Corrigendum: ADHD Rehabilitation through Video Gaming: A Systematic Review Using PRISMA Guidelines of the Current Findings and the Associated Risk of Bias.

[This corrects the article on p. 151 in vol. 6, PMID: 26557098.].

ADHD Rehabilitation through Video Gaming: A Systematic Review Using PRISMA Guidelines of the Current Findings and the Associated Risk of Bias.

Empirical research studies have highlighted the need to investigate whether video game can be useful as a tool within a neuropsychological rehabilitation program for attention deficit hyperactivity disorder (ADHD) patients. However, little is known about the possible gains that this kind of video game-based interventions can produce and even if these gains can be transferred to real life abilities. The present paper aims to uncover key information related to the use of video game in ADHD neuropsychological rehabilitation/intervention by focusing on its gains and its capability to transfer/generalize these gains to real life situation via a systematic review of the empirical literature. The PRISMA guidelines were adopted. Internet-based bibliographic searches were conducted via seven major electronic databases (i.e., PsycARTICLES, PsycINFO, Web of Science, Core Collection BIOSIS Citation Index, MEDLINE, SciELO Citation Index, and PubMed) to access studies examining the association between video game interventions in ADHD patients and behavioral and cognitive outcomes. A total of 14 empirical studies meeting the inclusion criteria were identified. The studies reported the attention, working memory, and the behavioral aspects as the main target of the intervention. Cognitive and behavioral gains were reported after the video game training (VGT). However, many bias related to the choice of outcome instruments, sampling and blindness of assessors, weaken the results power. Additional researches are important to clarify the effects and stability of the VGT programs, and an important effort should be made to construct better methods to assess improvements on everyday cognitive abilities and real world functioning.

Graph analysis of verbal fluency test discriminate between patients with Alzheimer's disease, mild cognitive impairment and normal elderly controls.

Verbal fluency is the ability to produce a satisfying sequence of spoken words during a given time interval. The core of verbal fluency lies in the capacity to manage the executive aspects of language. The standard scores of the semantic verbal fluency test are broadly used in the neuropsychological assessment of the elderly, and different analytical methods are likely to extract even more information from the data generated in this test. Graph theory, a mathematical approach to analyze relations between items, represents a promising tool to understand a variety of neuropsychological states. This study reports a graph analysis of data generated by the semantic verbal fluency test by cognitively healthy elderly (NC), patients with Mild Cognitive Impairment-subtypes amnestic (aMCI) and amnestic multiple domain (a+mdMCI)-and patients with Alzheimer's disease (AD). Sequences of words were represented as a speech graph in which every word corresponded to a node and temporal links between words were represented by directed edges. To characterize the structure of the data we calculated 13 speech graph attributes (SGA). The individuals were compared when divided in three (NC-MCI-AD) and four (NC-aMCI-a+mdMCI-AD) groups. When the three groups were compared, significant differences were found in the standard measure of correct words produced, and three SGA: diameter, average shortest path, and network density. SGA sorted the elderly groups with good specificity and sensitivity. When the four groups were compared, the groups differed significantly in network density, except between the two MCI subtypes and NC and aMCI. The diameter of the network and the average shortest path were significantly different between the NC and AD, and between aMCI and AD. SGA sorted the elderly in their groups with good specificity and sensitivity, performing better than the standard score of the task. These findings provide support for a new methodological frame to assess the strength of semantic memory through the verbal fluency task, with potential to amplify the predictive power of this test. Graph analysis is likely to become clinically relevant in neurology and psychiatry, and may be particularly useful for the differential diagnosis of the elderly.

Surgical treatment of sleep apnea: association between surgeon/hospital volume with outcomes.

