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1.
Int J Gynaecol Obstet ; 161(1): 234-240, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-36200671

RESUMEN

OBJECTIVE: To evaluate the prevalence of intraperitoneal adhesions after repeated cesarean delivery and its associated personal and surgical risk factors. METHODS: This prospective cohort study was conducted at the delivery ward at Fayoum University Hospital from October 2020 to December 2021. Women were recruited according to predetermined inclusion and exclusion criteria. Eligible women were interviewed, and data were obtained for personal history, past surgical and obstetrical history, and data about the current delivery. Nair's scoring system was used to evaluate intraperitoneal adhesions. Postoperative data and complications were reported. RESULTS: Three hundred women were recruited. Moderate to severe adhesions occurred in 186 patients (62%). These patients had a significantly prolonged hospital stay and were delivered by expert surgeons (P < 0.001 and P = 0.008, respectively). The adhesion score correlated positively with patients' age (P < 0.001), parity (P < 0.001), interpregnancy interval (P = 0.033), duration of hospital admission either previously or in the current delivery (P = 0.001 and P < 0.001), time to ambulation (P < 0.001), time to intestinal movement (P < 0.001), operative time (P < 0.001), and surgeons' age and experience (both P = 0.015). CONCLUSION: Adhesions led to increased maternal morbidity. Multiple contributing factors were significantly related to adhesions with multiple cesarean deliveries.


Asunto(s)
Cesárea , Humanos , Femenino , Embarazo , Cesárea/efectos adversos , Prevalencia , Estudios Prospectivos , Adherencias Tisulares/epidemiología , Adherencias Tisulares/etiología , Paridad , Factores de Riesgo
3.
J Obstet Gynaecol ; 42(6): 1734-1738, 2022 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-36168195

RESUMEN

This was a cross sectional study surveying a total of 451 physicians. A questionnaire was constructed and distributed electronically to the participants. The main outcome measure was evaluation of physicians' knowledge, attitude, and practice towards VBAC in Egypt. Although 76.3% of the physicians agreed to present VBAC as an option, 38.1% disagreed with encouraging it. Also, a large proportion of them advised against the induction of labour and refused it if post-term (69.4% and 76.1%, respectively). The physicians' attitude towards VBAC was to allow vaginal birth if the patient went into spontaneous labour (72.3%) and perform repeat CS if not in labour (86.7%). Fear of complications (78.71%) was the most common cause of not conducting VBAC. The consensus of practice was to present VBAC as an option for women with a single Caesarean scar; however, one-third of them did not encourage VBAC. They strongly refused the induction of labour. Impact StatementWhat is already known on this subject? This is the first study to evaluate physicians' knowledge, attitude, and practice towards VBAC in Egypt and the Arab world.What do the results of this study add? From the current survey of the practice of the obstetricians in Egypt, the consensus of practice was to present VBAC as an option for women with a single Caesarean scar; however, one-third of them did not encourage VBAC. They strongly refused the induction of labour. The presence of labour pain is the strongest determinant to allow VBAC, while the vast majority of obstetricians were willing to conduct ERCS in the absence of labour pain. This contributed significantly to the rising rates of CS in Egypt.What are the implications of these findings for clinical practice and/or further research? Physicians' attitude towards VBAC should be evaluated in countries with higher rates of CS deliveries. Women's perspectives and attitude towards VBAC should be evaluated.


Asunto(s)
Dolor de Parto , Médicos , Parto Vaginal Después de Cesárea , Cesárea Repetida , Cicatriz , Estudios Transversales , Egipto , Femenino , Conocimientos, Actitudes y Práctica en Salud , Humanos , Embarazo
4.
J Obstet Gynaecol Res ; 48(12): 3286-3291, 2022 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-36065788

