[Hypothyroidism during pregnancy risks the child's neurocognitive development. New guidelines and remaining knowledge gaps]. / Hypotyreos under graviditet riskerar barnets neurokognitiva utveckling - Nya riktlinjer och kvarstående kunskapsluckor.

Thyroid abnormalities are common during pregnancy and can affect pregnancy outcome. In 2012, the working group for endocrinology was assigned by SFOG to develop evidence based guidelines for their management. There is high quality evidence that untreated clinical hypothyroidism increases the risk of pregnancy and fetal complications. Subclinical hypothyroidism is associated with pregnancy complications. The presence of TPO-antibodies is linked to miscarriage and premature birth. It is uncertain whether subclinical hypothyroidism/maternal TPO-antibodies adversely affect the child's neurocognitive development. Reference intervals for TSH among pregnant women in Sweden need to be established.