Novel Passive Two-Stage Magnetic Targeting Devices for Distal Locking of Interlocking Nails.

Interlocking nailing is a common surgical operation to stabilize fractures in long bones. One of the difficult parts of the surgery is how to locate the position and direction of a screw hole on the interlocking nail, which is invisible to the naked eye after insertion of the nail into the medullary canal. Here, we propose a novel two-stage targeting process using two passive magnetic devices to locate the position and direction of the screw hole without radiation for the locking screw procedure. This involves a ring-shape positioning magnet inside the nail to generate a magnetic field for targeting. From the accuracy test results of these two-stage targeting devices, the search region can be identified in less than 20 seconds by the 1st-stage targeting device, while the total targeting time to locate the drilling position and direction takes less than 4 minutes, with 100% successful rate in 50 attempts. The drilling test further combines the two-stage targeting process and drilling process on the swine tibia, and it is shown that a 100% successful rate is achieved in all 10 attempts, where the total time needed is less than 5 minutes.

Wireless EWOD/DEP chips powered and controlled through LC circuits and frequency modulation.

This paper presents novel wireless EWOD/DEP chips that are wirelessly powered and controlled through LC circuits with one-to-many transmitter-receiver coupling. Each receiving LC circuit connected to the EWOD/DEP electrode is designed to have a different resonant frequency. When the input frequency is close to one of the resonant frequencies of receiving LC circuits, the induced voltage on the corresponding EWOD/DEP electrode will increase due to the resonance. Therefore, electrodes can be selectively and sequentially activated to provide sufficient EWOD or DEP force to manipulate the droplet or liquid by modulating the input frequency. Unlike previously reported wireless EWOD or DEP devices powered through one-to-one transmitter-receiver coupling, the transmitting inductor in the one-to-many transmitter-receiver coupling design proposed here is much larger than the total sizes of receiving inductors. Therefore, receiving inductors can be easily covered and coupled by the transmitting inductor. Here, droplet transport, splitting, and merging are successfully demonstrated using 5 receiving LC circuits at different input frequencies (1210-1920 Hz). Liquid pumping with multiple electrodes by wireless DEP is also demonstrated using 5 receiving LC circuits at higher input frequencies (51.2-76.1 kHz). Furthermore, liquid pumping with a continuous meandered electrode by wireless DEP is demonstrated through the resonant frequency shifting effect. It shows that the liquid pumping distance on a continuous electrode also can be tuned by proper frequency modulation.