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1.
ACS Omega ; 9(31): 33643-33651, 2024 Aug 06.
Artículo en Inglés | MEDLINE | ID: mdl-39130594

RESUMEN

Self-powered wearable electronic products have rapidly advanced in the fields of sensing and health monitoring, presenting greater challenges for triboelectric materials. The limited surface polarity and structural defects in wood fibers restrict their potential as substitutes for petroleum-based materials. This study used bagasse fiber as the raw material and explored various methods, including functionalizing cellulose nanofibrils (CNFs) with polydopamine (PDA), in situ embedding of silver particles, filtration, and freeze-drying. These methods aimed to enhance the triboelectric output, antibacterial properties, and filtration properties of lignocellulosic materials. The Ag/PDA/CNF-based triboelectric nanogenerator (TENG) demonstrated an open-circuit voltage of 211 V and a short-circuit current of 18.1 µA. An aerogel prepared by freeze-drying the Ag/PDA/CNF material, combined with a polyvinylidene fluoride nanofiber structure fabricated by electrospinning, constitutes the TENG unit. A self-powered respiratory detection mask was created using this combination, achieving a filtration efficiency of 94.23% for 0.3 µm particles and an antibacterial rate exceeding 99%. In addition, it effectively responded to respiratory frequency signals of slow breathing, normal breathing, and shortness of breath, with the output electrical signal correlating with the respiratory frequency. This study considerably contributes to advancing wood fiber-based triboelectric materials as alternatives to petroleum-derived materials in self-powered wearable electronic products for medical applications.

2.
Polymers (Basel) ; 16(10)2024 May 16.
Artículo en Inglés | MEDLINE | ID: mdl-38794606

RESUMEN

Self-powered electronic equipment has rapidly developed in the fields of sensing, motion monitoring, and energy collection, posing a greater challenge to triboelectric materials. Triboelectric materials need to enhance their electrical conductivity and mechanical strength to address the increasing demand for stability and to mitigate unpredictable physical damage. In this study, polyaniline-modified cellulose was prepared by means of in situ polymerization and compounded with polydimethylsiloxane, resulting in a triboelectric material with enhanced strength and conductivity. The material was fabricated into a tubular triboelectric nanogenerator (TENG) (G-TENG), and an electrocatalytic pretreatment of mixed office waste paper (MOW) pulp was performed using papermaking white water as the flowing liquid to improve the deinking performance. The electrical output performance of G-TENG is highest at a flow rate of 400 mL/min, producing a voltage of 22.76 V and a current of 1.024 µA. Moreover, the deinking effect of MOW was enhanced after the electrical pretreatment. This study explores the potential application of G-TENG as a self-powered sensor power supply and emphasizes its prospect as an energy collection device.

3.
APL Bioeng ; 8(2): 021504, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38638143

RESUMEN

As a primary malignant bone cancer, osteosarcoma (OS) poses a great threat to human health and is still a huge challenge for clinicians. At present, surgical resection is the main treatment strategy for OS. However, surgical intervention will result in a large bone defect, and some tumor cells remaining around the excised bone tissue often lead to the recurrence and metastasis of OS. Biomedical Mg-based materials have been widely employed as orthopedic implants in bone defect reconstruction, and, especially, they can eradicate the residual OS cells due to the antitumor activities of their degradation products. Nevertheless, the fast corrosion rate of Mg alloys has greatly limited their application scope in the biomedical field, and the improvement of the corrosion resistance will impair the antitumor effects, which mainly arise from their rapid corrosion. Hence, it is vital to balance the corrosion resistance and the antitumor activities of Mg alloys. The presented review systematically discussed the potential antitumor mechanisms of three corrosion products of Mg alloys. Moreover, several strategies to simultaneously enhance the anticorrosion properties and antitumor effects of Mg alloys were also proposed.

4.
Polymers (Basel) ; 14(17)2022 Aug 28.
Artículo en Inglés | MEDLINE | ID: mdl-36080611

RESUMEN

The hydroxyl groups on the cellulose macromolecular chain cause the cellulose surface to have strong reactivity. In this study, 1H, 1H, 2H, 2H-perfluorodecyltriethoxysilane (PDOTES) was used to modify cellulose to improve its triboelectric properties, and a triboelectric nanogenerator (TENG) was assembled. The introduction of fluorine groups reduced the surface potential of cellulose and turned it into a negative phase, which enhanced the ability to capture electrons. The electrical properties increased by 30% compared with unmodified cellulose. According to the principles of TENGs, a self-powered human-wearable device was designed using PDOTES-paper, which could detect movements of the human body, such as walking and running, and facilitated a practical method for the preparation of efficient wearable sensors.

