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1.
Front Physiol ; 15: 1340441, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38846420

RESUMEN

Introduction: Fetal heart rate variability (fHRV) is a tool used to investigate the functioning of the fetal autonomic nervous system. Despite the significance of preeclampsia, fHRV during the latent phase of labor has not been extensively studied. This study aimed to evaluate fetal cardiac autonomic activity by using linear and nonlinear indices of fHRV analysis in women diagnosed with preeclampsia without hypertensive treatment during gestation, compared to normotensive women during the latent phase of labor. Methods: A cross-sectional and exploratory study was conducted among pregnant women in the latent phase of labor, forming three study groups: normotensive or control (C, 38.8 ± 1.3 weeks of pregnancy, n = 22), preeclampsia with moderate features (P, 37.6 ± 1.4 weeks of pregnancy n = 10), and preeclampsia with severe features (SP, 36.9 ± 1.2 weeks of pregnancy, n = 12). None of the participants received anti-hypertensive treatment during their pregnancy. Linear and nonlinear features of beat-to-beat fHRV, including temporal, frequency, symbolic dynamics, and entropy measures, were analyzed to compare normotensive and preeclamptic groups. Results: Significantly lower values of multiscale entropy (MSE) and short-term complexity index (Ci) were observed in the preeclamptic groups compared to the C group (p < 0.05). Additionally, higher values of SDNN (standard deviation of R-R intervals) and higher values of low-frequency power (LF) were found in the P group compared to the C group. Conclusion: Our findings indicate that changes in the complexity of fetal heart rate fluctuations may indicate possible disruptions in the autonomic nervous system of fetuses in groups affected by undiagnosed preeclampsia during pregnancy. Reduced complexity and shifts in fetal autonomic cardiac activity could be associated with preeclampsia's pathophysiological mechanisms during the latent phase of labor.

2.
Sci Prog ; 104(2): 368504211016954, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33979251

RESUMEN

As a parameter important ballistic, the research about polygonal and grooved barrels' behavior has not been widely carried out. The pressures, velocities, stresses, deformations, and strains generated by the firing of 9 mm × 19 mm ammunition in weapons with polygonal barrels are analyzed numerically and experimentally, compared with those generated in pistols with grooved barrels. The Finite Element Method with equal boundary and loading conditions was used in both types of guns, specifying the actual materials of the projectile and the barrels. Subsequently, experimental tests were carried out on various weapons with 9 mm ammunitions of 115, 122, and 124 gr. The results show that the 9 mm bullet fired in a polygonal barrel undergoes a maximum deformation towards its exterior of 0.178 mm and interior of 0.158 mm, with stress up to 295.85 MPa. Compared with 0.025 mm maximum external deformation and 0.112 mm internal deformation of 9 mm projectiles fired in a grooved barrel, with stress up to 269.79 MPa. The deformation in the polygonal barrel is in a greater area, but the rifling impression left is less deep, making its identification more difficult. Although there are differences in the stresses and strains obtained, similar velocity and pressure parameters are achieved in the two types of barrels. This has application in the development and standardization of new kinds of barrels and weapons.

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