RESUMEN

OBJECTIVE: To evaluate the impact of repair of uterovaginal prolapse using sacrospinous hysteropexy on female sexual function. METHODS: A cross-sectional study was conducted at the Urogynecology Clinic of the Suez Canal University Hospital from May 2014 to April 2019. Twenty-seven women with a diagnosis of uterovaginal prolapse and wishing to preserve their uteri were recruited. Sacrospinous ligament fixation was done. Sexual symptoms were assessed using the female sexual function index (FSFI) questionnaire just before and 6 months after the operation. RESULTS: The mean age of the participants was 36.5 ± 4 years. Sacrospinous hysteropexy only was performed for three women. Additional procedures included anterior colporrhaphy (12), posterior colporrhaphy (9), and perineorrhaphy (15). There was a significant improvement in pre- and postoperative patients' orgasm (3.1 ± [0.8] vs. 3.7 ± [1.1]; p value = 0.03) and satisfaction (3.4 ± [0.6] vs. 4.2 ± [0.8]; p value < 0.001) while there was worsening of pain (4.3 ± [1.5] vs. 3.2 ± [1.6]; p value = 0.017). There was insignificant improvement in the other three domains as well as total score of FSFI, with all patients having sexual dysfunction. CONCLUSION: Sacrospinous hysteropexy was associated with significant improvement orgasm and satisfaction domains of FSFI and significant worsening of pain.


Asunto(s)
Procedimientos Quirúrgicos Ginecológicos , Prolapso Uterino , Femenino , Humanos , Adulto , Procedimientos Quirúrgicos Ginecológicos/efectos adversos , Procedimientos Quirúrgicos Ginecológicos/métodos , Estudios Transversales , Resultado del Tratamiento , Prolapso Uterino/cirugía , Dolor
5.
J Obstet Gynaecol ; 42(5): 1117-1121, 2022 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-34994292

RESUMEN

This was a cross sectional study with a prospective design conducted from October 2018 to October 2019. We recruited patients at risk for FGR and normal pregnant women. Each patient had ultrasound examination for the umbilical cord diameter in the 28th, 32nd, 36th, and the 40th week, Foetal growth restriction developed in 10/76 (13.2%) patients in the at risk group. The umbilical cord diameter was significantly lower in the at risk group (1.8 ± 0.2 versus 2.0 ± 0.2 in the control group with a p value of <.001). The umbilical cord diameter was highly predictive for the occurrence of FGR at each antenatal care visit as well as at delivery. We concluded that the umbilical cord diameter was a significant predictor of foetal growth restriction when applied through the antenatal care visits. It is a simple and easy method causing no distress for the patients.IMPACT STATEMENTWhat is already known on this subject? Conflicting results exist regarding the predictive role of the umbilical cord in foetal growth restriction.What do the results of this study add? Foetal umbilical cord diameter was correlated significantly to foetal weight and had a significant predictive role in the prediction of FGR. The cut off values for the umbilical cord diameter in women with FGR were not evaluated before.What are the implications of these findings for clinical practice and/or further research? Comparing the ultrasound findings with histopathologic examination of the umbilical cord and the placentas would be recommended.


Asunto(s)
Retardo del Crecimiento Fetal , Peso Fetal , Estudios Transversales , Femenino , Retardo del Crecimiento Fetal/diagnóstico por imagen , Retardo del Crecimiento Fetal/patología , Humanos , Placenta/patología , Embarazo , Ultrasonografía Prenatal , Cordón Umbilical/diagnóstico por imagen
6.
Int J Gynaecol Obstet ; 156(2): 304-308, 2022 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-33507541

RESUMEN

OBJECTIVE: To evaluate the predictive role of the uterocervical angle and the cervical length in preterm birth. METHODS: This was cross-sectional analytical study, recruiting 167 women at high-risk for preterm birth (delivery before 37 weeks of pregnancy). They had transvaginal ultrasound for evaluation of the uterocervical angle and the cervical length between at 30 and 32, 32+1 and 34, and 34+1 and 36+1  weeks of pregnancy. The primary outcome was to determine the predictive role of the uterocervical angle and the cervical length in preterm birth. RESULTS: The mean uterocervical angle was significantly greater in those who delivered preterm (115.4° ± 9.1° versus 101.1° ± 8.3°, p < 0.001). The cervical length was insignificantly shorter in the same group (27.9 ± 4.0 and 29.1 ± 4.1 mm, respectively, p = 0.067). A uterocervical angle of 105° or more predicted preterm birth with sensitivity and specificity of 86.1% and 60.4%, respectively. A cervical length of 25 mm or less had sensitivity and specificity of 27.8% and 85.8%, respectively. CONCLUSION: A uterocervical angle greater than 105° poses a high risk for preterm deliveries. It provides a higher diagnostic performance in high-risk patients than cervical canal length measurement.


