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Am J Dermatopathol ; 43(12): e137-e140, 2021 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-34231496

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ABSTRACT: The presence of myofibroblast differentiation has been proposed as an invading mechanism in basal cell carcinomas. However, small studies regarding α-smooth muscle actin positivity have led to conflicting results. This review of 100 cases examines the association between α-smooth muscle actin positivity on immunohistochemical studies and the clinical and histopathological characteristics of the tumor, including tumor size, thickness, subtype, topography, ulceration, 5-year recurrence rate, and age at diagnosis.


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Actinas/metabolismo , Biomarcadores de Tumor/metabolismo , Carcinoma Basocelular/patología , Neoplasias Cutáneas/patología , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad
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