Dataset for tracing phosphorus sources by the oxygen isotopes of phosphate.

Phosphorus is an essential nutrient for the growth of marine life. Especially in the East China Sea (ECS) where phosphorus is limited compared to the rest of China's sea, the external input of phosphorus can cause changes in primary productivity, and even induce in harmful algal blooms. In May 2020, the National Natural Science Foundation of China carried out a scientific investigation in the shared Spring Voyage in the ECS. We choose the area between 120.93 ˚ E-125.9 ˚ E and 26.08˚ N - 32.35 ˚ N as research sites for the analysis of the main sources of phosphate in the ECS during summer. The samples were all from the voyage of the research ship (Xiangyanghong 18). Dissolved inorganic phosphorus in seawater was enriched, and dissolved inorganic phosphorus was extracted. Then we measured the oxygen isotopes of phosphate in seawater and introduced the two-component mixing model for the analysis of potential sources of phosphate. In order to further quantitatively analyze the contribution rate of phosphate from different sources in the ECS, we choose a Bayesian isotope mixing model. These data can be used to analyze the contribution of phosphate from different sources in seawater and are helpful to explore the influencing factors of phosphate in the ECS.

Dataset for atmospheric transport of nutrients during a harmful algal bloom.

The data presented in this article are related to the research article entitled "Atmospheric transport of nutrient matter during a harmful algal bloom"[1]. These data provide the concentration of nutrients (nitrate, ammonium and FeⅡ) in the atmosphere and their deposited flux in the East China Sea prior to the harmful algal bloom on May 3-8, 2006. They can be helpful for analyzing the source of nutrients causing the harmful algal blooms.

Knockdown of long non-coding RNA prostate cancer-associated transcript 1 inhibits the proliferation and metastasis of tongue squamous cell carcinoma cells by upregulating p21.

Long non-coding RNA (lncRNA) prostate cancer-associated transcript 1 (PCAT-1) is a long non-coding RNA involved in the development of various cancer types. Tongue squamous cell carcinoma (TSCC) is the most frequently diagnosed type of oral cancer worldwide. The present study aimed to explore the role of lncRNA PCAT-1 in TSCC, and to provide a preliminary assessment of the downstream pathways involved. The expression levels of lncRNA PCAT-1 in TSCC specimens were first assessed. Subsequently, lncRNA PCAT-1 was knocked down in TSCC cell lines and the resulting effect on the proliferation and apoptosis, as well as the metastatic and invasive potential of TSCC cells was investigated. To assess the downstream signaling resulting from lncRNA PCAT-1 inhibition, the expression of p21 was also detected. The results indicated that lncRNA PCAT-1 was upregulated in clinical TSCC compared with peri-tumor tissues. Inhibition of lncRNA PCAT-1 resulted in reduced proliferation and apoptosis of TSCC cells, in addition to the suppression of migration and invasion. Furthermore, the expression of p21 was induced following lncRNA PCAT-1 inhibition. Collectively, the present study demonstrated an oncogenic role for lncRNA PCAT-1 in TSCC; inhibition of lncRNA PCAT-1 reduced the growth, metastasis and invasion of TSCC, at least in part via the induction of p21 signaling.

Algae explosive growth mechanism enabling weather-like forecast of harmful algal blooms.

As a global problem in coastal environments, harmful algal blooms (HABs) have seriously affected the health of coastal ecosystems and regional economies. Here we report an aerosol-trigger mechanism for the occurrence of HABs based on long-term field data and laboratory experiments. The occurrence times of HABs and aerosol events had a significant correlation from 2005 to 2013 in the East China Sea, indicating that aerosol transport was probably an alternative trigger of HABs. HABs mostly occur in the transition time between winter and summer, during which northwest monsoon transport substantial aerosol (rich in phosphate, iron and other trace metals) to coastal waters, as revealed by chemical measurements, transmission electron microscope and electron microprober results. Such nutrients can stimulate algal growth in our incubation experiments, suggesting that such aerosol transport can be important nutrient sources for the East China Sea where phytoplankton growth is relatively phosphate limited. Air-borne nutrients are available for algal growth by rapid downward air flow, which additional results a clear weather condition, and thus adequate light intensity for algal growth. At last, the transition from northwest monsoon to warm southwest monsoon establishes favorable seawater temperature for algal blooms. Such weather-related aerosol-trigger mechanism suggests possibly forecast of HABs.