Asunto(s)
Nacimiento Prematuro , Medición de Longitud Cervical , Cuello del Útero/diagnóstico por imagen , Estudios Transversales , Femenino , Humanos , Recién Nacido , Embarazo , Nacimiento Prematuro/epidemiología , Útero/diagnóstico por imagen
7.
Eur J Contracept Reprod Health Care ; 27(1): 23-27, 2022 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-34704516

RESUMEN

OBJECTIVES: The aims of the study were to evaluate the effects of two types of intrauterine contraceptive device (IUCD) on uterine artery Doppler indices. METHODS: A multicentre randomised clinical trial was conducted between November 2019 and August 2020. Sixty-six multiparous women aged 18-45 years seeking intrauterine contraception were randomly assigned to receive either the levonorgestrel-releasing intrauterine system (LNG-IUS) or the copper intrauterine device (Cu-IUD). Each group comprised 33 participants. Primary outcome measures were menstrual changes and changes in uterine artery Doppler indices 3 and 6 months after IUCD insertion. Secondary outcomes measures were the relation between Doppler indices and menstrual changes, adverse effects of the assigned contraceptive method and user acceptability of the method. RESULTS: Uterine artery pulsatility index (PI) and resistance index (RI) were significantly higher among women in the LNG-IUS group (p < .001 at 6 months). Whereas the number of women reporting heavy menstrual bleeding decreased at 3 and 6 months in the LNG-IUS group it significantly increased in the Cu-IUD group (p < .001 at 6 months). Multiple logistic regression analysis of participant characteristics and occurrence of heavy menstrual bleeding revealed a significant association with uterine artery RI (p < .01) and the type of IUCD (p < .001). CONCLUSION: IUCDs are associated with Doppler changes that may be associated with their reported side effects.


Asunto(s)
Dispositivos Intrauterinos de Cobre , Dispositivos Intrauterinos Medicados , Arteria Uterina , Adolescente , Adulto , Anticonceptivos Femeninos/efectos adversos , Femenino , Humanos , Dispositivos Intrauterinos de Cobre/efectos adversos , Dispositivos Intrauterinos Medicados/efectos adversos , Levonorgestrel/efectos adversos , Persona de Mediana Edad , Ultrasonografía Doppler , Arteria Uterina/diagnóstico por imagen , Adulto Joven
8.
J Perinat Med ; 49(6): 674-677, 2021 Jul 27.
Artículo en Inglés | MEDLINE | ID: mdl-34062628

RESUMEN

OBJECTIVES: This study aimed to evaluate anxiety and depression in pregnant women during this global disease. METHODS: This was a cross-sectional study recruiting 120 pregnant women. The study was conducted at the outpatient clinic of a tertiary hospital. We recruited women attending for antenatal care. Anxiety was evaluated using an Arabic validated Kuwait University Anxiety Scale (KUAS). Depression was evaluated using a validated Arabic form of the Edinburgh Postnatal Depression Scale (EPDS). RESULTS: The study included 48 (40%) nulliparous and 72 (60%) multiparous women. The mean KUAS scores for nulliparous and multiparous women were 45.27±10.78 and 47.28±10.62. Both nulliparous and multiparous women had a fairly high possibility of depression. Fifty-three (44.2%) of them reported scores ≥ of 14. Ninety-three (77.5%) women thought that COVID-19 pandemic would affect their pregnancies. There was a significant association between the number of women reporting fear related to the COVID-19 pandemic and their KUAS and EPDS scores (p-value <0.001 each). CONCLUSIONS: COVID-19 affected the mental health of pregnant women to a great extent. Care should be directed to measures that would decrease the impact of this pandemic on vulnerable populations.


