[Effects of water and nitrogen coupling under furrow irrigation on tree growth, absorption and utilization of water and nitrogen of Populus tomentosa]. / 沟灌水氮耦合对毛白杨林木生长及水氮吸收利用的影响.

We explored the coupling effects of water and nitrogen in furrow irrigation on the growth and absorption and utilization of water and nitrogen in young poplar trees (triploid Populus tomentosa), under three irrigation levels (W20, W33, W45; when the soil water potential of 40 cm under the ditch reaches -20, -33 and -45 kPa respectively, irrigate), four N application levels (N120, N190, N260 and N0; the fertilization amount was 120, 190, 260 and 0 kg·hm-2·a-1), and natural conditions (CK). Based on the growth status of trees, the optimal combination of irrigation level and nitrogen application rate under furrow irrigation conditions was determined. The results showed that W20N120 (high water and low fertilizer; soil water potential threshold for initiating irrigation was -20 kPa and N application rate was 120 kg·hm-2·a-1) had the strongest effect on the stand productivity, with a value of 33.37 m3·hm-2·a-1. The significant coupling effect of water and N was detected only for tree height and total individual biomass. The increase of both irrigation amount and N application rate could increase the amount of N uptake, being mainly affected by the latter. The total amount of N uptake was the highest in the W20N260 treatment and reached 112.17 kg·hm-2·a-1, being 74.0% higher than that in CK. Among all the treatments, N uptake efficiency and N fertilizer partial productivity of W20N120 were the highest and significantly higher than those of the other treatments. The N uptake efficiency of the whole plant, aboveground part, and belowground part reached 36.8%, 28.5% and 6.4% in the W20N120 treatment, and its total N partial productivity reached 221.4 kg·kg-1. The effect of irrigation amount under different water-nitrogen coupling treatments on the irrigation water use efficiency was significant. Among them, irrigation water use efficiency in W45N260 was the highest and reached 13.66 g·kg-1. W20N120 had the highest water uptake amount and efficiency, which were 13268.28 t·hm-2 and 129.4%, respectively. To achieve great benefits, adequate irrigation (-20 kPa) and relatively low N application rate (120 kg·hm-2·a-1) should be selected during the young growth of the triploid P. tomentosa.

Efficacy and survival-associated factors with gefitinib combined with cisplatin and gemcitabine for advanced non- small cell lung cancer.

OBJECTIVE: To analyze the efficacy and survival associated factors of gefitinib combined with cisplatin and gemcitabine for advanced non-small cell lung cancer. MATERIALS AND METHODS: A total of 57 patients with advanced non-small cell lung cancer (NSCLC), who received platinum-based chemotherapy regimens for more than 1 cycle, were treated with gefitinib combined with cisplatin and gemcitabine until disease progression. Efficacy, survival time and adverse reactions were observed. The Kaplan-Meier method was adopted for analysis of survival and Cox regression for associated influencing factors. RESULTS: The patients were followed up until October 31, 2013, and the median follow-up time was 19 months. Of 57 patients, there were 4 (7.0%) with complete remission (CR), 8 (14.0%) with partial remission, 31 (54.4%) with stable disease, and 14 (24.6%) with disease progression. The remission rate was 21.1% and the disease control rate was 75.4%. The median progression-free survival (PFS) time and the median overall survival time were 10 months and 15.2 months. The one-year, two-year and three- year survival rates were 47.4%, 23.3% and 10.0%. Gender and pathological types were the independent risk factors influencing PFS time (P=0.028, P=0.009). Tumor pathological type and early efficacy were independent factors for the prognosis (P=0.018, P=0.000). Adverse reactions were mostly rashes of I~II degree and diarrhea and slightly increasing level of aminopherase. The skin adverse event incidence of III degree or above was 1.8% (1/57) and brain metastasis was foudn in 31.6% (18/57). CONCLUSIONS: Gefitinib combined with cisplatin andgemcitabine, is effective for patients with IIIb~IV NSCLC who received multiple cycles of chemotherapy.

[Progress of taxonomic study on Fritillaria (Liliaceae) medicinal plant].

In this review, we described the taxonomic study of the Fritillaria medicinal plant in the recent years. The taxonomic study of the Fritillaria medicinal plant was carried out from three main aspects: the traditional morphological character, the characteristic constituents of the plant and genotyping and species identification of Fritillaria by DNA chips. By comparison, we concluded that the DNA chip technology can provide a rapid, high throughput for genotyping and quality assurance of the plant species verification. It is the most prosperous method of species identification of the plant.

[Identification of Chinese medicine material of Fritillaria by themogravimetric/diffrential thermal analysis].

OBJECTIVE: To provide a quick and simple method to identify different Chinese medicine material of Fritillaria. METHOD: The thermograms and differential thermograms of nine Fritillaria powders were obtained by thermal analyzer. RESULT: By analyzing the thermograms of nine Fritillaria powders, we concluded that the thermal stability of nine Fritillaria powders was much different each other due to the different geography origin. The thermal stability of F. hupehensis was highest among nine Fritillaria, while F. ussurensis was the lowest. The different Fritillaria showed their own DTA spectra respectively. CONCLUSION: According to the differences in the thermal properties of nine Fritillaria powders, the origins of Fritillaria could be easily identfied.