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Sci Rep ; 11(1): 22273, 2021 11 15.
Artículo en Inglés | MEDLINE | ID: mdl-34782680

RESUMEN

The distribution of lip, oral cavity, and pharynx (LOCP) cancer mortality rates in small domains (defined as the combination of province, age group, and gender) remains unknown in Spain. As many of the LOCP risk factors are preventable, specific prevention programmes could be implemented but this requires a clear specification of the target population. This paper provides an in-depth description of LOCP mortality rates by province, age group and gender, giving a complete overview of the disease. This study also presents a methodological challenge. As the number of LOCP cancer cases in small domains (province, age groups and gender) is scarce, univariate spatial models do not provide reliable results or are even impossible to fit. In view of the close link between LOCP and lung cancer, we consider analyzing them jointly by using shared component models. These models allow information-borrowing among diseases, ultimately providing the analysis of cancer sites with few cases at a very disaggregated level. Results show that males have higher mortality rates than females and these rates increase with age. Regions located in the north of Spain show the highest LOCP cancer mortality rates.


Asunto(s)
Neoplasias de Cabeza y Cuello/mortalidad , Neoplasias Pulmonares/mortalidad , Anciano , Anciano de 80 o más Años , Algoritmos , Femenino , Geografía Médica , Neoplasias de Cabeza y Cuello/epidemiología , Humanos , Neoplasias de los Labios/epidemiología , Neoplasias de los Labios/mortalidad , Neoplasias Pulmonares/epidemiología , Masculino , Modelos Teóricos , Neoplasias de la Boca/epidemiología , Neoplasias de la Boca/mortalidad , Neoplasias Faríngeas/epidemiología , Neoplasias Faríngeas/mortalidad , Vigilancia de la Población , Factores de Riesgo , España/epidemiología , Análisis Espacial
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