5%. Required mechanical ventilation 45%, 5% peritoneal dialysis, 12% delayed sternal closure and 8.4% reoperation. Twenty five percent with previous surgery, and 10% in poor clinical conditions. RACHS-1 categories morality distribution were 0.4% in one, 2.4% in two, 7.1% in three, 14% in four y 34 % in 5 and 6. One stage repair was performed in 84% of Fallots and 90% of ventricular septal defects with coarctation, with 3.2% and 10% mortality rate respectively. Two hundred and five newborns were operated with cardiopulmonary bypass with a mortality rate of 15% in the last year. CONCLUSIONS: Almost every congenital heart disease can be repaired without previous palliation, with satisfactory results in our institution. Poor clinical conditions significantly increased morbidity and mortality.

Cardiopatías congénitas: resultados quirúrgicos en un hospital público en Argentina / Congenital heart disease: surgical results in a public hospital in Argentina

Objetivo: Describir los resultados en cirugía cardiovascular del Hospital de Pediatría J. P. Garrahan. Métodos: Se analizaron 2942 pacientes entre 2004 y 2009; de los cuales, 84% con circulación extracorpórea, mediana de edad 2.5 años, rango de un día a 22.5 años y peso 11.5 kg (1.6 kg a 96 kg); con cirugías previas 25% y 10% malas condiciones preoperatorias. Se analizó la mortalidad por RACHS-1 y Aristóteles, la cirugía neonatal, la cirugía en un tiempo de Fallot y de comunicación interventricular con coartación de aorta. Resultados: La mortalidad fue 5.5%. Requirió ventilación mecánica 45%, 5% diálisis peritoneal, 12% cierre esternal diferido y 8.4% reoperación. De los Fallot 84% y 90% de las comunicaciones interventriculares con coartación se repararon en un tiempo, con 3.2% y 10% de mortalidad respectivamente. Se operaron 205 neonatos con bomba y con 15% de mortalidad en el último año. Las malas condiciones previas aumentaron la morbilidad, (Odds ratio 3.63 IC 95%, 2.27 -4.81) y la mortalidad (Odds ratio 6.47 IC 95%, 4.36 - 9.60). La mortalidad por RACHS fue 0.4% en categoría uno, 2.4% en la dos, 7.1% en la tres, 14% en la cuatro y 34% en la cinco y seis. Conclusiones: En nuestra institución la mayoría de las cardiopatías se resuelven en un tiempo con resultados satisfactorios. Las malas condiciones preoperatorias aumentan significativamente la morbimortalidad.

Objective: To describe the results of congenital heart surgery at the Hospital de Pediatría J. P.Garrahan. Methods: Between 2004 and 2009, 2942 patients, median age 2.5 years (1 d to 22.5 y), median weight 11.5 kg (1.6 kg to 96 kg), and 84% with cardiopulmonary bypass, were analyzed. Adjusted mortality risk analysis using RACHS and Aristotle score was performed. Newborn surgery and one stage repair in Fallot and ventricular septal defect with coarctation were analyzed as subgroupes. Results: Mortality was 5.5%. Required mechanical ventilation 45%, 5% peritoneal dialysis, 12% delayed sternal closure and 8.4% reoperation. Twenty five percent with previous surgery, and 10% in poor clinical conditions. RACHS-1 categories morality distribution were 0.4% in one, 2.4% in two, 7.1% in three, 14% in four y 34 % in 5 and 6. One stage repair was performed in 84% of Fallots and 90% of ventricular septal defects with coarctation, with 3.2% and 10% mortality rate respectively. Two hundred and five newborns were operated with cardiopulmonary bypass with a mortality rate of 15% in the last year. Conclusions: Almost every congenital heart disease can be repaired without previous palliation, with satisfactory results in our institution. Poor clinical conditions significantly increased morbidity and mortality.

Clinical experience with Berlin Heart Excor in pediatric patients in Argentina: 1373 days of cardiac support.

The objective of this study was to describe our experience (1373 days of support) with the Berlin Heart Excor (BH) ventricular-assist device (VAD) as bridging to cardiac transplantation in pediatric patients with end-stage cardiomyopathy. This study involved a retrospective observational cohort. Records of patients supported with the BH VAD were reviewed. Data regarding age, sex, weight, diagnosis, preoperative condition, single versus biventricular support, morbidity, and mortality were collected. Criteria for single versus biventricular support and intensive care unit management were registered. The procedure was approved by our Institutional Ethics Committee, and informed consent was obtained. Between March 2006 and March 2010, 12 patients with diagnosis of dilated (n = 10) and restrictive (n = 2) cardiomyopathy were supported. Median age was 56.6 months (range 20.1-165.9); mean weight was 18.3 kg (range 8.5-45); and nine patients were female. Every patient presented with severe heart failure refractory to pharmacological therapy. Biventricular support was necessary in four patients. Nine patients underwent heart transplantation. No child was weaned off the BH VAD because of myocardial recovery. Mean length of support was 73 days (range 3-331), and the total number of days of support was 1373. Three patients had fatal complications: 2 had thrombo-hemorrhagic stroke leading to brain death, and one had refractory vasoplegic shock. The BH VAD is a useful and reasonable safe device for cardiac transplantation bridging in children with end-stage heart failure. Team experience resulted in less morbidity and mortality, and time for implantation, surgical procedure, anticoagulation monitoring, and patient care improved.

