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1.
Prague Med Rep ; 125(2): 130-137, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38761045

RESUMEN

We report a case of a 44-year-old woman surgically treated for tetralogy of Fallot who experienced an acute and extensive Stanford A type aortic dissection despite the meticulous follow-up. While aortic dilatation is prevalent in individuals with repaired tetralogy of Fallot, aortic dissection represents a rare consequence, that when it appears, is progressive and usually detected during the check-up visits. In the case reported, the dissection was unexpected and severe, and the patient's clinical state worsened suddenly, leading to death after a few days. Constant awareness for aortic aneurysms is essential in the Fallot tetralogy population, nevertheless, several causes may contribute to the acute worsening of the clinical condition until the patient's death.


Asunto(s)
Disección Aórtica , Tetralogía de Fallot , Humanos , Tetralogía de Fallot/cirugía , Tetralogía de Fallot/complicaciones , Tetralogía de Fallot/diagnóstico , Adulto , Femenino , Disección Aórtica/etiología , Disección Aórtica/cirugía , Disección Aórtica/diagnóstico , Resultado Fatal , Aneurisma de la Aorta Torácica/etiología , Aneurisma de la Aorta Torácica/cirugía , Aneurisma de la Aorta Torácica/diagnóstico
2.
Sci Rep ; 10(1): 17144, 2020 10 13.
Artículo en Inglés | MEDLINE | ID: mdl-33051585

RESUMEN

Percutaneous mitral valve repair has been increasingly performed worldwide after approval. We sought to investigate predictors of clinical outcome in patients with mitral regurgitation undergoing percutaneous valve repair. The MITRA-UMG study, a single-centre registry, retrospectively collected consecutive patients with symptomatic moderate-to-severe or severe MR undergoing MitraClip therapy. The primary endpoint was the composite of cardiovascular death or rehospitalization for heart failure. Between March 2012 and July 2018, a total of 150 consecutive patients admitted to our institution were included. Procedural success was obtained in 95.3% of patients. The composite primary endpoint of cardiovascular death or rehospitalization for HF was met in 55 patients (37.9%) with cumulative incidences of 7.6%, 26.2%, at 30 days and 1-year, respectively. In the Cox multivariate model, NYHA functional class and left ventricular end-diastolic volume index (LVEDVi), independently increased the risk of the primary endpoint at long-term follow-up. At Kaplan-Meier analysis, a LVEDVi > 92 ml/m2 was associated with an increased incidence of the primary endpoint. In this study, patients presenting with dilated ventricles (LVEDVi > 92 ml/m2) and advanced heart failure symptoms (NYHA IV) at baseline carried the worst prognosis after percutaneous mitral valve repair.


Asunto(s)
Insuficiencia de la Válvula Mitral/fisiopatología , Insuficiencia de la Válvula Mitral/cirugía , Válvula Mitral/fisiopatología , Válvula Mitral/cirugía , Anciano , Cateterismo Cardíaco/métodos , Procedimientos Quirúrgicos Cardíacos/métodos , Ecocardiografía/métodos , Femenino , Insuficiencia Cardíaca/fisiopatología , Insuficiencia Cardíaca/cirugía , Implantación de Prótesis de Válvulas Cardíacas/métodos , Hospitalización , Humanos , Estimación de Kaplan-Meier , Masculino , Estudios Retrospectivos , Resultado del Tratamiento
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