5.
Aging (Albany NY) ; 13(9): 12631-12640, 2021 04 27.
Artículo en Inglés | MEDLINE | ID: mdl-33910166

RESUMEN

BACKGROUND: Obesity is an important part of polycystic ovary syndrome (PCOS) pathologies. The present study utilized the bioinformatics method to identify the molecular mechanism of obesity status in PCOS. METHODS: Six transcriptome profiles of adipose tissue were obtained from online databases. The background correction and normalization were performed, and the DEGs were detected with the settings p < 0.05. The GO, KEGG pathway enrichment, and PPI network analysis were performed with the detected DEGs. RESULTS: A total of 37 DGEs were found between obesity PCOS and healthy controls, and 8 of them were tested significant in the third database. The expression patterns of the 8 detected DGEs were then measured in another two datasets based on lean/obesity PCOS patients and healthy controls. The gene CHRDL1 was found to be in linear regression with the BMI index in PCOS patients (p = 0.0358), but such a difference was not found in healthy controls (p = 0.2487). The expression of CHRDL1 was significantly higher in obesity PCOS cases than the BMI matched healthy controls (p = 0.0415). Further enrichment research demonstrated the CHRDL1 might function as an inhibitor of the BMP4 or IGF1 signalling. CONCLUSION: In summary, the present study identified CHRDL1 as a candidate gene responsible for the obesity of PCOS patients.


Asunto(s)
Obesidad/genética , Obesidad/metabolismo , Síndrome del Ovario Poliquístico/genética , Síndrome del Ovario Poliquístico/metabolismo , Índice de Masa Corporal , Proteína Morfogenética Ósea 4/genética , Proteínas del Ojo/genética , Proteínas del Ojo/metabolismo , Femenino , Humanos , Factor I del Crecimiento Similar a la Insulina/genética , Factor I del Crecimiento Similar a la Insulina/metabolismo , Proteínas del Tejido Nervioso/genética , Proteínas del Tejido Nervioso/metabolismo , Transducción de Señal/genética , Transducción de Señal/fisiología
6.
Phytother Res ; 34(6): 1237-1247, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-31919936

RESUMEN

Water-soluble dietary fibers have been shown to improve lipid profile and glucose metabolism in diabetes. The aim of this study was to review the effects of psyllium consumption on weight, body mass index, lipid profiles, and glucose metabolism in diabetic patients in randomized controlled trials. A comprehensive systematic search was performed in PubMed/MEDLINE, Web of Sciences, Cochrane, and Scopus by two independent researchers up to August 2019 without any time and language restrictions. The DerSimonian and Laird random-effects model method performed to calculate the pooled results. Inclusion criteria were randomized controlled trial design, adult subjects, and studies reporting the mean differences with the 95% confidence interval for outcome. Eight studies containing nine arms with 395 participants were identified and included in final analysis. Combined results found a significant reduction in triglycerides, low-density lipoprotein, fasting blood sugar, and hemoglobin A1c following psyllium consumption (weighted mean differences [WMD]: -19.18 mg/dl, 95% CI [-31.76, -6.60], I2 = 98%), (WMD: -8.96 mg/dl, 95% CI [-13.39, -4.52], I2 = 97%), (WMD: -31.71 ml/dl, 95% CI [-50.04, -13.38], I2 = 97%), and (WMD: -0.91%, 95% CI [-1.31, -0.51], I2 = 99%), respectively. There was no significant change in high-density lipoprotein, body mass index, cholesterol, and weight. In conclusion, the results demonstrated a significant reduction in triglycerides, low-density lipoprotein, fasting blood sugar, and hemoglobin A1c by psyllium intervention among diabetic patients.


Asunto(s)
Glucemia/efectos de los fármacos , Índice de Masa Corporal , Peso Corporal/efectos de los fármacos , Diabetes Mellitus/tratamiento farmacológico , Lípidos/sangre , Psyllium/uso terapéutico , Adulto , Glucemia/metabolismo , Humanos , Masculino , Ensayos Clínicos Controlados Aleatorios como Asunto
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