Asunto(s)
Ansiedad/epidemiología , COVID-19 , Depresión/epidemiología , Complicaciones del Embarazo/psicología , Adulto , Estudios Transversales , Egipto/epidemiología , Femenino , Humanos , Embarazo , Complicaciones del Embarazo/epidemiología , Adulto Joven
9.
BMC Pregnancy Childbirth ; 21(1): 286, 2021 Apr 09.
Artículo en Inglés | MEDLINE | ID: mdl-33836692

RESUMEN

BACKGROUND: The current fact of increasing rates of cesarean deliveries is a catastrophe. Recurrent cesareans result in intraperitoneal adhesions that would lead to maternal morbidity during delivery. Great efforts are directed towards the prediction of intraperitoneal adhesions to provide the best care for laboring women. The aim of the current study was to evaluate the role of abdominal striae and cesarean scar characters in the prediction of intraperitoneal adhesions. METHODS: This was a case- control study conducted in the emergency ward of the obstetrics and gynecology department of a tertiary hospital from June to December 2019. The study was carried on patients admitted to the ward fulfilling particular inclusion and exclusion criteria. The study included two groups, group one was assessed for the presence of striae, and the degree of intraperitoneal adhesions was evaluated during the current cesarean section. Group two included patients without evidence of abdominal striae. They were evaluated for the severity of adhesions also after evaluation of the previous scar. Evaluation of the striae was done using Davey's scoring system. The scar was assessed using the Vancouver Scar Scale. The modified Nair's scoring system was used to evaluate intraperitoneal adhesions. RESULTS: The study group included 203 women, while the control group included 205 women. There were significant differences in the demographic characters of the recruited patients (p-value 0.001 for almost all variables). The mean Davey score in those with mild, moderate, and severe striae was 1.82 ± 0.39, 3.57 ± 0.5, and 6.73 ± 0.94, respectively (p-value < 0.001). Higher scores for the parameters of the Vancouver scale were present in patients with severe striae (1.69 ± 1.01, 1.73 ± 0.57, 2.67 ± 1.23, and 1.35 ± 1.06 for scar vascularity, pigmentation, pliability, and height respectively with a p-value of < 0.001 each). Thick intraperitoneal adhesions were noted significantly in women with severe striae [21 (43.75%), p-value < 0.001)]. The Davey's and Vancouver scores showed highly significant predictive performance in the prediction of intraperitoneal adhesions (p-value < 0.001). CONCLUSION: Abdominal striae and cesarean scar were significant predictors for intraperitoneal adhesions.


Asunto(s)
Cesárea Repetida/efectos adversos , Cicatriz/diagnóstico , Complicaciones Posoperatorias/epidemiología , Estrías de Distensión/diagnóstico , Adherencias Tisulares/epidemiología , Adulto , Estudios de Casos y Controles , Cesárea Repetida/estadística & datos numéricos , Cicatriz/etiología , Femenino , Humanos , Cavidad Peritoneal/patología , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/patología , Embarazo , Medición de Riesgo , Índice de Severidad de la Enfermedad , Estrías de Distensión/etiología , Adherencias Tisulares/etiología , Adherencias Tisulares/patología , Adulto Joven
10.
J Obstet Gynaecol Res ; 47(4): 1572-1578, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33530133

RESUMEN

OBJECTIVE: To evaluate domestic violence and sexual dysfunction in infertile women. MATERIALS AND METHODS: We recruited women complaining of infertility (primary or secondary infertility). A control group of fertile women attending the outpatient clinic for any concern was recruited. Domestic violence was evaluated using the Arabic validated NorVold Domestic Abuse Questionnaire (NORAQ). Female sexual function was evaluated using the Arabic validated female sexual function index. RESULTS: There was no significant difference between both groups in rates of exposure to violence (p-value 0.830). Primary infertility was a significant contributing factor in infertile women's exposure to violence (p-value 0.001). All the studied population had female sexual dysfunction, with more dysfunction was reported by the infertile women (total score 18.87 ± 5.92, 19.51 ± 5.42, p-value 0.072). They differed significantly in arousal (2.83 ± 1.33, 3.13 ± 1.29, p-value 0.001) and satisfaction (3.98 ± 1.27, 4.28 ± 1.28, p-value 0.003) which were impaired in infertile women. CONCLUSIONS: The recruited infertile women were exposed to violence. Emotional abuse was the most common reported type of violence. Sexual dysfunction was reported in the entire studied population with no significant difference relating to fertility.


