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1.
Wien Med Wochenschr ; 165(15-16): 304-9, 2015 Aug.
Artículo en Alemán | MEDLINE | ID: mdl-26249006

RESUMEN

The aim of the present study was to determine whether pupillometry was able to identify and differentiate psychopathic personality traits in criminally responsible mentally disordered offenders (§ 21/2 StGB). Psychopathic disorder has not only behavioral, but also psychophysiological correlates, which may be evaluated by pupillometry. This might make it possible to diagnose psychopathy by means of a non-invasive method and in a further step to adapt therapeutic measures accordingly. Psychopathic behavior and personality traits were identified by means of the Hare Psychopathy Checklist-Revised (PCL-R) and offenders were divided into 4 groups with PCL-R scores of 0-10, 11-20, 21-30 and 31-40, respectively. Pupillometry makes it possible to objectively measure amplitudes of pupillary oscillations, which may serve as an indicator of central nervous activation/deactivation. The study at hand showed that the higher the PCL-R values, the smaller the amplitudes. Thus, it can be concluded that central nervous activation decreases with higher PCL-R values and psychopathy is associated with central nervous deactivation.


Asunto(s)
Trastorno de Personalidad Antisocial/diagnóstico , Trastorno de Personalidad Antisocial/fisiopatología , Nivel de Alerta/fisiología , Prisioneros/psicología , Trastornos Psicóticos/diagnóstico , Trastornos Psicóticos/fisiopatología , Reflejo Pupilar/fisiología , Trastorno de Personalidad Antisocial/psicología , Sistema Nervioso Central/fisiopatología , Lista de Verificación , Comorbilidad , Humanos , Masculino , Variaciones Dependientes del Observador , Psicometría/estadística & datos numéricos , Trastornos Psicóticos/psicología , Reproducibilidad de los Resultados
2.
Wien Med Wochenschr ; 162(7-8): 176-81, 2012 Apr.
Artículo en Alemán | MEDLINE | ID: mdl-22451085

RESUMEN

BACKGROUND: Pupillometry is a non-invasive investigation based on the concept that pupillary reagibility depends on a number of specific sensory, mental and emotional variables. By means of the receptor test based on the topical application of the cholinergic antagonist tropicamide cognitive deficits can be evaluated. The present study focuses on the question whether the receptor test is able to differentiate criminally responsible mentally disordered offenders (§ 21/2 StGB) with different durations of confinement concerning the presence of a functional psychosyndrome, as defined by Grünberger. METHODS: Four groups of offenders with different durations of confinement (group A: confinement 0-2 years, n = 26, X = 33; group B: 2-5 years, n = 29, X = 34; group C: 5-10 years, n = 6, X = 36; group D: >10 years, n = 10, X = 43) were investigated by means of a computer-assisted TV pupillometer. After a baseline measurement 0.01% tropicamide was instilled into the eye. The second measurement was conducted 20 min after the first, the 3rd and 4th measurements in intervals of 20 min. RESULTS: The groups with a longer duration of confinement showed a reduced activation and vigilance and increased fatigability as compared with the groups of shorter confinement. In the receptor test the group that had been imprisoned for 0-2 years showed more cognitive deficits than those imprisoned for ≥5 years. CONCLUSIONS: Evaluation of activation, fatigability and vigilance indicates that the duration of confinement plays a role in the development of a functional psychosyndrome. The results of the receptor test, in which the group with a longer duration of confinement showed less pronounced cognitive deficits and no significant changes of the tropicamide effect over time, suggest that in this group a dose change might be required to make the cognitive deficits evident.


Asunto(s)
Trastornos del Conocimiento/diagnóstico , Internamiento Obligatorio del Enfermo Mental , Diagnóstico por Computador , Electrodiagnóstico , Tiempo de Internación , Trastornos Neurocognitivos/diagnóstico , Adulto , Nivel de Alerta , Fatiga/diagnóstico , Humanos , Masculino , Persona de Mediana Edad , Antagonistas Muscarínicos , Pruebas Neuropsicológicas , Reflejo Pupilar/efectos de los fármacos , Síndrome , Tropicamida
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