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Zhonghua Yi Xue Za Zhi ; 96(5): 361-3, 2016 Feb 02.
Artículo en Chino | MEDLINE | ID: mdl-26875716

RESUMEN

OBJECTIVE: To explore the clinical features and microsurgical treatment strategies of giant intracranial arteriovenous malformations (AVM). METHODS: A total of 15 cases of giant intracranial AVM treated with microsurgery were analyzed retrospectively. According to the Spetzler-Martin grade, there were 4 cases of grade Ⅳ, 11 cases of grade Ⅴ. Pre-operative endovascular embolizations were carried out in 3 AVMs. RESULTS: All the included patients were confirmed as giant intracranial AVM by magnetic resonance angiography (MRA), digital subtraction angiography (DSA), 3-dimensional CT angiography (3D-CTA) before surgery. All the resected tissues were sent for pathological examination, and the diagnoses were confirmed as AVM. The average operation time of the 15 patients was 10.3 ±6.9 hours. After 1-3 months, all the patients were rechecked by DSA, the large vascular malformations in 12 cases were completely resected, 3 cases had a small amount of residual further treated with gamma knife treatment. Magnetic resonance imaging (MRI) and MRA examination indicated that the residual AVM was occluded after 12 months. Patients were followed up at 6, 12 and 24 months after operation, and assessed by Glasgow outcome scale (GOS) score: 13 cases good, 1 cases mild disability, 1 cases severe disability; the good rate was 86.6%, with no dead case. CONCLUSION: Sufficiently preoperative preparation, appropriate operative methods and skills are necessary to treat giant intracranial arteriovenous malformation.


Asunto(s)
Malformaciones Arteriovenosas Intracraneales , Microcirugia , Angiografía de Substracción Digital , Terapia Combinada , Personas con Discapacidad , Doxorrubicina , Embolización Terapéutica , Escala de Consecuencias de Glasgow , Humanos , Angiografía por Resonancia Magnética , Imagen por Resonancia Magnética , Metotrexato , Radiocirugia , Estudios Retrospectivos , Resultado del Tratamiento
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