Asunto(s)
Violencia Doméstica , Infertilidad Femenina , Estudios Transversales , Egipto/epidemiología , Femenino , Humanos , Infertilidad Femenina/epidemiología , Prevalencia , Factores de Riesgo
11.
J Obstet Gynaecol Res ; 47(4): 1330-1336, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33438313

RESUMEN

AIM: The aim of the study was to compare the rates of postpartum endometritis due to uterine cleaning and no cleaning in patients delivered by elective cesarean section. METHODS: This was a randomized clinical trial conducted at the Obstetrics and Gynecology Department, Suez Canal University Hospital, Ismailia, from June 2019 to November 2019. We recruited patients undergoing cesarean delivery aged 18-45 years with singleton pregnancy, intact membranes, either first or repeated delivery, without labor pains. Patients were allocated into two groups, uterine cleaning (336 patients) and no cleaning (312 patients). The main outcome measure was the occurrence of postpartum endometritis. RESULTS: Both groups were matched in their demographic characters. Twelve patients (3.6%) developed endometritis in the cleaning group versus one patient (0.3%) in the other one. Estimated blood loss was 754.35 ± 247.13 and 730.36 ± 232.77 for the cleaning and no cleaning groups, respectively, with a P value of 0.201. Septic wound infection (21 patients, 6.3%) was predominant in the cleaning group. CONCLUSION: Uterine cleaning after delivery of the placenta during CS can be omitted as a surgical step during the operation. It was associated with increased rates of postpartum endometritis and blood loss.


Asunto(s)
Cesárea , Endometritis , Infección Puerperal , Adolescente , Adulto , Cesárea/efectos adversos , Endometritis/epidemiología , Endometritis/prevención & control , Femenino , Humanos , Persona de Mediana Edad , Periodo Posparto , Embarazo , Infección Puerperal/epidemiología , Infección Puerperal/prevención & control , Útero , Adulto Joven
12.
J Gynecol Obstet Hum Reprod ; 50(5): 101937, 2021 May.
Artículo en Inglés | MEDLINE | ID: mdl-33045448

RESUMEN

OBJECTIVE: Evaluation of the effectiveness of ultrasound-guided trans-vaginal ovarian needle punctures on improving the management of women with polycystic ovary syndrome resistant to clomiphene citrate. METHODS: This was a randomized clinical trial conducted in a tertiary Hospital, from June 2016 to December 2018. We recruited twenty- seven women with resistant PCOS with either primary or secondary infertility. They were randomly assigned into two groups. Group one included patients who had a trial of induction using aromatase inhibitors (Letrozol 2.5 mg twice daily from day 2 of the cycle and for 5 days) and FSH administered with 75 IU daily from cycle day 3 and maintained for up to the 14th day of the cycle. Group two included patients who had transvaginal ovarian puncture prior to induction with AIs and gonadotropins. Folliculometery was done starting from day 9 of the cycle. When the follicle reaches a size of 18-25 mm, HCG was given to enhance ovulation. RESULTS: There was a significant improvement in the hormonal profile (serum LH, FSH, and testosterone with a p- value of 0.0001, 0.007, and 0.0001 respectively) in the study group after one month of treatment. The overall number of ovulatory cycles was significantly higher in the study group than the control group [84 % (62/74), 62.8 % (49/78), p- value 0.006 respectively]. The cumulative pregnancy rates were significantly higher in the study group [33.3 % (9/27)]. No complications related to the procedure were reported. CONCLUSION: transvaginal ovarian needle puncture is a safe and effective procedure.


Asunto(s)
Infertilidad Femenina/terapia , Ovario/cirugía , Inducción de la Ovulación/métodos , Síndrome del Ovario Poliquístico/terapia , Punciones/métodos , Adulto , Inhibidores de la Aromatasa/administración & dosificación , Clomifeno/uso terapéutico , Esquema de Medicación , Resistencia a Medicamentos , Antagonistas de Estrógenos/uso terapéutico , Femenino , Hormona Folículo Estimulante/administración & dosificación , Humanos , Infertilidad Femenina/sangre , Infertilidad Femenina/tratamiento farmacológico , Letrozol/administración & dosificación , Hormona Luteinizante/sangre , Folículo Ovárico , Síndrome del Ovario Poliquístico/sangre , Síndrome del Ovario Poliquístico/tratamiento farmacológico , Embarazo , Índice de Embarazo , Testosterona/sangre , Ultrasonografía Intervencional , Vagina , Adulto Joven
13.
Eur J Contracept Reprod Health Care ; 25(4): 245-250, 2020 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-32484369

