Simultaneous occurrence of selective ACTH insensitivity, achalasia and alacrimia accompanied by hyperlipoproteinaemia.

An extremely rare clinical syndrome on a 7-year-old-girl is presented. Besides isolated glucocorticoid insufficiency, achalasia and alacrima disturbance of the lipid metabolism was also detected--being a special feature of this case. The details of the endocrine workup is discussed, providing clues for the possible pathomechanism. The correct diagnosis and specific therapy is of utmost importance in the everyday life of the patient.

[Simultaneous occurrence of selective ACTH deficiency , achalasia, alacrimia and hyperlipoproteinemia]. / Szelektív ACTH érzéketlenség, achalasia és alacrimia együttes elöfordulása hyperlipoproteinaemiával.

An extremely rare clinical syndrome on a 7-year-old girl is presented. Besides isolated glucocorticoid insufficiency, achalasia and alacrimia disturbance of the lipid metabolism was also detected--this is a special feature of this case. The details of the endocrine workup is discussed, providing clues for the possible pathomechanism. The correct diagnosis and specific therapy is of utmost importance in the everyday life of the patient.

Active immunization of children exposed to varicella infection in a hospital ward using live attenuated varicella vaccine given subcutaneously or intracutaneously.

Active immunization using Takahashi OKA live attenuated varicella vaccine was carried out fire 5 times to prevent the spread of "imported" varicella in a hospital ward. Susceptibility was previously tested by serological examinations: 14 children were vaccinated subcutaneously, the other 19 received the vaccine intracutaneously. Vaccination within a few days following exposure provided complete immunity in the great majority of cases. Intracutaneous administration was nearly as protective as the subcutaneous one.