How task-unrelated and freely moving thought relate to affect: Evidence for dissociable patterns in everyday life.

Much of our knowledge about the correlates of mind-wandering comes from assessing task-unrelated thought. Less is known about the correlates of freely moving thought, a dimension that assesses the degree to which thoughts arise and unfold with low levels of guidance or constraints. Task-unrelated thought is consistently associated with more negative affective valence compared with being on task; however, it is unclear whether freely moving thought shares the same relationship with affect. We conducted two ecological momentary assessment studies in the context of everyday life and found that the two dimensions have different affective correlates. In Study 1, task-unrelated thought was associated with less positive concurrent valence than being on-task. However, freely moving thought was associated with more positive concurrent valence and was predictive of more positive valence at a subsequent timepoint. Freely moving thought, but not task-unrelated thought, also positively predicted concurrent arousal. Computational sentiment analyses of participants' thought descriptions offered convergent evidence of differential relationships between the two thought dimensions and affect. Study 2 used different measurement scales to assess whether (a) the pattern of findings replicated and (b) if the effects were robust to changes in measurement. The main findings were replicated: task-unrelated thought was negatively associated with concurrent valence, whereas freely moving thought was positively associated with concurrent valence. However, freely moving thought did not predict subsequent valence and was not related to concurrent arousal. The most robust findings related to concurrent valence. Although mind-wandering has acquired a relatively negative reputation to date, our findings suggest that there might be positive aspects that remain unexplored. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Generation of transgenic plants expressing plasma membrane-bound antibodies to the environmental pollutant microcystin-LR.

In this paper we describe the engineering and regeneration of transgenic tobacco plants expressing a recombinant plasma membrane-retained antibody specific to microcystin-LR (MC-LR), the environmental toxin pollutant produced by cyanobacteria. The antibody was created by a genetic fusion of the antigen binding regions of the microcystin-specific single chain antibody, 3A8, with the constant regions from the murine IgG1κ, Guy's 13, including a membrane retention sequence at the C-terminal end of the antibody heavy chain. The antibody produced in the leaves was shown to be functional by binding to MC-LR in an ELISA with antibody yields in transgenic plant leaves reaching a maximum of 1.2 µg g(-1) leaf f.wt (0.005% total soluble protein). Antibody-MC-LR complexes formed in leaves after addition of MC-LR to hydroponic medium around the roots of transgenic plant cultures.

Room temperature ionic liquids containing low water concentrations-a molecular dynamics study.

We have performed classical molecular dynamics to study the properties of a water-miscible and a water-immiscible room-temperature ionic liquid when mixed with small quantities of water. The two ionic liquids consist of the same 1-ethyl-3-methylimidazolium ([EMIM]) cation combined with either the boron tetrafluoride ([BF(4)]) or bis(trifluoromethylsulfonyl)imide ([NTf(2)]) anion. It is found that, in both ionic liquids, water clusters of varying sizes are typically hydrogen bonded to two anions with the cation playing a minor role. We also highlight the difficulties of obtaining dynamic quantities such as self-diffusion coefficients from simulations of such viscous systems.