RESUMEN

OBJECTIVE: To assess the knowledge, attitude, and practice of private obstetricians and gynaecologists towards abortion, post-abortion care, and post-abortion family planning. PATIENTS AND METHODS: A cross-sectional study, from June 2017 to May 2018, using a self-administered questionnaire of 150 obstetricians/gynaecologists at private clinics, centres, hospitals in Ismailia, Egypt. The questionnaire was composed of four broad sections: section one was about the socio-demographic characteristics of the participants; section two was about physicians' knowledge, attitude and practices regarding abortion; section three was about their attitudes and practices regarding post-abortion family planning and screening for sexually transmitted diseases (STDs) in patients presenting for induced abortion; and section four was about the socio-demographic characteristics of women seeking induced abortion taken from the physicians' views. RESULTS: Only 15.2% of participants had performed an abortion for unwanted pregnancies at ≤12 weeks vs. 3.8% for unwanted pregnancies >12 weeks' gestation. The most common reason for not performing an abortion was religious prohibition (80.35% vs. 86.6% for unwanted pregnancy ≤12 and > 12 weeks, respectively). Social causes were the most common reason for seeking an induced abortion. None of the physicians used manual vacuum aspiration (MVA) for abortion or had received training in MVA. Post-abortion family planning counselling was offered by 20.5% of physicians, while 13.6% screened for STDs. CONCLUSIONS: The majority of private obstetricians/gynaecologists in Ismailia, Egypt, do not perform abortions for unwanted pregnancies because of their religious beliefs. Post-abortion screening for STDs and family planning services are not sufficiently integrated into post-abortion care.


Asunto(s)
Aborto Inducido/psicología , Cuidados Posteriores/psicología , Ginecología/organización & administración , Obstetricia/organización & administración , Médicos/psicología , Práctica Privada , Adulto , Actitud del Personal de Salud , Estudios Transversales , Egipto , Femenino , Conocimientos, Actitudes y Práctica en Salud , Humanos , Masculino , Persona de Mediana Edad , Embarazo
14.
Hypertens Pregnancy ; 39(3): 302-307, 2020 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-32406308

RESUMEN

OBJECTIVES: Evaluation of the association between fetal gender, serum beta-human chorionic gonadotropin, and serum testosterone, and preeclampsia. METHODS: Case-control study conducted at the Obstetrics and Gynecology Department. 120 patients divided into study group (patients with preeclampsia subdivided into mild and severe) and control group (normotensive women). INTERVENTIONS: Fetal gender was determined. Serum testosterone and HCG levels were estimated at 32 weeks or at the time of diagnosis of preeclampsia (study group) or recruitment (control group). RESULTS: Positive association between the male gender of the fetus and preeclampsia. Increased HCG and Testosterone were associated with developing preeclampsia. CONCLUSION: The mechanism of preeclampsia could be androgen-mediated. There is a significant correlation between serum HCG and testosterone and preeclampsia.


Asunto(s)
Presión Sanguínea/fisiología , Gonadotropina Coriónica/sangre , Preeclampsia/sangre , Testosterona/sangre , Adulto , Biomarcadores/sangre , Estudios de Casos y Controles , Femenino , Humanos , Masculino , Embarazo , Factores Sexuales
15.
Hypertens Pregnancy ; 39(3): 319-325, 2020 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-32421401

RESUMEN

OBJECTIVE: Assess the efficacy and safety of carbetocin, versus oxytocin in the prevention of postpartum hemorrhage in hypertensive women. STUDY DESIGN: A randomized clinical trial. SETTING: Obstetrics and Gynecology Department of Suez Canal University Hospital. PATIENTS: One hundred and sixty hypertensive pregnant women who underwent CS. INTERVENTIONS: Patients were randomized to receive either 10 IU oxytocin or 100 µg carbetocin. Primary outcomes included estimated blood loss, blood transfusion, hemoglobin (HB), and hematocrit changes pre- and post-delivery and the use of additional uterotonics. RESULTS: The postoperative HB was not different from preoperative HB in the carbetocin group (11.8 ± 1.2 vs. 11.2 ± 1.2 g/dL) while it decreased significantly in the oxytocin group (12.1 ± 3.8 vs. 10.4 ± 1.1 g/dL, p < 0.001). Blood loss was significantly more among the oxytocin group (679.5 ± 200.25 vs. 424.75 ± 182.59 ml) in the carbetocin group (p < 0.001). Nausea, vomiting, and sweating were reported more significantly in oxytocin group patients. CONCLUSION: Carbetocin was more effective than oxytocin in reducing intraoperative and postoperative blood loss.


