1.
Chem Commun (Camb)
; 55(56): 8122-8125, 2019 Jul 09.
Artículo
en Inglés
| MEDLINE
| ID: mdl-31237279
RESUMEN
Pi-class glutathione S-transferase (GSTP1) is a molecular marker enzyme whose expression level is altered in various malignant tumour tissues. Herein, we report the first highly selective fluorogenic GSTP1 substrate, Ps-TG, and its membrane-permeable derivative Ps-TAc, for specific visualization of intracellular GSTP1 activity in cancer cells or epigenetically regulated GSTP1 expression.