RESUMEN
Described in the literature properties of osteoplastic material "Cerabone®" have been obtained from studies in the maxilla and cancellous bone. The lack of data on the impact of «Cerabone®¼ on the dynamics of the healing of defects of compact substance of the long bones of the skeleton dictates the need for such studies. Implantation of osteoplastic material «Cerabone ®¼ was performed into the defect of rat femoral shaft followed by computer-tomographic analysis of its healing. Starting from the 30th day until the end of the experiment (120th day) there were found faint signs of rarefaction in the distal part adjacent to the defect of parent bone, with no signs of bone resorption in its proximal part. There was identified an extremely high density of the implantation site «Cerabone®¼, no visible radiographic evidence of resorption of osteoplastic material and ensuring by the latter the stability of volume of the defect in cortical bone at all stages of the experiment.
Asunto(s)
Desarrollo Óseo/efectos de los fármacos , Regeneración Ósea , Sustitutos de Huesos/administración & dosificación , Hidroxiapatitas/administración & dosificación , Animales , Ratas , Tomografía Computarizada por Rayos X , Cicatrización de Heridas/efectos de los fármacosRESUMEN
The examined groups included 58 patients with cancer, 61 subjects with pulmonary tuberculosis and 50 healthy persons as controls. The content of trace elements in blood, bronchial lavage fluid from the most affected portions of the lungs, and in pathologic and healthy lung tissues was determined by a C-115 atomic absorption spectrophotometer. The examination findings demonstrated that the content of blood serum ferric zinc and magnesium, and erythrocyte zinc, manganese, potassium and calcium was higher in patients with pulmonary tuberculosis than in those with lung cancer. At the same time the content of magnesium and calcium in bronchial lavage fluid was higher in persons with a malignant process than in those with pulmonary tuberculosis. As far as differential diagnosis of pulmonary tuberculosis and lung cancer is concerned, it is advisable to measure the levels of erythrocyte trace elements since the latter most precisely reflects their content in the lung pathologic tissue.
Asunto(s)
Líquido del Lavado Bronquioalveolar/metabolismo , Eritrocitos/metabolismo , Neoplasias Pulmonares/metabolismo , Pulmón/metabolismo , Oligoelementos/metabolismo , Tuberculosis Pulmonar/metabolismo , Líquido del Lavado Bronquioalveolar/química , Diagnóstico Diferencial , Eritrocitos/química , Humanos , Pulmón/química , Neoplasias Pulmonares/sangre , Neoplasias Pulmonares/diagnóstico , Espectrofotometría Atómica , Oligoelementos/química , Tuberculosis Pulmonar/sangre , Tuberculosis Pulmonar/diagnósticoRESUMEN
The epiphyseal cartilage and diaphysis of the tibia have been studied at dehydration and burn trauma. Dehydration produces certain disturbances in growth and formation of the bone, and burn trauma--development of dystrophic changes.