Asunto(s)
Cesárea/efectos adversos , Hipertensión Inducida en el Embarazo/fisiopatología , Oxitócicos/uso terapéutico , Oxitocina/análogos & derivados , Oxitocina/uso terapéutico , Hemorragia Posparto/prevención & control , Adulto , Método Doble Ciego , Femenino , Humanos , Embarazo , Resultado del Tratamiento
16.
Int J Gynaecol Obstet ; 150(1): 72-76, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-32286686

RESUMEN

OBJECTIVES: To investigate the role of sildenafil citrate in improving ovulation induction success rate in women with unexplained infertility. METHODS: A randomized clinical trial from January to December 2018 of 80 women with unexplained infertility randomized into two groups. Both groups received 100 mg clomiphene citrate once daily from days 3-7 of the menstrual cycle. The study group also received 25 mg oral sildenafil citrate twice daily from days 8-12 of the same cycle. Transvaginal ultrasound assessed ovulation, endometrial thickness, and number of follicles. Pregnancy was assessed 2 weeks after ovulation. Primary outcome measures were endometrial thickness, number of mature follicles, and pregnancy rates. RESULTS: Pregnancy rates (26 (65%) and 16 (40%), P=0.043) and endometrial thickness (10.4 ± 1.4 and 9.2 ± 1.9, P=0.007) were significantly higher in the study group. More women in the study group reported adverse effects compared with the control group (17 [42.5%] vs 9 [22.5%]; P=0.034), with headache the most common adverse effect in the study group, reported by 8 (20.0%) patients. CONCLUSION: Adding sildenafil citrate improved ovulation success rate and increased pregnancy rate. PAN AFRICAN CLINICAL TRIAL REGISTRY: PACTR201907658492123.


Asunto(s)
Fármacos para la Fertilidad Femenina/administración & dosificación , Infertilidad Femenina/tratamiento farmacológico , Inducción de la Ovulación/métodos , Citrato de Sildenafil/administración & dosificación , Adulto , Quimioterapia Combinada , Femenino , Fármacos para la Fertilidad Femenina/efectos adversos , Humanos , Folículo Ovárico/efectos de los fármacos , Embarazo , Índice de Embarazo , Citrato de Sildenafil/efectos adversos , Citrato de Sildenafil/uso terapéutico , Adulto Joven
17.
BMC Pregnancy Childbirth ; 20(1): 191, 2020 Mar 30.
Artículo en Inglés | MEDLINE | ID: mdl-32228499

RESUMEN

BACKGROUND: Antenatal cervical length measurement has paramount importance in the prediction of labor. It was compared to the Bishop Score and incorporated in the modified Bishop score due to its relevance and convenience. It is a more accurate tool that imposes no harm or distress to the patients. The study aimed to evaluate the role of antenatal cervical length measurement in the prediction of a successful vaginal birth and its relation to the duration of labor. METHODS: This was a prospective cohort study, conducted at the emergency ward of obstetrics and gynecology department. We recruited 162 women over 1 year from January 2018 to January 2019. Women eligible for the study had a transvaginal ultrasound for the examination of the cervical length before the onset of labor. The success of vaginal delivery was evaluated. RESULTS: The mean cervical length (mm) was 43.3 ± 8.0. The majority of the patients labored spontaneously [102 (63.0%)] while the remaining ones required induction of labor due to different causes. One hundred and eight patients (66.7%) had a successful vaginal delivery. The cervical length was significantly shorter among patients who delivered vaginally than those delivered by CS (P-value < 0.001). Multiple factors had a significant role in the prediction of the mode of delivery (cervical length, BMI, the onset of labor, parity). Maternal body mass index and labor induction were associated with a prolonged duration of the active phase of labor. CONCLUSION: Antenatal cervical length measurement predicted the mode of delivery as well as the gestational age at which delivery ensued. It can be used in patients' counseling regarding the mode of delivery.


