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Bioinformatics
; 37(20): 3673-3675, 2021 Oct 25.
Artículo
en Inglés
| MEDLINE
| ID: mdl-33964130
RESUMEN
MOTIVATION: Simulation-based inference can bypass the limitations of statistical methods based on analytical approximations, but software allowing simulation of structured population genetic data without the classical n-coalescent approximations (such as those following from assuming large population size) are scarce or slow. RESULTS: We present GSpace, a simulator for genomic data, based on a generation-by-generation coalescence algorithm taking into account small population size, recombination and isolation by distance. AVAILABILITY AND IMPLEMENTATION: Freely available at site web INRAe (http://www1.montpellier.inra.fr/CBGP/software/gspace/download.html).