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Sci Rep ; 14(1): 22500, 2024 09 28.
Artículo en Inglés | MEDLINE | ID: mdl-39341948

RESUMEN

The present research extensively investigates the significance of the sac centerline length of the anterior cerebral artery (ACA) on aneurysm rupture risk. Hemodynamic factors influencing aneurysm rupture are assessed to identify critical regions prone to rupture. Wall shear stress is analyzed by modeling blood flow in three real saccular ACA cases with varying sac centerline lengths. A one-way fluid-solid interaction (FSI) model is employed to examine the interaction between blood flow and vessel deformation. The computational study reveals that wall shear stress on the ACA saccular aneurysm wall is significantly higher when the sac centerline length is shorter. Conversely, the mean oscillatory index changes with different sac centerline lengths, showing that an increase in sac centerline length leads to higher blood oscillation within the sac area in ACA cases.


Asunto(s)
Aneurisma Roto , Arteria Cerebral Anterior , Hemodinámica , Aneurisma Intracraneal , Humanos , Aneurisma Roto/fisiopatología , Aneurisma Intracraneal/fisiopatología , Medición de Riesgo , Circulación Cerebrovascular/fisiología , Modelos Cardiovasculares , Estrés Mecánico , Simulación por Computador , Velocidad del Flujo Sanguíneo
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