Asunto(s)
Medición de Longitud Cervical , Cuello del Útero/diagnóstico por imagen , Parto Obstétrico/métodos , Adulto , Egipto/epidemiología , Femenino , Edad Gestacional , Humanos , Valor Predictivo de las Pruebas , Embarazo , Estudios Prospectivos , Ultrasonografía Prenatal
18.
Eur J Obstet Gynecol Reprod Biol ; 242: 126-130, 2019 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-31585239

RESUMEN

STUDY OBJECTIVE: To evaluate the late suture- related complications of sacrospinous ligament fixation (SSLF) as a treatment for uterovaginal prolapse and their impact on the quality of life. DESIGN: A prospective cohort study. SETTINGS: The Obstetrics and Gynecology Department of Suez Canal University Hospitals, Ismailia, Egypt from January 2014 to June 2018. PATIENTS: We recruited sixty women with uterovaginal prolapse. INTERVENTIONS: Patients underwent SSLF using the Capio suture recapturing device with non-absorbable suture material (0 braided Polyester). Postoperative visits were at six weeks then at 6, 12, 18, and 24 months after the procedure. MEASUREMENTS AND MAIN RESULTS: Outcome measures were the rate and timing of suture- related and the quality of life using the pelvic floor impact questionnaire-7 at 24 months postoperatively. The mean age of the studied population was 45.7 ± 9.8 years. Suture- related complications occurred in 55% (33/60) of patients, with vaginal discharge the most commonly reported symptom. Most of them presented in the 1st year after the procedure 72.7% (24/33), and 25% (15/60) had suture removal. However, there was a significant improvement in patients' quality of life. CONCLUSION: Sacrospinous ligament fixation has a positive impact on the quality of life, yet associated with significant but prominent suture- related complications.


Asunto(s)
Procedimientos Quirúrgicos Ginecológicos/efectos adversos , Prolapso de Órgano Pélvico/cirugía , Complicaciones Posoperatorias/etiología , Adulto , Anciano , Femenino , Humanos , Persona de Mediana Edad , Estudios Prospectivos , Calidad de Vida
19.
Eur J Obstet Gynecol Reprod Biol ; 224: 170-174, 2018 May.
Artículo en Inglés | MEDLINE | ID: mdl-29609185

RESUMEN

OBJECTIVE: To evaluate the impact of repair of uterovaginal prolapse using sacrospinous hysteropexy and vaginal wall repair on the bladder function. STUDY DESIGN: The study was conducted at the urogynecology clinic of Suez Canal University Hospitals, Ismailia from January 2014 to March 2016. This study included women with a diagnosis of uterovaginal prolapse and wishing to preserve their uteri. Bladder function was evaluated through assessment of urological symptoms using a standardized questionnaire - the urogenital distress inventory (UDI-6) - in addition to urodynamic studies just before and six-months after the sacrospinous hysteropexy ±â€¯associated vaginal wall repair operation. RESULTS: Twenty-seven patients completed the study with a mean age of 36.5 ±â€¯4 years. Only 3 women had sacrospinous hysteropexy with no additional procedures. Other procedures included anterior colporrhaphy (12), posterior colporrhaphy (9) and perineorrhaphy (15). Based on UDI-6, there was no significant difference between the pre- and post-operative symptoms of stress urinary incontinence (SUI) [8/27 (29.6%) vs. 9/27 (33.3%) respectively; p value = 0.7]. The pre- and post-operative symptoms of urge urinary incontinence were also insignificantly different [13/27 (48.1%) vs. 15/27 (55.5%); p value = 0.5]. The total score of UDI-6 increased from 24.5 ±â€¯(14.2) to 32.8 ±â€¯(29.4) which was not statistically significant (p value = 0.12). Urodynamically, voiding dysfunction was found less frequently after the operation, however the difference was statistically insignificant [9/27 (33.3%) vs. 8/27 (29.6%); p value = 0.7]. CONCLUSION: Sacrospinous hysteropexy and associated vaginal wall repair do not affect the bladder function either subjectively or objectively.


Asunto(s)
Procedimientos Quirúrgicos Ginecológicos , Vejiga Urinaria/fisiología , Prolapso Uterino/cirugía , Vagina/cirugía , Adulto , Femenino , Humanos , Persona de Mediana Edad , Estudios Prospectivos
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