OBJECTIVES/HYPOTHESIS: To identify the association between surgeon/hospital volume with outcomes in surgical treatment for obstructive sleep apnea (OSA) in a nationally representative sample. We hypothesized that surgeons/hospitals with lower patient volumes would have: higher mortality rates, longer hospital length of stay (LOS), and higher postoperative complication rates and hospitalization charges. STUDY DESIGN: Secondary data analysis of the 2007 Nationwide Inpatient Sample database. METHODS: We selected 24,298 adults undergoing OSA surgery. The data analysis included trend test, regression, and multivariate models that were adjusted by demographic and clinical variables. RESULTS: The patients were mostly White (76.43%), male (78.26%), with a mean age of 46 years. Patients treated by surgeons with low volume of procedures (1 procedure/year) had significantly higher mortality rate (odds ratio [OR] 3.05; confidence interval [CI], 1.96-4.77), longer average LOS (increased until 8.16 hours), and higher hospitalization charges (increased up to $1701.75) versus medium- and high-volume surgeons (2-4 procedures/year; greater than/or equal to 5 procedures/year, respectively). Patients treated at hospitals with low volume of procedures (0-5/year) had significantly higher occurrence of oxygen desaturation (OR, 2.12; CI, 1.50-2.99), longer LOS (increased until almost 2 hours) and higher hospitalization charges (at least $951.50 more expensive) versus patients treated at high-volume hospitals (greater than/or equal to 18 procedures/year). CONCLUSION: Our investigation validates the hypothesis that lower volume standards (surgeon/hospital) are associated with increase of LOS following surgery to treat OSA, as well as lower surgeon volume associated with increase of mortality and hospitalization charges and lower hospital volume with occurrence of oxygen desaturation as postoperative complication.

Effects of age and gender on performance on Conners' Continuous Performance Test in Brazilian adolescents

The present study analyzed the effects of age and gender on performance on the Conners' Continuous Performance Test (CCPT II) in a sample of Brazilian adolescents aged 12-17 years. The sample consisted of 480 participants (210 boys) with a mean age of 14.34 years (SD ± 1.61 years) who were representative of the socioeconomic class distribution of the city of São Paulo, Brazil. The participants were prescreened for attention-deficit/hyperactivity disorder. The present results found effects of age and gender that were similar to other Brazilian age groups. Compared with males, female participants presented a lower rate of responding to non-target stimuli (i.e., commission errors), a greater ability to discriminate signals (d'), and fewer impulsive responses (i.e., less perseveration) but longer reaction times (Hit RT and Hit RT Std Error). A significant effect of age was found on RTs (Hit RT, Hit RT Sdt Error, Variability, Hit RT Block Change), commission errors, and perseveration. As age increased, the differences diminished. The present results may be useful for research and clinical studies with Brazilian adolescents.

Focus sustained attention and vigilance: attentional dimensions affected in adolescents with ADHD / Foco, atenção sustentada e vigilância: dimensões atencionais afetadas em adolescentes com TDAH

Objectives: This study performed a statistical analysis comparing adolescents with Attention DeficitHyperactive Disorder (ADHD) and a control group in the Conners’ Continuous Performance Test (CCPT)5 factor model, proposed by Egeland and Kovalick-Gran (2010a). Methods: The clinical group wascomposed by 28 participants with ADHD (17 male). The adolescents were divided in two groups regardingtheir ADHD subtype, inattentive or combined. Results: The ADHD group had significantly lower scoreson almost all CCPT. The 5 factors model, showed that both ADHD groups exhibited poorer results in threefactors: focused attention, sustained attention and vigilance. The ADHD subtypes did not differ in any ofthe 5 factors. Conclusions: The five factor analysis showed a good sensibility and better comprehension ofADHD symptoms; however it showed no specificity to differentiate the combined and inattentive subtypes.

