Asunto(s)
Hígado/metabolismo , Radiofármacos/farmacocinética , Bazo/metabolismo , Medronato de Tecnecio Tc 99m/farmacocinética , Macroglobulinemia de Waldenström/diagnóstico por imagen , Femenino , Humanos , Persona de Mediana Edad , Paraproteínas/análisis , Tomografía de Emisión de Positrones , Tomografía Computarizada por Rayos X , Macroglobulinemia de Waldenström/metabolismo , Imagen de Cuerpo EnteroAsunto(s)
Divertículo Ileal/diagnóstico por imagen , Pertecnetato de Sodio Tc 99m , Niño , Humanos , Masculino , Cintigrafía , RadiofármacosAsunto(s)
Enfermedades de las Arterias Carótidas/diagnóstico por imagen , Enfermedades de las Arterias Carótidas/metabolismo , Enfermedad de Moyamoya/diagnóstico por imagen , Enfermedad de Moyamoya/metabolismo , Medronato de Tecnecio Tc 99m/metabolismo , Adolescente , Enfermedades de las Arterias Carótidas/complicaciones , Femenino , Humanos , Enfermedad de Moyamoya/complicaciones , CintigrafíaRESUMEN
A 64-year-old woman presented with a painless breast mass. Tc-99m methoxyisobutylisonitrile scintigraphy of both breasts showed a local area of abnormal uptake in the left breast in 5 min and 2 h. A skeletal scan showed very intense concentration of activity in the primary breast tumor in the left breast. A left mastectomy and an axillary dissection were performed. The predominant histologic type of the mass was an osteosarcoma, and the diagnosis of a primary osteogenic sarcoma of the breast was made. Primary osteogenic sarcoma of the breast is rare and represents less than 1% of all primary breast malignancies.
Asunto(s)
Neoplasias de la Mama/diagnóstico por imagen , Osteosarcoma/diagnóstico por imagen , Medronato de Tecnecio Tc 99m , Tecnecio Tc 99m Sestamibi , Femenino , Humanos , Persona de Mediana Edad , Cintigrafía , Radiofármacos , Enfermedades Raras/diagnóstico por imagenRESUMEN
OBJECTIVE: To evaluate the performance of 18F-FDG three-head tomography with coincidence imaging and serum tumor marker assays in identifying lung lesions in 104 patients with abnormal findings on chest X-ray or computer tomography. METHODS: A prospective evaluation of 18F-FDG coincidence imaging and the measurement of 3 serum markers for lung cancer ( carcinoembryonic antigen, CYFRA21-1 and neuron specific enolase) were performed within one week in 104 inpatients with suspected lung malignancy. All images were analyzed visually. It was considered positive for malignancy if the 18F-FDG uptake was increased relative to that in the adjacent lung tissue, and was focal. The serum tumor marker test was considered positive for malignancy if the serum level of at least one marker was elevated. RESULTS: 66 patients were proven to have lung cancer by pathology, and 38 patients had benign lung diseases. The sensitivity, specificity, accuracy of 18F-FDG coincidence imaging and serum tumor markers in assessing lung cancers were 80. 0% , 77. 2% , 77. 9% and 56. 0% , 60. 9%, 64. 4% , respectively. 18F-FDG coincidence images in assessing lung lesions showed significantly higher sensitivity, specificity and accuracy than serum tumor markers. Four patients with lung cancer had negative findings on 18F-FDG coincidence images but showed positive serum markers. CONCLUSION: 18F-FDG coincidence imaging is a powerful tool for evaluating patients with lung lesions suggestive of malignancy. Although the determination of serum marker levels is less accurate than 18F-FDG coincidence imaging, the combination of a positive 18F-FDG coincidence result and positive tumor markers may be helpful in improving the diagnosis of lung cancers.
Asunto(s)
Biomarcadores de Tumor/sangre , Carcinoma de Células Escamosas/diagnóstico , Fluorodesoxiglucosa F18 , Neoplasias Pulmonares/diagnóstico , Adulto , Anciano , Anciano de 80 o más Años , Antígenos de Neoplasias/sangre , Antígeno Carcinoembrionario/sangre , Carcinoma de Células Pequeñas/sangre , Carcinoma de Células Pequeñas/diagnóstico , Carcinoma de Células Pequeñas/diagnóstico por imagen , Carcinoma de Células Escamosas/sangre , Carcinoma de Células Escamosas/diagnóstico por imagen , Femenino , Humanos , Queratina-19 , Queratinas/sangre , Neoplasias Pulmonares/sangre , Neoplasias Pulmonares/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Fosfopiruvato Hidratasa/sangre , Granuloma de Células Plasmáticas del Pulmón/sangre , Granuloma de Células Plasmáticas del Pulmón/diagnóstico , Granuloma de Células Plasmáticas del Pulmón/diagnóstico por imagen , Tomografía de Emisión de Positrones , Estudios Prospectivos , Radiofármacos , Sensibilidad y Especificidad , Tuberculosis Pulmonar/sangre , Tuberculosis Pulmonar/diagnóstico , Tuberculosis Pulmonar/diagnóstico por imagenRESUMEN
OBJECTIVE: To evaluate the accuracy of [18F] fluorodeoxyglucose (FDG) triple-head coincidence imaging in the setting of suspected lung cancer. METHODS: 109 patients with suspected lung cancer were enrolled in the present study. According to the diameter of the lesion (> 1.5 cm, 1.5 cm, the sensitivity, specificity and accuracy were 98% (81/83)), 63% (10/16) and 92% (91/99), respectively. While for the group of lesion diameter