[Cardiac surgical repair in newborns: five years' experience in neonatal open surgery]. / Cirugía cardíaca reparadora en recién nacidos: experiencia de 5 años en cirugía neonatal con circulación extracorpórea.

INTRODUCTION: Four hundred newborns die every year in our country suffering from congenital heart disease. Definitive surgical repair, whenever possible, is nowadays the optimal therapeutic strategy. Our goal is to describe mortality and morbidity in neonatal surgery with cardiopulmonary bypass in a tertiary public hospital in Argentina. PATIENTS AND METHODS: Descriptive, retrospective study. Every patient, younger than 45 days, with cardiac surgery requiring cardiopulmonary bypass, at the Garrahan Hospital between 2004 and 2008 was included. Demographic, surgical and postoperative data were collected. Adjusted mortality risk analysis, and descriptive statistics from the most frequent diagnosis were performed. Results are expressed as median and rank or percentage. RESULTS: 200 newborns were operated, 62% males. Median age was 21 days (r 1- 45) and median weight 3.1 kg (r 1.6-6.2). Total anomalous pulmonary venous return, transposition of great arteries an hypoplastic left heart syndrome diagnoses accounted for 75% of the procedures. Median length of stay was 12 days (r 0-191), and 6 days of mechanical ventilation (r 0-180). Eighteen percent of the patients required peritoneal dialysis. Whole series mortality was 19% and fell to 14% in 2008. Unstable preoperative condition and postoperative complications increased mortality, OR= 2.23 (1.02-4.89) and OR= 10 (3.6-33.4), respectively. CONCLUSIONS: Our postoperative mortality is similar to those reported in foreign countries databases. Patients with unstable preoperative condition and post-operative complications had higher mortality.

Cirugía cardíaca reparadora en recién nacidos: experiencia de 5 años en cirugía neonatal con circulación extracorpórea / Cardiac surgical repair in newborns: five years experience in neonatal open surgery

Introducción. En nuestro país fallecen anualmente 400 niños con cardiopatía congénita, en el 1er mes de vida. La cirugía constituye la estrategia actual para su tratamiento. El objetivo es describir la mortalidad hospitalaria y las complicaciones de la cirugía cardíaca neonatal con circulación extracorpórea en un hospital público de alta complejidad. Pacientes y métodos. Estudio descriptivo retrospectivo. Se registraron datos demográficos, de la cirugía y del postoperatorio de los pacientes con circulación extracorpórea, menores de 45 días, operados en el Hospital Garrahan, entre 2004-2008. Se realizó un análisis por patologías y de mortalidad ajustado por riesgo. Los resultados se expresan en mediana e intervalo, o en porcentaje, según corresponda. Resultados. Se operaron 200 recién nacidos, 62 por ciento varones. La edad fue 21 (1- 45) días y el peso 3,1 (1,6-6,2) kg. Anomalía total de retorno venoso pulmonar, transposición de grandes arterias y síndrome de corazón izquierdo hipoplásico concentraronel 75 por ciento de las cirugías. El tiempo de internación fue 12 (0-191) días, con 6 (0-180) días de ventilación mecánica, y 18 por ciento de los pacientes requirieron diálisis. La mortalidad global fue 19 por ciento y 14 por ciento en el último año analizado. Los pacientes en mala condición preoperatoria, así como los que presentaron complicaciones, exhibieron una mortalidad mayor (OR= 2,23 [1,02-4,89] y OR= 10 [3,6-33,4], respectivamente). Conclusiones. La mortalidad postoperatoria es similar a la comunicada en bases de datos del exterior. Los pacientes con mala condición preoperatoria y aquellos con complicaciones presentaron mayor mortalidad en nuestra serie.

Introduction. Four hundred newborns die every year in our country suffering from congenital heart disease. Definitive surgical repair, whenever possible, is nowadays the optimal therapeutic strategy. Our goal is to describe mortality and morbidity in neonatal surgery with cardiopulmonary bypass in a tertiary public hospital in Argentina. Patients and methods. Descriptive, retrospective study. Every patient, younger than 45 days, with cardiac surgery requiring cardiopulmonary bypass, at the Garrahan Hospital between 2004 and 2008 was included. Demographic, surgical and postoperative data were collected. Adjusted mortality risk analysis, and descriptive statistics from the most frequent diagnosis were performed. Results are expressed as median and rank or percentage. Results. 200 newborns were operated, 62 percent males. Median age was 21 days (r 1- 45) and median weight 3.1 kg (r 1.6-6.2). Total anomalous pulmonary venous return, transposition of great arteries and hypoplastic left heart syndrome diagnoses accounted for 75 percent of the procedures. Median length of stay was 12 days (r 0-191), and 6 days of mechanical ventilation (r 0-180). Eighteen percent of the patients required peritoneal dialysis. Whole series mortality was 19 percent and fell to 14 pecent in 2008. Unstable preoperative condition and postoperative complications increased mortality, OR= 2.23 (1.02-4.89) and OR= 10 (3.6-33.4), respectively. Conclusions. Our postoperative mortality is similar to those reported in foreign countries databases. Patients with unstable preoperative condition and post-operative complications had higher mortality.