O presente estudo realizou uma análise estatística comparativa entre adolescentes com e sem Transtorno de Déficit de Atenção e Hiperatividade (TDAH) no Conners 'Continuous Performance Test (CCPT). Foi utilizado o modelo de cinco fatores proposto por Egeland and Kovalick-Gran (2010a). Método: O grupo clínico foi composto por 28 participantes com TDAH (17 homens), que foram divididos em dois grupos em relação ao subtipo de TDAH (predominantemente desatento ou combinado). Resultados: O grupo TDAH teve escores significativamente mais baixos em quase todas as medidas do CCPT. Na comparação de grupos no modelo de cinco fatores, os resultados indicaram que ambos os grupos TDAH apresentaram resultados inferiores em três fatores: atenção focada, atenção sustentada e vigilância. Os subtipos de TDAH não diferiram em nenhum dos cinco fatores. Conclusões: A análise de cinco fatores mostraram uma boa sensibilidade e propiciou uma melhor compreensão dos sintomas do TDAH, no entanto ela não mostrou especificidade para diferenciar os subtipos combinado e desatento.

Effects of chronic video game use on time perception: differences between sub- and multi-second intervals.

Even though video game players frequently report losing track of time while playing, few studies have addressed whether there are long-lasting effects of such activity on time perception. We compared the performance of chronic and occasional video game players in sub- and multi-second time perception tasks. Temporal Discrimination and Temporal Bisection tasks, in the range of 100 to 1,000 milliseconds, and Time estimation and Time production tasks, in the range of 5 to 60 seconds, were used to assess sub- and multi-second time perceptions, respectively. Chronic video game players performed significantly better than occasional players on sub-second tasks, but no group difference was found for the multi-second tasks used. Sub- and multi-second time perceptions are associated to different underlying systems: automatic and cognitive controlled for sub- and multi-second tasks, respectively. We argue that video game use seems to induce more efficient implicit, rather than cognitive controlled, processing of time.

Neuropsychological rehabilitation in a patient with ruptured anterior communicating artery aneurysm: 48 month outcomes.

The neurobehavioral impairments associated with aneurysms of the anterior communicating artery (ACoA) are severe amnesia, executive problems and personality changes. Although most patients achieve a favorable neurological outcome, those cognitive deficits usually prevent return to previous activities and levels of social integration. OBJECTIVES: To report the outcomes of a neuropsychological and behavioral intervention in a 55 year-old man with very severe memory and executive dysfunctions following ACoA aneurysm rupture. METHODS: Neuropsychological intervention focused in functional adjustment in everyday life was used, including individual sessions with the patient, discussion sessions with caregivers and also work with patient at home, aiming generalization of the rehabilitation strategies. Neuropsychological and functional assessments were conducted pre and post intervention. RESULTS: Important improvements were seeing in behavior and daily living performance after treatment. CONCLUSIONS: A neuropsychological rehabilitation approach focused on goals based on the family and caregivers necessities is an efficient manner in which to carry out cognitive rehabilitation in severe cases. The importance of a supportive family should be stressed.

Os prejuízos neuro-comportamentais associados a aneurismas de artéria comunicante anterior (ACoA) são amnésia severa, dificuldades executivas e alterações de personalidade. Embora muitos pacientes alcancem uma recuperação neurológica favorável, os prejuízos cognitivos acabam impedindo o retorno às atividades prévias e ao mesmo nível de integração social. OBJETIVOS: Relatar os resultados de uma intervenção neuropsicológica e comportamental junto a um homem de 55 anos, com dificuldades severas de memória e funções executivas secundárias a ruptura de aneurisma de ACoA. MÉTODOS: Foi empregada intervenção neuropsicológica com foco na adaptação funcional na vida diária. Foram realizadas sessões individuais com o paciente, sessões de discussão com cuidadores, além de trabalho com o paciente em casa, visando a generalização das estratégias de reabilitação. Foram realizadas avaliações neuropsicológica e funcional pré e pós-intervenção. RESULTADOS: Foram observadas melhoras importantes no comportamento e no desempenho da vida diária após o tratamento. CONCLUSÕES: reabilitação neuropsicológica com foco nas necessidades dos familiares e cuidadores revelou-se eficiente maneira de realizar a reabilitação neuropsicológica em casos graves. A importância do apoio da família deve ser ressaltada.